Exam 1 Part 2 Flashcards

1
Q

What is the term for abnormal leakage of fluid from the plasma to the interstitial spaces across the capillaries?

A

extracellular edema

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2
Q

T/F: Increased capillary filtration results in the increase in the permeability and surface area of the capillary.

A

True

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3
Q

With extracellular edema, fibrous tissue in the parenchymal cells results in these cells not being able to produce enough plasma proteins which results in what condition?

A

cirrhosis of the liver

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4
Q

T/F: loss of proteins in the urine due to kidney disease can result in nephrotic syndrome.

A

True

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5
Q

T/F: Renal diseases can cause damage to the glomeruli resulting in membranes blocking passage of proteins into the urine.

A

False; results in leaky membranes allowing passage of proteins into the urine.

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6
Q

T/F: With extracellular edema, increased capillary pressure can result in reduced kidney retention of salt and water.

A

False; can result in excessive kidney retention of salt and water

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7
Q

T/F: Extracellular edema can involve decreased plasma proteins, increased capillary permeability, and decreased lymph return.

A

true

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8
Q

T/F: Interstitial fluid hydrostatic pressure in loose subcutaneous tissues of the body is less than atmospheric pressure and creates a “suction” that holds the tissue together.

A

True

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9
Q

If interstitial fluid hydrostatic pressure in looses subcutaneous tissues is in the negative range, is that a small or a large interstitial hydrostatic pressure?

A

large

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10
Q

T/F: Edema helps to protect the body by decreasing lymph flow.

A

False; actually increases lymph flow

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11
Q

T/F: “washdown” is damaging to the body.

A

False; protects the body

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12
Q

T/F: as we increase interstitial fluid pressure, lymph flow increases which results in a decrease in interstitium protein concentration.

A

True

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13
Q

T/F: a decrease in interstitium protein concentration decreases the osmotic pressure.

A

True

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14
Q

T/F: The negative hydrostatic pressure of interstitial fluid in loose subcutaneous tissues, increased lymph flow, and washdown of proteins are all safety factors that increase edema.

A

False; these are safety factors that prevent edema

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15
Q

T/F: Kidneys are located in the retroperitoneal space and around the L1-L4 vertebra.

A

True

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16
Q

Where are the cortex and medulla?

A

Cortex is outer; you should look at a picture if you don’t know

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17
Q

How many renal pyramids are in the medulla of each kidney?

A

8-10; know the major/minor calyces

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18
Q

T/F: Calyces, renal pelvis, and ureter all contract to propel urine to the bladder,

A

True

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19
Q

How much of the cardiac output is kidney blood flow?

A

22% (1100 ml/min on avg)

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20
Q

What is the order of Kidney blood flow beginning with the renal artery going in?

A

Renal artery->interlobar arteries -> arcuate arteries -> interlobar arterioles-> afferent arterioles -> Glomerular capillaries -> Efferent arteriole -> Peritubular capillaries

RIA In A GEP

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21
Q

What is unique about kidney blood flow?

A

there are two capillary beds

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22
Q

What are the two capillary beds of the kidneys?

A

glomerular and peritubular capillaries

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23
Q

Which have higher hydrostatic pressure, glomerular or peritubular capillaries?

A

glomerular capillaries

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24
Q

Which causes rapid fluid filtration, glomerular or peritubular capillaries?

A

glomerular capillaries

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25
Q

Which allows for rapid fluid reabsorption, glomerular or peritubular capillaries?

A

peritubular capillaries

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26
Q

What is the order of kidney blood flow going out beginning with the peritubular capillaries?

A

peritubular caps -> interlobar vein -> arcuate vein -> interlobular vein -> renal vein

PI AIR

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27
Q

What is the functional unit of the kidney>

A

nephron

28
Q

Be able to label that diagram in the notes around the nephron material.

A

Especially, Afferent arteriole from the renal artery, glomerulus, Bowman’s capsule, Proximal tubule, Peritubular capillaries, Distal tubule, Collecting duct, Loop of Henle, and the efferent areteriole from glomerulus

29
Q

T/F: The kidney cannot regenerate new nephrons.

A

true

30
Q

T/F: After 40 years old, there is a decrease of fxn nephrons of 10% every 10 years.

