Exam 1 Meds: Unique & SE Flashcards
Aripiprazole
Unique:
Low risk metabolic SE
AKATHESIA common
Possibly help Pos & Neg
symptoms
SE:
Akathesia
Insomnia
N/V
HA
Brexpiprazole
Unique:
Like abilify…
Agitation in alz?
SE:
Akathesia
Anxiety
TD
Cariprazine
Unique:
Akathesia common
D3 antag - improv negative, affective, & cognitive symptoms
Long-half life
SE:
Akathesia
GI distress
Sedation
Clozapine
Unique:
Agranulocytosis! Blood work*
Seizure risk
Myocardidtis
Gold standard for SHCZ efficacy
SE:
Weight
Sedation
Drooling/Anticholinergic
Paralytic Ileus!
Haloperidol
Unique:
Motor SE common… high limit for dosing
SE:
EPS
TD
Neuroleptic induced deficit syndrome
Akathesia
PRL inc
Weight
Lurasidone
Unique:
Great metabolic SE profile*
Must eat with 300/cal food
SE:
Akathesia
Nausea
Sedation
Olanzapine
Unique:
Big metabolic SE*
SE:
Weight gain/Metabolic
DM
Sedation
Risperidone
Unique:
PRL increase common
SE:
EPS
Weight
PRL
Sedation
Ziprasidone
Unique:
Requires food intake w/ med (300cal)
Minimal weight/metabolic SE
QT prolongation**
SE:
Sedation
Activation
Nausea
Orthostatic HTN
TD
Sertraline
Unique:
Take with food
SE:
GI
Sexual
Insomnia
Fluoxetine
Unique:
Activation
Long half-life
Inhibitor CYP450
Bullimia FDA approval
SE:
Activating
GI distress
Sexual
Paroxetine
Unique:
Poor SE profile
DC syndrome
Teratogenic
SE:
Weight gain
Sexual
Citalopram
Unique:
Qt Prolongation*
SE:
Nausea
Escitalopram
Unique:
Good SE profile
Low/no drug interactions*
SE:
Nausea
HA
Sexual
Fluvoxamine
Unique:
CYP inhibitor (drug interactions)
Anxiolytic? (sigma 1 antag)
OCD approval only
SE:
Weight
sexual?
Drug interactions
