Exam 1: lecture 5 Flashcards
Types of passive transport
no energy required
1) osmosis: water
2) simple diffusion: small molecules (gases: CO2& O2, H20)
3) ion channel diffusion (Cl- HCO3-)
4) facilitated carrier diffusion (glucose)
Rules of membrane diffusion
size rule- small molecules get past
charge rule- no charged molecules get past
polarity rule-nonpolar molecules (hydrophic) get past wile polar molecule do not
summary of relative permeabilities
hydrophobic molecule: O2, CO2, N2 (size and polarity)
small, uncharged polar molecules (h2o, glycerol)
large, uncharged polar molecules (glucose, sucrose)
ions (h+, Na+, ca2+)
fluidity
allows membrane to adapts its shapes and movement to different condition
permeability
the rate of diffusion-only selected ones
what changes the fluidity and permeablity of membranes
kinks
bilayer with saturated fatty acids have LOW permeability
bilayer with unsaturated fatty acid have HIGh permeability
what does cholesterol do in membranes
fill spaces between phospholipids
*the more cholesterol in the membrane, the less permeable it is
cholesterol membrane paradox
cholesterol increases the fluidity but decreases permeability (water) because it causes the membrane to become more hydrophobic
***cholesterol up, fluidity up, permeability down (harder to get across due to it being more nonpolar)