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825 therapuetics > controller medications asthma + COPD > Flashcards

controller medications asthma + COPD Flashcards

1
Q

beclomethasone

A

ICS
QVAR
redihaler (metered dose inhaler - MDI)
5-11, adult

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2
Q

budesonide

A

ICS
pulmicort
flexhaler
5-11, adult

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3
Q

budesonide respules

A

ICS
pulmicort respulses
nebuilzer solution
0-4, 5-11

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4
Q

ciclesonide

A

ICS
alvesco
HFA
5-11, adult

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5
Q

fluticasone propionate

A

ICS
flovent, armonair digihaler
HFA, DPI (dry powder inhalation), aerosol powder inhaler
0-4, 5-11, adult

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6
Q

fluticasone furoate

A

ICS
arnuity elipta
elipta
5-11, adult

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7
Q

mometasone

A

ICS
asmanex
HFA, Twisthaler
5-adult

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8
Q

arformoterol tartrate

A

LABA
brovana
nebulizer solution
adult COPD

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9
Q

formeterol

A

LABA
perforomist
nebulizer
adult

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10
Q

indacaterol

A

LABA
arcapta neohaler
neohaler
adult

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11
Q

olodaterol

A

LABA
striverdi respimat
respimat
adult

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12
Q

salmeterol

A

LABA
serevent
diskus
5-11, adult

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13
Q

aclidinium

A

LAMA
turdoza pressair
DPI (dry powder inhalation)
adult

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14
Q

glycopyrrolate

A

LAMA
seebri neohaler
DPI, nebulizer solution
adult

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15
Q

revefenacin

A

LAMA
yupelri
nebulizer solution
adult

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16
Q

tiotropium

A

LAMA
spiriva
handihaler 6-adult, respimat adult
COPD

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17
Q

umeclidinium

A

LAMA
incruse elipta
DPI
adult COPD

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18
Q

fluticasone/salmeterol

A

ICS/LABA
advair
DPI, HFA MDI
5-11, adult

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19
Q

fluticasone/salmeterol

A

ICS/LABA
airduo + airduo digihaler
respiclick (DPI)
adult

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20
Q

budesonide/formoterol

A

ICS/LABA
symbicort
HFA MDI
5-11, adult

21
Q

mometasone/formoterol

A

ICS/LABA
dulera
MDI
adult

22
Q

fluticasone/vilanterol

A

ICS/LABA
breo elipta
DPI
adult

23
Q

olodaterol/tiotropium

A

LABA/LAMA
stiolto respimat
respimat DPI
adult COPD

24
Q

vilanterol/umeclidnium

A

LABA/LAMA
anoro elipta
elipta DPI
adult COPD

25
Q

indacaterol/glycopyrronium

A

LABA/LAMA
utibron neohaler
neohaler DPI
adult COPD

26
Q

formoterol/glycopyrronium

A

LABA/LAMA
bevespi aerosphere
aerosphere DPI
adult COPD

27
Q

formoterol/aclidinium

A

LABA/LAMA
duaklir pressair
DPI
adult COPD

28
Q

fluticasone/umeclidnium/vilanterol

A

LABA/LAMA/ICS
trelegy elipta
DPI
adult COPD + asthma

29
Q

budesonide/glycopyrolate/formoterol fumarate

A

LABA/LAMA/ICS
beztri aerosphere
aerosphere
adult COPD

30
Q

cromolyn

A

mast cell stabilizer
intal
nebulizer
0-adult

31
Q

montelukast

A

leukotriene modifiers
singulair
tablets, granule packets
0-adult

32
Q

zafirlukast

A

luekotriene modifiers
accolate
tabs
5-adult

33
Q

zileuton

A

luekotriene modifiers
zyflo
tabs
adult

34
Q

theophylline

A

methylxanthines
theochron
tabs + liquid
adult
similar to caffeine sides: tremor, GI upset, hypotension

35
Q

omalizumab

A

anti-IgE
xolair
syringe
5-adult

36
Q

mepolizumab

A

anti-IL5
nucala
autoinjector
6-adult
headache, herpes zoster infection

37
Q

relizumab

A

anti-IL5
cinqair
injection
18+

38
Q

benralizumab

A

anti-IL5
fasenra
injection
adult
at home injection or at clinic

39
Q

dupilumab

A

anti-IL4/IL13
dupixent
injection
adult
mod to severe asthma 12+

40
Q

roflumilast

A

PDE4 inhibitor
daliresp
tabs
adult COPD only
AE: HA, weightless, diarrhea, nausea

41
Q

ICS

A

prevent + control inflammation
AE: oral thrush, cough, dysphoria
counseling tips: wash mouth, risk of pneumonia, best therapy for controlling asthma

42
Q

LABA

A

increase cAMP –> bronchial relaxation and decrease sensitivity to mast cell mediators
AE: tachycardia, headache, tremor, hypoalkemia
Box warning: increase risk of death for LABA monotherapy, increased hospitalizations in PEDS
counseling: not for acute symptoms, prolonged QT interval

43
Q

LAMA

A

block acetylcholine on M3 and M2 receptors
AE: dry mouth, dizziness, blurred vision, upper respiratory infection, paradoxical bronchospams
tiotropium approved for asthma in less than 12

44
Q

mast cell stabilizers

A

prevent mast cell degranulation

45
Q

leukotriene modifiers

A

block leukotriene production (chronic + allergic inflammation)
neuropsychiatric events (depression, anxiety, bad dreams)

46
Q

methylxanthines

A

bronchodilation by inhibition PDE3 + PDE4
AE: insomnia, GI upset, hypotension, tremor
Toxicity: tachycardia, nausea, vomiting, headache
CI: peptic ulcer disease, arrhythmias, seizure disorder

47
Q

Anti-IgE

A

inhibit IgE binding to receptors on mast cells and basophils –> inhibits mediator release for late + early phase allergic response

48
Q

anti-IL5

A

blocks binding of IL5 to alpha chain on IL5 receptor complex –> reduce production + survival of eosinophils

825 therapuetics (8 decks)

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