Exam 1 Concepts Flashcards
delta notation of lipids starts from what end
carbonyl
omega notation of lipids starts from what end
methyl
omega notation of lipids starts from the same end as what other notation
N
eicosanoids - function
local hormones
examples of eicosanoids
prostaglandins, prostacyclins, thromboxanes, leukotrienes, lipoxins
phospholipid that functions as a bioeffector
phosphatidyl inositol
phospholipid that functions as a lung surfactant
dipalmitoyl lecithin
phospholipid that solubilizes cholesterol
phosphatidyl choline
names of 12C 14C 16C 18C 20C saturated FA
12C lauric 14C myristic 16C palmitic 18C stearic 20C arachidic
components of glycrophospholipids
phosphatidic acid
glycerol
important component of spingolipids
ceramide
structure of glycolipid
monosaccharide/oligosaccharide bound to ceramide
examples of glycolipids
cerebrosides, sulfatides, globosides, gangliosides
important component of ganglioside
N acetylneuramic acid
Tay-Sachs disease - pathophysiology
accumulation of gangliosides (GM2) causing mental retardation and loss of senses
phase transition temperature - define
temperature at which the plasma membrane undergoes the transition from ordered to disordered
effect of cholesterol on membrane above PTT
cholesterol keeps the membrane more solid (rigidity)
effect of cholesterol on membrane below PTT
cholesterol disrupts the arrangement of the hydrocarbons, allowing for more fluidity
agonist - define
substance that attaches to receptor and allows for mimicking of cell response
antagonist - define
substance that attaches to receptor and allows for inhibition of cell response
lipid soluble messengers - mechanism
direct diffusion through the plasma membrane –> attaches to nuclear membranes and DNA response elements