exam 1 lecture 9 - 10 sympatholytics Flashcards
1
Q
nonselective a antagonist
A
blocks NE binding
b-haloalkylamines + immidazolines
2
Q
b-haloalylamines
A
alkyl-chain causes irreversible antagonism bc covalent bond
nonselective a antagonist: phenoxybenzamine
3
Q
immidazoline
A
reversible blocker (potent vasodilator)
phentolamine
nonselective a antagonist
4
Q
A1 receptor antaonist
A
quinazolines “zosins”: vaosdilators + relaxation of smooth muscle in enlarge prostate
prazosin, terazosin, doxazosin, tamsulosin
5
Q
prazosin
A
vasodilator
clinical use: HTN, reynauds, BPH
6
Q
tamsulosin
A
BPH
a1 antagonist in prostate
a1 in prostate contractions –> this antagonist
7
Q
yohimbine
A
A2 antagonist
8
Q
Nonselective b-blockers
A
“olol” propranolol, nadelol, timolol, pindolol, careolol
