Exam 1 - Part 3 Flashcards
what are the components of soft tissues
collagen, water, ground substance and elastin
is immature or mature collagen more stable?
Mature
what is the half life of collagen
weeks to months
what is collagen synthesized from
fibroblasts
Collagen can stretch to ____ of its original length without breaking
110%
elastin can stretch to ____ of its original length without breaking
150%
what happens to elastin as we age?
loses resiliency, fragments and frays, can calcify, increase # of cross links
an amorphous gel like substance that surrounds cells
ground substance
what is another name for ground substance?
“Cement Substance”
what are the contents of ground substance
GAG’s, plasma proteins, small proteins and water
what makes up _____% of total connective tissue content
60-70%
a __________ is a protein or peptide to which GAG’s are covalently attached
proteoglycan
what are the 4 major GAG’s
hyaluronic acid, chrondritin sulfate, (6 and 4) and dermatan sulfate
process by which water moves to areas of high solute concentration
osmosis
hyaluronic acid + Water = a powerful _______
lubricant
what maintains a critical distance between collagen fibers?
Water+Hyaluronic Acid Lubricant
- allows free gliding and prevents excessive cross linking
local shape change under the effect of applied forces is called
Deformation
when a structure is stretched longitudinally
tension
when a load produces a force that pushes the material together, creating a deforming stress
compression
combination of tensile and compressive loads
bending
when a load is applied parallel to the surface of the structure
shear
parallel forces in opposite directions about the long axis that cause twisting/rotation
torsion
which component of the body tends to bear tensile loads
annular fibers
when a strong contraction of the triceps surae muscle causes an avulsion at the calcaneos which type of force caused the fracture
tensile force
compressive forces are trasmitted to the _____ and ____ in the spine
Vertebral body and IVD
the _________ dissipates the compressive force in the spine by redirecting it outward radially
Nucleus Pulposus
Mechanical Failure first occurs in the ________ causing __________
Cartilaginous End Plate causing nuclear herniation (Schmorl’s Node)
additional failure to withstand compressive forces = ______
compression fracture
what type of force causes a Schmorls Node
Compressive
what type of force causes an anterior collapse of the vertebral body or end plate
Compression (in flexion)
compressive loads in extension are transmitted through the ______ leading to ___________
facets, capsular injuries
compressive loads applied with torque around the long axis (rotation) can produce ____________
circumferential tears in the annular fibers of the IVD
Compression + Rotation = ___________
annular fiber tear
Which type of force is a combination of compression and tension
bending