Exam 1; Neoplasia I

Question 1

This type of neoplasm remains localized, cannot spread to other sites, generally amenable to surgical removal and patient survival

Answer 1

benign neoplasm

Question 2

This type of neoplasm has the potential to invade and destroy adjacent normal tissue and spread to distant anatomic sites. Often leads to death of the patient especially without treatment

Answer 2

malignant neoplasm

Question 3

This refers to the transformed or neoclassic cells; the parenchymal component determines the biologic behavior of the particular neoplasm, and it is this component from which the neoplasm derives its name

Answer 3

parenchyma

Question 4

This refers to the supporting tissue of the tumor - the non-neoplastic blood vessels and connective tissue supplied by the host

Answer 4

stroma

Question 5

Which suffix is worse -oma or -sarcoma

Answer 5

• sarcoma; thats used for malignant

- oma; used for benign

Question 6

What are malignancies of epithelial origin called

Answer 6

carcinomas

Question 7

This refers to the degree to which the parenchymal tissue or a neoplasm resembles the parent tissue, both functionally and morphologically

Answer 7

differentiation and anaplasia

Question 8

What is meant by that benign neoplasms are generally well defined

Answer 8

the parenchymal cells bear a strong resemblance to the tissue from which the tumor arose

Question 9

Malignancies composed of poorly differentiated cells are described as what

Answer 9

anaplastic

Question 10

This is characterized by pleomorphism, nuclear hyperchromatism, an increased nuclear/cytoplasmic ratio compared to normal cells, atypical nuclei, and numerous and atypical mitoses

Answer 10

anaplasia

Question 11

This refers to an altered growth pattern, usually referring to epithelium that is not neoplastic but may become cancerous eventually

Answer 11

dysplasia

Question 12

The most severe epithelial dysplasia is referred to as what, it as all the microscopic features of cancer, but the atypical cells have not invaded into the host

Answer 12

carcinoma-in-situ

Question 13

the better the degree of differentiation of a neoplasm, the more it does what

Answer 13

completely retains the functional capabilities of the tissue from which it arose

Question 14

Benign tumors generally grow fast or slowly

Answer 14

slowly

Question 15

What is the growth rate of malignant neoplasms

Answer 15

highly variable; depends on the type of tumor

some may grow so quickly that they outgrow the blood supply which would explain necrosis

Question 16

Benign tumors tend to have this, which is essentially a compressed band of fibrous connective tissue at the periphery of the tumor

Answer 16

a capsule

Question 17

What are the three ways in which cancers grow

Answer 17

progressive infiltration
invasion
destruction and penetration

Question 18

This quality is the most reliable means for distinguishing the malignant nature of a tumor

Answer 18

infiltrative quality

Question 19

What is the best indicator of a malignancy

Answer 19

the presence of metastasis