Exam 1 drugs Flashcards

1
Q

What type of drug is amitriptyline?

A

Tricyclic antidepressant (TCA)

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2
Q

What type of drug is imipramine?

A

Tricyclic antidepressant (TCA)

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3
Q

What type of drug is escitalopram (Lexapro) ?

A

SSRI

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4
Q

What type of drug is fluoxetine (Prozac)?

A

SSRI

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5
Q

What type of drug is sertraline (Zoloft)?

A

SSRI

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6
Q

What type of drug is venlafaxine (Effexor ER)?

A

SNRI

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7
Q

What type of drug is duloxetine (Cymbalta)?

A

SNRI

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8
Q

What type of drug is phenelzine (Nardil)?

A

MAOI (monoamine oxidase inhibitor)

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9
Q

What type of drug is tranylcypromine (Parnate)?

A

MAOI

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10
Q

What type of drug is isocarboxazid (Marplan)?

A

MAOI

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11
Q

What type of drug is bupropion (Wellbutrin)?

A

Atypical antidepressant

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12
Q

List 2 examples of tricyclic antidepressants

A

Amitriptyline

Imipramine

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13
Q

What are tricyclic antidepressants commonly used for?

A
depression
anxiety
insomnia
fibromyalgia 
bipolar disorder
OCD
ADHD
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14
Q

What do tricyclic antidepressants do?

A

Block uptake of norepinephrine and serotonin

Increase concentration of serotonin and norepi in body, block acetylcholine, hence the anticholingeric effects

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15
Q

Nursing interventions of Tricyclic antidepressants (TCAs)

A
Take at bedtime
Take with food if GI upset
Change positions slowly
Chew sugarless gum if anticholinergic effects (dry mouth)
Increase fluid intake to 2-3L/day
High fiber foods (Avoid constipation)
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16
Q

List 3 examples of SSRIs

A
  1. escitalopram (Lexapro)
  2. fluoxetine (Prozac)
  3. sertraline (Zoloft)
17
Q

What do SSRIs do?

A

First line treatment for panic disorders and trauma

SSRIS block the reuptake of serotonin!! Increase concentration of serotonin in body!

18
Q

Common side effects of SSRIs:

A
Weight gain
Nausea/GI upset
BBW suicide
Sexual dysfunction
Insomnia
Serotonin syndrome
Hyponatremia (increased ASH, fluid retention, Na+ diluted)
19
Q

Nursing interventions SSRIs

A

Take in morning with food for GI upset
Report impotence/decreased libido
S/S hyponatremia
Do not stop taking abrupty. Education on slow onset (2-4 weeks)
Never mix St. John’s Wort, MAOIs with SSRIs

20
Q

Adverse drug reactions for TCAs:

A
Anticholinergic effects (too much= CNS depression)
HIGH** risk of drug overdose due to narrow therapeutic index:  can cause dysrythmias, confusion, seizures. 
BBW suicide
21
Q

Name 2 SNRIs

A

Venlafaxine (Effexor XR)
Duloxetine (Cymbalta)

Remember: vexed and Depressed

22
Q

What are SSRIs mainly prescribed for?

A

Depression, Panic, OCD

23
Q

What do SNRIs do?

A

Block uptake of norepi and serotonin

24
Q

What happens if you have high levels of Norepinephrine

A
Tachycardia
Fight or Flight
Urinary retention
Increased Blood glucose
decreased GI motility (constipation)
Anorexia (not focused on eating)
Increased BP
25
Q

What are SNRIs typically prescribed for?

A

Major depression, panic disorders, panic disorders, generalized anxiety disorders

26
Q

What are adverse drug reactions of SNRIs?

A
CNS excitement:  insomnia and nervousness
Nausea, GI upset, Heptatitis
Hyponatremia (ADH affected by serotonin)
Hypertension
Anorexia
BBW suicide!
27
Q

Client education for SNRIs

A
Take with food
Avoid taking close to bedtime
Monitor BP
Never stop abrupty!
Dont take other supplements without consulting Doc.
28
Q

List 2 examples of MAOIs

A

phenelzine (Nardil)

Tranylcypromine (Parnate)

29
Q

What do MAOIs do?

A

Increases amounts of serotonin, norepinephrine, and dopamine

30
Q

Adverse drug reactions of MAOIs

A
CNS excitement:  agitation, insomnia, mania
Orthostatic hypotension
GI upset
N/V
Liver/Kidney issues
31
Q

What conditions are MAOIs typically prescribed for?

A
Depression
Bulimia
Panic disorder
Social anxiety disorder
PTSD
32
Q

What should not be taken with MAOIs?

A

Foods containing tyramine
TCAs
Sympathomimetics
Sudafed, Coke, Adderall

Can cause hypertensive crisis!!!!!