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PTH 507: ORTHO > Exam 1: MEDS > Flashcards

Exam 1: MEDS Flashcards

1
Q

NSAIDs MOA

A
  • interfere with biosynthesis of prostaglandins. (too many prostaglandins inc sensitivity of pain)
  • COX inhibitors
  • Selective (COX-1 and -2) and non-selective
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2
Q

Side effect of NSAIDs

A

-GI

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3
Q

Motrin

A
  • Ibuprofen

- NSAID

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4
Q

codeine

A

opioid

-analgesic

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5
Q

Toradol

A
  • ketorolac tromethamine

- NSAID

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7
Q

feldene

A
  • piroxicam

- NSAID

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8
Q

Opioids - MOA

A
  • analgesic
  • inhibit synaptic transmission by dec neurotransmitter release from the presynaptic terminal and dec the excitability of the postsynaptic neuron within key pain pathways in the spinal cord and brain
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9
Q

adverse opioid side effects

A

-sedation, euphoria, slower respiratory rate, orthostatic hypotension, GI, addition?

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10
Q

Morphine

A
  • opioid

- analgesic

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11
Q

Demerol

A
  • meperidine
  • opioid
  • analgesic
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12
Q

hydrocodone

A
  • hycodan
  • opioid
  • analgesic
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13
Q

oxycodone

A
  • OxyContin
  • opioid
  • analgesic
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14
Q

Voltaren

A
  • diclofenac

- NSAID

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14
Q

Relafen

A
  • nabumetone

- NSAID

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15
Q

darvon/darvocet

A
  • propoxyphene
  • opioid
  • analgesic
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16
Q

Acetaminophen (type, what they do, examples)

A
  • analgesic
  • not anti-inflammatory or anti-coagulation effects
  • excedrin and tylenol
17
Q

Valium (name, MOA, group, side effects)

A
  • diazepam
  • muscle relaxant
  • MOA: inc inhibitory effects of GABA on alpha motor neuron activity in spinal cord

-adverse effects: sedation, tolerance and dependence

18
Q

Polysynaptic inhibitors (MOA, Side effects)

A
  • muscle relaxants
  • MOA: not well defined. dec activity in polysynaptic pathways that lead to the alpha motorneuron. also cause global dec in CNS excitability

-Side effects: sedation, nausea, light headedness, vertigo, headache

19
Q

Flexeril

A
  • chlorzoxazone

- polysynaptic inhib (muscle relaxant)

20
Q

Paraflex/parafon forte

A
  • chlorzaxazone

- polysynaptic inhib (muscle relaxant)

21
Q

skelaxin

A
  • metaxalone

- polysynaptic inhib (muscle relaxant)

22
Q

Soma

A
  • carisoprodol

- polysynaptic inhib (muscle relaxant)

23
Q

Steriods - oral and injection. Glucocorticoids MOA

A

-inhibit the transcription and expression of adhesion molecules which are responsible for attracting leukocytes to endothelial cells at the side of inflammation

24
Q

Glucocorticoids - side effects

A
  • renal function, general catabolic effect on muscles, bone, ligament, and tendon with chronic use.
  • injections usually limited to max 3

PTH 507: ORTHO (4 decks)

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