Exam 1: lecture 3 Flashcards
what is a virus
1)NOT alive
why?
not respire
cannot live on their own (need host)
2)have an RNA/DNA genome encased in special protective coat=capsid (glycoprotein/ lipoprotein)
3) cannot reproduce wo being inside a host cell
4) do not respond to antibiotics- antivirals
5) replication is dependent on taking over the genetic machinery of a cell and subverting it
6) species specific
=Molecular parasites
How are viruses characterized?
-shape
-their host
-their genome
-size
-method of reproduction
-immunological characteristics
-flulike symptoms
1 micrometer
1/ 1 millionth meters
1 nanometer
1/1 billionth meter
10^-9
basic viral structures: non-enveloped virus
dna
capsomeres (protein units)
capsid (protein coat)-protective genetic info
fiber: binding+ recognition
basic viral structures: envelopedvirus
rna
capsid(protein coat)
envelope-made up of lipids+ proteins
spike : allow recognition
bacteriophages
attack bacteria
Lytic cycle
virus uses the host cells to reproduce
- attachment: capsid combines with receptor
- penetration: viral DNA enter host
3: biosynthesis: viral components are synthesized
4: maturation - new viruses leave host cell
lysogenic cycle
virus dna is incorporated into the host genome and stays there until the lytic cycle is triggered
-this cycle happens bc there is not sufficient materials to reproduce
prions
hyperstable protein- not a virus