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Pharmacotherapy IV > Exam 1 GI Memorization > Flashcards

Exam 1 GI Memorization Flashcards

1
Q

OTC dose of cimetidine

A

200mg BID

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2
Q

OTC dose of famotidine

A

10mg BID

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3
Q

OTC dose of nizatidine

A

75mg BID

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4
Q

OTC dose of ranitidine

A

75mg BID

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5
Q

Nonerosive GERD dose of cimetidine

A

400mg BID

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6
Q

Nonerosive GERD dose of famotidine

A

20mg BID

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7
Q

Nonerosive GERD dose of nizatidine

A

150mg BID

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8
Q

Nonerosive GERD dose of ranitidine

A

150mg BID

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9
Q

OTC dose of esomeprazole

A

20mg daily x 14 days every 4 months

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10
Q

OTC dose of lansoprazole

A

14mg daily x 14 days every 4 months

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11
Q

OTC dose of omeprazole

A

20mg daily x 14 days every 4 months

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12
Q

OTC dose of omeprazole + sodium bicarbonate

A

20mg/1100mg daily x 14 days every 4 months

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13
Q

Nonerosive/maintenance dose of dexlansoprazole

A

30mg daily

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14
Q

Nonerosive/maintenance dose of esomeprazole

A

20mg daily

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15
Q

Nonerosive/maintenance dose of lansoprazole

A

15-30mg daily

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16
Q

Nonerosive/maintenance dose of omeprazole

A

20mg daily

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17
Q

Nonerosive/maintenance dose of pantoprazole

A

40mg daily

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18
Q

Nonerosive/maintenance dose of rabeprazole

A

20mg daily

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19
Q

Nonerosive/maintenance dose of omeprazole + sodium bicarbonate

A

20mg/1100mg daily

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20
Q

Erosive GERD dose of dexlansoprazole

A

60mg daily

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21
Q

Erosive GERD dose of esomeprazole

A

40mg daily

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22
Q

Erosive GERD dose of lansoprazole

A

30mg BID

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23
Q

Erosive GERD dose of omeprazole

A

20mg BID

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24
Q

Erosive GERD dose of pantoprazole

A

40mg BID

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25
Q

Erosive GERD dose of rabeprazole

A

20mg BID

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26
Q

Erosive GERD dose of omeprazole + sodium bicarbonate

A

20mg/1100mg daily

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27
Q

What PPIs are available IV?

A

Pantoprazole and esomeprazole

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28
Q

What PPI is available as ODT?

A

Lansoprazole

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29
Q

Which PPIs may not be crushed?

A

Pantoprazole, rabeprazole

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30
Q

Which PPIs may be opened and dissolved in applesauce or water?

A

Omeprazole, esomeprazole, lansoprazole, and dexlansoprazole

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31
Q

Dose of docusate?

A

100mg daily or BID

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32
Q

Dose of sorbitol for constipation?

A

30-60mL daily

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33
Q

Dose of lactulose for constipation?

A

30-60mL daily

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34
Q

Dose of PEG for constipation?

A

17g dissolved in 4-8oz fluid daily

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35
Q

Dose of senna for constipation?

A

2 tablets 1-2 times daily

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36
Q

Dose of bisacodyl for constipation?

A

1-2 tablets daily

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37
Q

Dose of castor oil for constipation?

A

30-60mL daily

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38
Q

Dose of bisacodyl suppository?

A

10mg daily PR

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39
Q

Dose of lubiprostone for constipation?

A

24mcg BID with food

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40
Q

Dose of linaclotide for constipation?

A

145mcg daily 30 minutes before 1st meal of the day

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41
Q

Dose of methylnaltrexone?

A

8-12mg SC QOD

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42
Q

Dose of naloxegol?

A

25mg PO daily

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43
Q

Dose of loperamide?

A

4mg PO initially, then 2mg after each loose stool. NTE 16mg per day

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44
Q

Dose of diphenoxylate/atropine?

A

5mg (2 tablets) 4x daily, NTE 20mg per day.

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45
Q

Dose of difenoxin/atropine?

A

2mg (2 tabs) initially, then 1 with each loose stool, NTE 8 tabs daily

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46
Q

Dose of pepto-bismol for diarrhea?

A

2 tablets or 30mL q30-60minutes prn, up to 8 doses per day.

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47
Q

Dose of linaclotide for IBS-C?

