Exam 1-Biostatistics Flashcards
Continous
variables that can theoretically have values between points (decimal points)-i.e. peoples weight/height
discrete
no intermediate values (i.e. BP as hypotensive, normal, or hypertensive-OR number of students in a class)
Central tendency
most frequently used is mean, very sensitive to outliers (mean, median, and mode)
measures of dispersion
range (highest and lowest), interquartile range (75th percentile value minus 25th percentile value) and variance (spread data around the mean)
Dependent variable
outcome of interest
independent
risk factors or indicators of disease
Parametric vs non-parametric
parametric: make an assumption about the underlying distribution
non-parametric: do not make any assumptions about the distribution, therefore considered robust
Sample size determination-MED
minimum expected difference; smallest measured difference between comparison groups that the investigator would like the study to detect
Sample size determination-p-value
probability that the finding is by chance; if P is LESS than .05 study is statistically SIGNIFICANT
Sample size determination-Power
Ability to find a difference when there is a difference (80%) ,probability of rejecting the null hypothesis
Sample size determination-Confidence interval
a range that you think will contain the true population parameter that you are measuring, it can be a measure of statistical significance and precision
Sample size determination-Type 1 error
False discover, when we reject a true null hypothesis
Sample size determination-Type 2 error
when we fail to reject the null hypothesis that is false