EXAM 1 - Week 1 to 3 Flashcards
What occurs when RPE starts to disengrate?
Photoreceptors cannot recycle, thus dying off
What is photopic vision?
Where cones predominatly function
What gives the retina its duplex property?
Rods and Cones
What is mesopic?
Combination of cones and rods function
What is scotopic?
Where rods predominantly function
Where is the opsin found in rods and cones?
In the outer segment
What photoreceptor sheds its discs
Rods
What is the maximum absorption (not sensitivity) of rod wavelength?
Around 500nm - Green color
Note: Rods are most sensitive to Violet color
What is sensitivity of cone wavelenght?
S-420 - Blue
M-530 - Blue - Green
L - 560 -Yellow - Green
What is the Rod sensitivity in nm?
498
What is the physiological dark adapt time?
35 minutes
How many photons can a rod be stimulated for vision to occur?
100’s of rods
How many photons are needed to stimulate a rod?
1 photon
In order by wavelength, put the photoreceptor in order.
Blue, Rod, Green and Red
True or False, you can detect one photon of light.
False. You personally cannot but your rod can
Is there an area where there are no photoreceptors?
Yes, the optic disc
What do we have more of rods or cones in the eye?
Rods
Where is the peak of cones?
Outside the fovea, 20 to 30 degrees
What is predominantly found in the fovea?
L and M cones
What is more dominant between L and M cones?
Varies. From 1 to 1 or 16 to 1 (M to L)
What is Dr. Cameron’s research with Zebra fish being conducted?
AMD
What is the lowest threshold for a Cone response, in regards to Dark Adaptation?
10 minutes
When do rods start functioning in regards to Dark Adaptation and when is the threshold met?
Don’t start till 10 minutes and 20 minutes after there is a threshold
What is the photochromatic interval?
Difference between rod plateau and cone plateau interval
At 35 minutes, what is the sensitivity of the human eye in dark adaption?
100,000 times more
What are the 5 areas where Dark Adaption can be effected?
Light Intensity - Brighter the room, the longer it takes to recover
Light Duration
Wavelength - What wavelength are rods sensitve to (Violet)
Location
Rhodopsin regeneration - slower regeneration and takes a while
What are the 4 sub-titles for the parting the curve graph?
Note: background must be red and stimulus is green
1 - Dark Light
2 - Square Root Law
3 - Weber’s law - slope will be the same for scoptic and photopic
4 - Saturation
What is a quanta in the nervous system?
1 packet of a neurotransmitter
You pt. a rod monochromat, has asked for advice regarding tinted lenses. You should advise a darkly tinted lens of which color?
Red lenses
What color as a background will activate both rods and cones for light adaptation?
Green will be the background and Yellow be the test spot
Where does neural nose occur for rods?
Dark light
Where is the threshold start to pass the neural noise area?
square root law
where is traditional vision occurring?
Weber’s law - Most of this occurs here
Where is saturation occurring?
Saturation
How many ganglion cells will 10 rods connect to?
1 ganglion cell
How many cones will connect to a ganglion cell?
5 cones
What is Ricco’s law?
Looking at spatial summation, its the AREA you look at.
What happens when a threshold has been achieved?
An action potential occurs
What is the type of summation that is rated over time?
Temporal Summation
Note: If you see a flash within 100ms, you will only see one flash in the Scotopic
Note: If you see any flash over 10m/s, you will see more than one flash
What is the stiles crawford effect?
Light has to strike a cone perpendicularly, while for rods it doesn’t matter.
What is the sclera largely consist of?
Collagen
How much refraction power does the cornea provide?
2/3 of refractive power entering the eye (40D)
What happens to the lens when you would like to increase the power of the lens?
Decrease the curvature of anterior lens surface
What part of photoreceptors does adaption for transmitting the neural signal?
Innermost PR cells
What type of photopigment is located in Rods and Cones?
Rods - Rhodopsin
Cones - Opsin
Where are rods located the most?
Outside of the fovea.
How many discs is a rod made of?
600 to 1000
Note: Disc membrane is seperate from the plasma membrane of the cell except at the base
When do rods shed?
During the day, specifically the evening
What is the name of the specialized terminal of a rod?
Spherule
Where are cones predominantly located?
20 to 30 degrees outside the fovea.
True or False. The plasma membrane of the photoreceptor is Continous with the disc membrane of the Cone.
True
Where are the cell bodies of bipolar cells, HC, AC, Interplexiform cells and Mueller cells located in the retina?
Inner Nuclear Layer
What is the % of Small midget GC’s in the eye?
80%
What is the % of Large Parasol GC’s in the eye?
10%
How many degrees away is the optic disc away from the fixation point?
15 degrees
What is the primary target for the optic tract?
LGN
Which layers receive input from the ipsilateral eye?
2, 3, 5