controller medications asthma + COPD Flashcards

1
Q

beclomethasone

A

ICS
QVAR
redihaler (metered dose inhaler - MDI)
5-11, adult

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2
Q

budesonide

A

ICS
pulmicort
flexhaler
5-11, adult

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3
Q

budesonide respules

A

ICS
pulmicort respulses
nebuilzer solution
0-4, 5-11

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4
Q

ciclesonide

A

ICS
alvesco
HFA
5-11, adult

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5
Q

fluticasone propionate

A

ICS
flovent, armonair digihaler
HFA, DPI (dry powder inhalation), aerosol powder inhaler
0-4, 5-11, adult

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6
Q

fluticasone furoate

A

ICS
arnuity elipta
elipta
5-11, adult

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7
Q

mometasone

A

ICS
asmanex
HFA, Twisthaler
5-adult

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8
Q

arformoterol tartrate

A

LABA
brovana
nebulizer solution
adult COPD

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9
Q

formeterol

A

LABA
perforomist
nebulizer
adult

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10
Q

indacaterol

A

LABA
arcapta neohaler
neohaler
adult

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11
Q

olodaterol

A

LABA
striverdi respimat
respimat
adult

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12
Q

salmeterol

A

LABA
serevent
diskus
5-11, adult

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13
Q

aclidinium

A

LAMA
turdoza pressair
DPI (dry powder inhalation)
adult

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14
Q

glycopyrrolate

A

LAMA
seebri neohaler
DPI, nebulizer solution
adult

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15
Q

revefenacin

A

LAMA
yupelri
nebulizer solution
adult

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16
Q

tiotropium

A

LAMA
spiriva
handihaler 6-adult, respimat adult
COPD

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17
Q

umeclidinium

A

LAMA
incruse elipta
DPI
adult COPD

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18
Q

fluticasone/salmeterol

A

ICS/LABA
advair
DPI, HFA MDI
5-11, adult

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19
Q

fluticasone/salmeterol

A

ICS/LABA
airduo + airduo digihaler
respiclick (DPI)
adult

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20
Q

budesonide/formoterol

A

ICS/LABA
symbicort
HFA MDI
5-11, adult

21
Q

mometasone/formoterol

A

ICS/LABA
dulera
MDI
adult

22
Q

fluticasone/vilanterol

A

ICS/LABA
breo elipta
DPI
adult

23
Q

olodaterol/tiotropium

A

LABA/LAMA
stiolto respimat
respimat DPI
adult COPD

24
Q

vilanterol/umeclidnium

A

LABA/LAMA
anoro elipta
elipta DPI
adult COPD

25
indacaterol/glycopyrronium
LABA/LAMA utibron neohaler neohaler DPI adult COPD
26
formoterol/glycopyrronium
LABA/LAMA bevespi aerosphere aerosphere DPI adult COPD
27
formoterol/aclidinium
LABA/LAMA duaklir pressair DPI adult COPD
28
fluticasone/umeclidnium/vilanterol
LABA/LAMA/ICS trelegy elipta DPI adult COPD + asthma
29
budesonide/glycopyrolate/formoterol fumarate
LABA/LAMA/ICS beztri aerosphere aerosphere adult COPD
30
cromolyn
mast cell stabilizer intal nebulizer 0-adult
31
montelukast
leukotriene modifiers singulair tablets, granule packets 0-adult
32
zafirlukast
luekotriene modifiers accolate tabs 5-adult
33
zileuton
luekotriene modifiers zyflo tabs adult
34
theophylline
methylxanthines theochron tabs + liquid adult similar to caffeine sides: tremor, GI upset, hypotension
35
omalizumab
anti-IgE xolair syringe 5-adult
36
mepolizumab
anti-IL5 nucala autoinjector 6-adult headache, herpes zoster infection
37
relizumab
anti-IL5 cinqair injection 18+
38
benralizumab
anti-IL5 fasenra injection adult at home injection or at clinic
39
dupilumab
anti-IL4/IL13 dupixent injection adult mod to severe asthma 12+
40
roflumilast
PDE4 inhibitor daliresp tabs adult COPD only AE: HA, weightless, diarrhea, nausea
41
ICS
prevent + control inflammation AE: oral thrush, cough, dysphoria counseling tips: wash mouth, risk of pneumonia, best therapy for controlling asthma
42
LABA
increase cAMP --> bronchial relaxation and decrease sensitivity to mast cell mediators AE: tachycardia, headache, tremor, hypoalkemia Box warning: increase risk of death for LABA monotherapy, increased hospitalizations in PEDS counseling: not for acute symptoms, prolonged QT interval
43
LAMA
block acetylcholine on M3 and M2 receptors AE: dry mouth, dizziness, blurred vision, upper respiratory infection, paradoxical bronchospams tiotropium approved for asthma in less than 12
44
mast cell stabilizers
prevent mast cell degranulation
45
leukotriene modifiers
block leukotriene production (chronic + allergic inflammation) neuropsychiatric events (depression, anxiety, bad dreams)
46
methylxanthines
bronchodilation by inhibition PDE3 + PDE4 AE: insomnia, GI upset, hypotension, tremor Toxicity: tachycardia, nausea, vomiting, headache CI: peptic ulcer disease, arrhythmias, seizure disorder
47
Anti-IgE
inhibit IgE binding to receptors on mast cells and basophils --> inhibits mediator release for late + early phase allergic response
48
anti-IL5
blocks binding of IL5 to alpha chain on IL5 receptor complex --> reduce production + survival of eosinophils