Exam 1- Arthritis

Question 1

Difference between Primary and secondary OA

Answer 1

Primary- MC form, adults, no major trauma

Secondary- previous injury or deformity

Question 2

OA occurs where in men and women

Answer 2

Females- knees and hands

Males- hips

Question 3

What is chondromalacia

Answer 3

When matrix cracks and softens, exposes subchondral bone

Question 4

What is eburnation

Answer 4

Bony sclerosis and osteophytosis in OA

Question 5

What is a subchondral cyst

Answer 5

When fluid is in the bone due to OA

Possible joint mice= painful locking

Question 6

What is Heberden’s nodes?

Answer 6

Occurs in the hands due to OA at the DIP joints

Bouchard node occurs lover in the finger

Question 7

What Rheumatoid arthritis

Answer 7

Chronic autoimmune disease, CD4 +T cells, cytokines

+HLA-DRB1

Question 8

Tests for RA

Answer 8

Anti cyclic Citrullinated peptides 70% of cases smoking causes false positives

RF factor test IgM antibodies 80% accurate

Question 9

RA is most common where

Answer 9

Small joints hands/ wrist

30% of patients have Atlanto-axial instability

Pannus

Question 10

RA is more common in who?

Answer 10

Females 3-5x more likely ages 35-50

Ulnar deviation is symptom

Question 11

What is felty syndrome?

Answer 11

Combo of RA, splenomegaly, neutropenia

Presents as classic RA

Question 12

What’s neutropenia

Answer 12

Risk for recurrent infections

Question 13

What’s Caplin syndrome

Answer 13

Comb of RA, and Pneumoconiosis (coal)

Presents as RA

May mimic asthma, VERY RARE

Question 14

Juvenile Rheumatoid arthritis is

Answer 14

Less than 16 yrs old MC 1-6.

Oligoarticular- few joints
Polyarticular- many joints

Still’s disease- JRA+spiking fever, rash and pericarditis

MC at large joints knees and hips

Girls 2-3x more at risk

Question 15

Whats Scheuermann’s disease

Answer 15

Aka juvenile kyphosis of thoracolumbar spine

MC males, 13-16 familial

Question 16

Whats Seronegative Spondyloarthropathies

Answer 16

Autoimmune attach on spinal joints

Negative for RF
\+HLA-B27
PEAR
Psoriatic Arthritis
Enteropathic Arthritis
ANkylosing SPondylitis 
Reactive arthritis

Question 17

Reactive arthritis aka Reiters disease symptoms

Answer 17

Cant see
Cant pee
Cant climb a tree

Question 18

Ankylosing Spondylitis is

Answer 18

Inflammation and ankylosis of axial skelton

Onset- <40yrs old

Morning stiffness >30 mins unrelieved with lying, decreased chest expansion