Exam 1 Example Flashcards
Which one of the following is NOT an example of biotechnology application?
A. Agricultural Science
B. Pharmaceutical Science
C. Environment Science
D. Meteorological Science
E. Clinical Science
D. Meteorological Science
T/F: The following biotechnology milestone is correctly described?
Robert Edwards practiced the first successful in vitro fertilization
TRUE!
A good biomaterials have the following characteristics EXCEPT
A. not able to react with biological tissue
B. not exhibit cytotoxicity
C. can be flexible and rigid
D. can be synthetic or natural in composition
E. are organic in chemical structure
E. are organic in chemical structure
Which one of the following is NOT an example of a good biomaterial
A. titanium
B. ceramics
C. lead
D. PDMS
E. PMMA
c. lead
PDMS is commonly used biomaterial because
A. it can be molded easily by lithography
B. it has a good optical property
C. it can be made into soft or rigid products
D. it has low thermal conductivity
E. All of the above
E. All of the above
Young’s modulus is a measurement of
A. conductivity
B. pressure
C. rigidity
D. solubility
E. impedance
c. rigidity
Which of the following terms is NOT included in the Navier-Stokes equation?
A. inertia
B. pressure gradient
C. body force
D. velocity
E. viscosity
d. velocity
Fundamental principles of continuum mechanics obeys the following laws EXCEPT
A. conservation of molecules
B. conservation of mass
C. conservation of linear momentum
D. conservation of energy
E. conservation of angular momentum
a. conservation of molecules
Continuum mechanics can be best described by
A. discrete equations
B. study of material science in microscopic scale
C. study of behavior of solids and fluids
D. study of stress and strain
E. quantum mechanics
c. study of behavior of solids and fluids
Human heart
A. is the first organ developed during the embryonic stage
B. consists primarily of skeletal muscles
C. consists primarily of smooth muscles
D. is metabolically conservative (energy efficient)
E. can regenerate upon injury
a. is the first organ developed during the embryonic stage
Heart valves
A. can open in both directions
B. prevent blood flow from atria to ventricle
C. can only be replaced via open heart surgery
D. consists of pacemaker cells
E. none of the above
e. none of the above
ECMO
A. is a kidney dialysis machine
B. is a body temperature control device
C. is an external hepatic assist machine
D. supports oxygenation to heart and lung
E. supports enzymatic detoxification function
d. supports oxygenation to heart and lung
Which statement about LDL and HDL is correct
A. are glycoproteins
B. are nucleic acids
C. are carcinogens
D. are major causes of strokes
E. are diagnostic biomarkers
e. are diagnostic biomarkers
Which of the following is NOT an example of molecular diagnostic technique
A. Mass Spectrometry
B. Polymerase Chain Reaction
C. Magnetic Resonance Imaging
D. Chain Termination Sequencing
E. Sequencing by Synthesis
c. magnetic resonance imaging
Uric Acid
A. is biomarker for gout
B. is biomarker for kidney stones
C. is produced from the natural breakdown of body’s cells
D. is a by-product of the daily diet
E. all of the above
e. all of the above
The basic principles of PCR includes the following steps except
A. denaturing
B. annealing
C. extension
D. crystallization
E. none of the above
d. crystallization
Which description below about digital PCR is correct
A. it utilizes the SYBR dye
B. it is a relative quantification method
C. it does not require Taq polymerase enzyme
D. it works by dividing the starting mixture into small droplets
E. it requires a housekeeping gene as the control for quantification
d. it works by dividing the starting mixture into small droplets
Sanger sequencing is also known as the “chain termination” method because
A. it incorporates a dNTP terminator during the extension process
B. it is terminated after only a few hundred base-pairs during reaction
C. the sequences need to be read by running gel
D. it can only read a few hundred base-pairs of any continuous fragment
E. it is inspired by the movie “terminator”
a. it incorporated a dNTP terminator during the extension process
Next Generation Sequencing (NGS) methods
A. drastically reduce the cost of DNA sequencing
B. were awarded by the X-prize
C. were the techniques utilized to complete the Human Genome Project
D. involve the shotgun sequencing strategy
E. have become point-of-care diagnostic platforms
a. drastically reduce the cost of DNA sequencing
Which one of the followings is NOT an example of imaging diagnostic technology
A. Mass spectrometry
B. X-rays
C. Ultrasound
D. MRI
E. CT
a. mass spectrometry
Computed Tomography (CT) utilized which following principle
A. reflective sound waves
B. infrared waves
C. electromagnetic waves
D. ultraviolet waves
E. none of the above
c. electromagnetic waves
Which one of the following imaging techniques is suitable for monitoring dynamic (moving) tissues?
A. ultrasound
B. x-rays
C. CT
D. MRI
E. NMR
a. ultrasound
The purpose of a column buffer in Affinity Chromatography is to
A. equilibrate and wash
B. elute the sample
C. facilitate the ligand binding
D. preserve the samples
E. dissolve the mixtures
a. equilibrate and wash
An aneurysm is
A. a tumor mass
B. blood vessel plaque
C. a bulge in the blood vessel
D. thickening in the blood vessel walls
E. a localized tissue with insufficient blood supply
c. a bulge in the blood vessel
Atherosclerosis
A. can be promoted by LDL
B. can be treated by inserting a stent
C. can cause the blockage of blood vessel
D. can be alleviated by statin drugs
E. all of the above
e. all of the above
T/F: The following about the X-prizes is correct
Qualcomm X-Prize will be awarded for mobile diagnostic device
True!
The protection period for utility patents in the United States is
A. 20 years from the earliest filing date
B. 15 years from the issued date
C. 17 years from the end of provisional patent pending period
D. able to be extended after re-filing
E. automatically honored by the international law
a. 20 years from the earliest filing date
List 2 advantages and 2 disadvantages of biological and mechanical valves that are currently being utilized for valve replacement procedures
Describe the principle of PCR, and key feature of qPCR as well as Digital PCR in term of how they quantify/measure the gene expressions
Define Scalar
Define Vector
Define Stress
Define Strain
Define Inertia
Please list 3 examples of circulating biomarkers in the blood and describe the disease/clinical symptoms associated with them
- Blood Glucose: Used in diagnosis and treatment of carbohydrate metabolism such as Diabetes Mellitus and Neonatal Hypoglycemia
- Lipoproteins (HDL and LDL): Used in diagnosis for cadiovcascular diseases such as Atherosclerosis and Heart Attacks
- Uric Acid: Used in diagnosis of a type of arthritis known as gout
