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BECOM 4 > Exam #1 (Pathology) > Flashcards

Exam #1 (Pathology) Flashcards

1
Q

CD31

A

hepatic angiosarcoma

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2
Q

vinyl chloride
arsenic
thorium dioxide

A

hepatic angiosarcoma

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3
Q

hepatic angiosarcoma transplant?

A

no high rate of recurrence

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4
Q

most common benign liver tumor

A

cavernous hemangioma

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5
Q

rupture during biopsy

A

cavernous hemangioma
hepatic angiosarcoma
hepatic adenoma

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6
Q

dye filling tumor from outside -> in

A

cavernous hemangioma

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7
Q

vascular spaces line w single layer of flat endothelium filled w blood

A

cavernous hemangioma

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8
Q

contraceptive use

A

hepatic adenoma

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9
Q

hepatic adenoma risk

A

risk of rupture during pregnancy (uncapsulated)

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10
Q

hepatocellular labs

A

hypoglycemia
inc EPO
hypercalcemia
inc AFP

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11
Q

diffuse atrophic gastritis cause

A

autoimmune gastritis

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12
Q

autoimmune gastritis associated w

A

inc risk of gastric adenoocarcinoma

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13
Q

menetrier disease

A

inc TGFa and mucous secretion leading to hypoproteinemia

-hyperplasia of foveolar mucous cells

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14
Q

elongated/corkscrew appearance and cystic dilation

A

menetrier disease

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15
Q

gastric hyperplastic polyps cause

A

h. pylori

chronic gastritis

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16
Q

gastric fundic gland polyps cause

A

FAP

PPI use

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17
Q

inc gastric adenoma polyps means

A

inc risk for adenocarcinoma

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18
Q

intestinal gastric adenocarcinoma main cause

A

nitrosamine

develop from previous lesions

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19
Q

Diffuse gastric adenocarcinoma main cause and histo

A

BRCA2, E-cadherin, CDH1 mutation

signet rings on histo

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20
Q

Diffuse gastric adenocarcinoma is described as

A

linitis plastica - leather bottle appearance from wall thickening

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21
Q

gastric lymphoma mutation

A

t(11;18)(q21;q21)

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22
Q

gastric lymphoma marker

A

CD43+

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23
Q

GIST definition

A

mesenchymal tumor of the abdomen that arises from interstitial cells of cajal

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24
Q

Carney Triad

A

GIST
paraganglioma
pulmonary chondroma

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25
Q

GIST mutation

A

receptor tyrosine kinase KIT

PDGFRa

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26
Q

GIST prognosis

A

location, small intestine more aggressive

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27
Q

hyperplastic colonic polyps vs. adenomatous sessile serrated colonic polyps

A

hyperplastic colonic polyp: serrated surface restricted to upper 1/3
sessile serrated colonic polyps: serrated surface spands full length of gland

28
Q

Juvenile polyp mutation

A

SMAD

29
Q

high risk colonic polyps

A

villous

tubulovillous

30
Q

Peutz-Jeghers syndrome symp

A

multiple GI harmatomatous polyps + mucocutaneous hyperpigmentation

31
Q

Peutz-Jeghers mutation

A

STK11

32
Q

DNA mismatch repair most common polyps

A

sessile serrated

33
Q

hypertrophic pyloric stenosis

A

hyperplasia and hypretrophy

34
Q

Hirschsprung disease mutation

A

RET

35
Q

Gastroschisis vs omphalocele

A

inc AFP in gast

36
Q

scleroderma

A

preserved peristalsis in upper 1/3 of esophagus

37
Q

Ogilive’s syndrome

A

colonic pseudo-obstruction due to drugs or neurological problems
>9 cm emergency

38
Q

what fatty acids can go straight to blood

A

medium chain FA

39
Q

Carb malabsorption test

A

H+ breath test

stool pH <6

40
Q

go to test for pancreatic insuff

A

fecal elastase

41
Q

Cystic fibrosis will lead to

A

dec fat and protein breakdown

42
Q

bacterial overgrowth

A

> 10^5

43
Q

Peripheral IBD arthritis
Type 1
Type 2

A

Type 1: w flare ups, large joints, self limiting

Type 2: chronic, small joints

44
Q

PSC endoscopy

A

every year

45
Q

best for IBD diagnosis

A

CTE + colonoscopy

46
Q

celiac antibody

A

antiendomysial

47
Q

follow up EGD if poly is

A

> 2 cm

48
Q

MELD >15 means

A

good for transplant

49
Q

drug that induces steatosis

A

amiodarone
tamoxifen
Methotrexate

50
Q

INC ALT w

A

pancreatitis caused by obstruction >150

51
Q

Macro-amylasemia

A

poor renal excretion of amylase

inc creatinine

52
Q

celiac vs tropical

A

celiac: duodenal
tropical: all

53
Q

groove pancreatitis is associated w

A

duodenal atresia

54
Q

ABCB4 mutation

A

defective 7a hydroxylase

55
Q

Mirizzi syndrome seen, should suspect…

A

gallbladder cancer

56
Q

primary biliary cholangitis treatment

A

ursodeoxycholic acid

57
Q

GB polyp >… remove

A

10 mm

58
Q

Adenomatous GB polyps mean

A

cancerous

59
Q

autoimmune pancreatitis mutations

A

PRSS1

SPINK1

60
Q

pancreatic cancer marker

A

CA19-9

61
Q

Pancreatic cyst

Pseudocyst

A

CEA <200

amylase <200

62
Q

Pancreatic cyst

Mucinous

A

CEA >200
normal amylase
**malignant

63
Q

Pancreatic cyst

Serous

A

honey comb
central scar
cuboidal epithelium that is PAS+
amylase and CEA low

64
Q

Pancreatic cyst

Intraductal Papillary Mucinous Neoplasia

A

CEA >200

Amylase >200

65
Q

Hartnup disease

A

dec tyrosine absorption

BECOM 4 (4 decks)

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