A

290mcg daily on empty stomach 30 min before 1st meal of day

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48
Q

Dose of lubiprostone for IBS-C?

A

8mcg BID

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49
Q

Dose of dicyclomine for IBS?

A

20-40mg PO q6h, 30-60 min before meals

50
Q

Dose of hyoscyamine for IBS?

A

0.125-0.25mg PO/SL q4h prn (MAX 1.5mg/day)

51
Q

Dose of rifaximin for IBS-D?

A

550mg TID x 14 days

52
Q

Dose of eluxadoline for IBS?

A

75-100mg BID with food

53
Q

How is lorazepam dosed for prevention of acute CINV in high emetic risk?

A

0.5-2mg IV or PO q4-6h prn days 1-4

54
Q

How is olanzapine dosed for prevention of acute CINV in high emetic risk?

A

10mg PO on days 1-4

55
Q

How is dexamethasone dosed for prevention of acute CINV in high emetic risk?

A

12mg I/PO on day 1, then 8mg daily on days 2-4 (can be up to 12mg or BID)

56
Q

How is palonosetron dosed for prevention acute CINV (in regimens excluding netupitant) in high emetic risk?

A

0.25mg IV on day 1

57
Q

How is palonosetron dosed for prevention of acute CINV in a regimen including netupitant in high emetic risk?

A

0.5mg IV on day 1

58
Q

How is budesonide to induce UC remission?

A

6-8mg/day for up to 8 week

59
Q

How is prednisone dosed to induce UC remission?

A

40-60mg PO daily, taper 5-10mg/week until dose of 20mg/day is reached, then taper 2.5mg/week

60
Q

How is Solu-Merol dosed to induce UC remission?

A

16-20mg q6h

61
Q

How is Solu-Cortef dosed to induce UC remission?

A

100mg q8h

62
Q

Azathioprine dose for IBD?

A

0.5-1.5mg/kg IBW, may increase to max of 2.5mg/kg/day

63
Q

Mercaptopurine dose for IBD?

A

0.25-0.5mg/kg IBW, increase to max of 1-1.5mg/kg/day

64
Q

Methotrexate dose for CD?

A

15-25mg SC/IM weekly

65
Q

Cyclosporine dose for UC?

A

2-4mg/kg/day IV, double the IV dose for PO, divide BID

66
Q

Infliximab dose for UC/CD?

A

5mg/kg IV infusion over 2 hours at 0, 2, 6, then q8weeks. May increase to 10mg/kg q8.

67
Q

Adalimumab dose for UC/CD?

A

160mg SQ at week 0, 80mg at week 2, then 40mg QOW after

68
Q

Golimumab dose for UC?

A

200mg SQ at week 0, 100mg week 2, 100mg q4w after

69
Q

Certolizumab pegol dose for CD?

A

400mg SQ at week 0, 2, 4 then 400mg q4weeks

70
Q

Natalizumab dose for CD?

A

300mg IV infusion over 1 hour q4 week

71
Q

What is the bedside schwartz equation for calculating GFR in pediatric patients?

A

0.413 x height in cm / SCr = mL/min per 1.73 m^2

72
Q

Pediatric dose of ranitidine IV and oral?

A

IV: 1-2mg/kg q8-12h (MAX 300mg)
PO: 4-8 mg/kg/day divided BID

73
Q

Pediatric dose of famotidine IV and oral?

A

IV: 0.5mg/kg 1-2 times daily (MAX 40mg)
PO: 1mg/kg/day divided BID (MAX 40mg)
Used 3months-12yo

74
Q

Pediatric dose of lansoprazole?

A

1mg/kg/day in infants in children

75
Q

Pediatric dose of omeprazole?

A

~1mg/kg/day in infants and children.

76
Q

Dose of PEG for pediatric disimpaction?

A

1-1.5g/kg/day x 3-6 days

77
Q

Dose of mag citrate for pediatric disimpaction?

A

4mL/kg/day x 2 consecutive days

78
Q

Dose of PEG for pediatric maintenance?

A

1g/kg/day

79
Q

Docusate dose for pediatric constipation prevention?

A

5mg/kg/day (up to 400mg/day)

80
Q

Octreotide dose for acute variceal bleeding?

A

50-100mcg IV bolus then 25-50mcg/hr infusion x1-3 days

81
Q

Esomeprazole or pantoprazole dose for variceal bleeding?