A

True

31
Q

What capillaries are encased in Bowman’s capsule?

A

Glomerular capillaries

32
Q

What is the order of fluid filtered from the glomerular capillaries?

A

Bowman’s capsule, proximal tubule, loop of Henle, macula densa, distal tubule, connecting tubule, cortical collecting duct, medullary collecting duct, and finally, renal pelvis through tips of the renal papillae.

33
Q

What are the 2 different structural types of nephron?

A

cortical nephron, and juxtamedullary nephron

34
Q

Which structural type of nephron are the short loops of Henle? long loops of Henle?

A

short-Cortical
Long-Juxtamedullary
(Juxtamedullary is a longer word than cortical)

35
Q

T/F: Most nephrons are juxtamedullary nephrons.

A

False; 20-30% are juxtamedullary, 70-80% are cortical

36
Q

What condition is caused by different disorders that damage the kidney, causing release of excess proteins in the urine?

A

Nephrotic Syndrome

37
Q

Along with protein in the urine, what other sign is associated with Nephrotic Syndrome?

A

Foamy urine

38
Q

With Nephrotic Syndrome, what is the MC protein found in the urine?

A

Albumin

39
Q

T/F: UTIs caused by bacterial infection are commonly associated with Cystitis.

A

True

40
Q

What condition is characterized by an acute infection of the renal pelvis or pernchyma usually due to an ascendin infection (UTI)?

A

Pyelonephritis

41
Q

What is the condition that commonly causes kidney stones?

A

Nephrolithiasis

42
Q

What are the MC types of kidney stones?

A

calcium oxilate or calcium phosphate

43
Q

T/F: Predisposition to having kidney stones runs in families.,

A

True

44
Q

What is PKD?

A

Polycystic kidney disease - a genetic disorder that causes formation and enlargement of cysts in the kidneys

45
Q

T/F: The micturition reflex is a nervous reflex that occurs after tension of the bladder wall raises above a threshold level.

A

True

46
Q

What is the important muscle associated with the bladder?

A

detrusor muscle

47
Q

T/F: the detrusor muscle is smooth muscle and its fibers are intertwined.

A

True

48
Q

T/F: the detrusor muscle has a high-resistance to electrical impulse between muscle cells.

A

False; low-resistance which is why the whole bladder empties at once

49
Q

What is the structure located on the posterior wall of the bladder, above the bladder neck?

A

trigone

50
Q

What is noticeably different about the trigone of the bladder?

A

It is smooth; the rest is folded

51
Q

T/F: the tone of the detrusor shuts down the ureters and prevents backflow of urine.

A

True

52
Q

What muscle is located in the neck of the bladder and is composed of the detrusor muscle and elastic tissue?

A

internal sphincter

53
Q

What muscles prevents emptying of the bladder until the pressure rises above the critical threshold?

A

internal sphincter

54
Q

T/F: the urethra passes through the urogenital diaphragm.

A

True

55
Q

T/F: the external sphincter muscles is smooth muscle and under voluntary control.

A

True

56
Q

What is the innervation of the bladder?

A

pelvic nerves through the sacral plexus (S2, S3 cord segments)

57
Q

What nerve innervates the external bladder sphincter?

A

Pudendal nerve

58
Q

T/F: Urine flows from the nephron to the collecting ducts to the renal calyces to the ureters to the bladder.

A

True

59
Q

T/F: Urine flow from the collecting ducts to the renal calyces causes peristaltic contractions.

A

True

60
Q

What causes the micturition reflex?

A

sensory stretch receptors are initiated as the bladder fills with urine

61
Q

T/F: the micturition reflex is regenerative.

A

True, the cycle repeats multiple times

62
Q

T/F: if the bladder is not emptied, the micturition reflex can be inhibited for minutes or even hours.

A

True

63
Q

T/F: the micturition reflex is an autonomic reflex.

A

True

64
Q

What part of the brain can inhibit or facilitate urination?

A

centers in the pons and cerebral cortex

65
Q

What has the final control of micturition?

A

higher centers (pons and cerebral cortex)

66
Q

How can urination be voluntary?

A

When a person contracts the abdominal muscles it increases the pressure in the bladder which stimulates stretch receptors.