A

Initial 80mg IV load then 8mg/hr infusion x 3-5 days, then high dose x 4 weeks

82
Q

How should you start propranolol post variceal bleed?

A

10mg BId or TID, titrate to BP and HR tolerance

83
Q

How should you start nadolol post variceal bleed?

A

20mg daily, titrate to HR/BP, adjust for renal failure

84
Q

How is albumin dosed after therapeutic paracentesis?

A

If removed volume is >5L, give albumin at 8gm/L of ascitic fluid

85
Q

Metronidazole dose to prevent hepatic encephalopathy?

A

250mg PO q6-12h

86
Q

Lactulose dose to treat then prevent hepatic encephalopathy?

A

Initial: 45mL/hr until catharsis

15-45mL q8-12h, titrate to 3-4 soft bowel movements daily

87
Q

Neomycin dose for HE prevention?

A

3-6g/day (divided doses)

88
Q

Rifaximin dose for HE?

A

Treatment: 400mg q8h x5-10 days
Prevention: 550mg BID

89
Q

Famotidine dose for SRMD prophylaxis?

A

PO: 20mg BID
IV intermittent: 20mg BID
IV continuous: 1.7mg/hr

90
Q

Ranitidine dose for SRMD prophylaxis?

A

PO: 150mg BID
IV intermittent: 50mg q6-8h
IV continuous: 6.25mg/hr

91
Q

Cimetidine dose for SRMD prophylaxis?

A

300mg QID PO

92
Q

Cimetidine dose for active ulcer?

A

800mg at bedtime
400mg BID
300mg QID

93
Q

Cimetidine dose for PUD maintenance?

A

400-800mg at bedtime

94
Q

Famotidine dose for active ulcer?

A

40mg at bedtime

20mg BID

95
Q

Famotidine PUD maintenance dose?

A

20-40mg at bedtime

96
Q

Nizatidine dose for active ulcer?

A

300mg at bedtime

150mg BID

97
Q

Nizatidine dose for PUD maintenance?

A

150-300mg at bedtime

98
Q

Ranitidine dose for active ulcer?

A

300mg at bedtime

150mg BID

99
Q

Ranitidine dose for PUD maintenance?

A

150-300mg at bedtime

100
Q

Esomeprazole dose for active ulcer?

A

20-40mg daily/BID

101
Q

Lansoprazole dose for active ulcer?

A

15-30mg daily/BID

102
Q

Omeprazole dose for active ulcer?

A

20-40mg daily/BID

103
Q

Pantoprazole dose for active ulcer?

A

40mg daily/BID

104
Q

Rabeprazole dose for active ulcer?

A

20mg daily/BID

105
Q

Esomeprazole dose for PUD maintenance?

A

20-40mg daily

106
Q

Lansoprazole dose for PUD maintenance?

A

15-30mg daily

107
Q

Omeprazole dose for PUD maintenance?

A

20-40mg daily

108
Q

Pantoprazole dose for PUD maintenance?

A

40mg daily

109
Q

Rabeprazole dose for PUD maintenance?

A

20mg daily

110
Q

Sucralfate dosing?

A

1gm QID or 2g BID 2 hours before or 4 hours after other medications.

111
Q

Misoprostol dose for NSAID induced PUD prophylaxis?

A

200mcg PO BID-QID

112
Q

How long should H2RA or sucralfate therapy be continued for PUD?

A

6-8 weeks

113
Q

How long should PPI therapy for PUD be continued?

A

4 weeks

114
Q

Omeprazole dose for NSAID induced PUD prevention?

A

20mg daily

115
Q

Lansoprazole dose for NSAID induced PUD prevention?

A

15-30mg daily

116
Q

Rabeprazole dose for NSAID induced PUD prevention?

A

20mg daily

117
Q

Pantoprazole dose for NSAID induced PUD prevention?

A

40mg daily

118
Q

Esomeprazole dose for NSAID induced PUD prevention?

A

20-40mg daily

119
Q

How long should PPI/H2RA/sucralfate be continued for an NSAID induced ulcer if the NSAID was discontinued?

A

6-8 weeks

120
Q

How long should PPI be continued for an NSAID induced ulcer if the NSAID was NOT discontinued?

A

PPI for 8-12 weeks

Pharmacotherapy IV (4 decks)

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