Exam 1 Flashcards
An enzyme used in both glycolysis and gluconeogenesis is:
Phosphohexoisomerase
ATP can be hydrolyzed by several ways. In presence of COOH, which pairs of reactions the ATP provide MOST energy:
R-COOH + ATP + R-po2-Adenine+ PPi
How does Arsenate affect glycolysis:
It lead to the net production of no ATP
The main function of pentose phosphate pathway is to:
Supply pentose and NADPH
Which of the following are effects of Epinephrine: (K-type Q)
1) Activates glycogen phosphorylase
2) Blocks activation of glycogen synthase
Indicate the appropriate intermediate in the catabolism of lactose by completing the following sentences; Lactose is first broken into its component monomers one of these is glucose, the other is ___, can be catabolised through multi steps process to form ___ and intermediate of glycolysis.
Galactose, glucose-6-phosphate
The last step of glycolysis involve the conversion of phosphophenol pyruvate to pyruvate synthesized glucose, most organism accomplish the reversal of this reaction by employing a series of reactions different from the glycolytic reaction which bypass the glycolytic reaction.
2 Q’s are about this series of reaction:
1) Which of the following is true about this bypass:
2) Assuming that Lactate is not available how is NADH involve in the reversal reaction;
1) The reaction have a net requirement of 2 ATP equivalent per pyruvate
2) 1 mole is consumed in mitochondria and formed in the cytosol for each mole of pyruvate consumed
How many ATP equivalent and molecule of NADH are directly required for the synthesis of one molecule of glucose:
6 ATP, 2 NADH
Which of the following pairs of reaction is futile cycle:
Pyruvate + ATP + Posphophenolpyruvate + ADP Posphophenolpyruvate + H2O –> pyruvate + Pi
Which of the following is true about this pair of reactions : fructose 6 phosphate+ATP—fructose 1,6 phosphate +ADP
AMP promote reaction # 1 and inhibit reaction #2
Which of the following is true about the regulation of hexokinase:
Both 2 and 3:
2) in muscle tissue it is regulated by feed back inhibition
3) in liver tissue it is regulated primarily by the glucose concentration
There is resceprocal regulation of glycolytic and glucogenic reaction interconverting fructose 6 phosphate and fructose 1,6 biphosphate. What about this regulation is not correct:
Phosphofructokinase is endergonic
Pyruvate can either undergo a series of catabolic reactions yield energy or to be transformed into glucose (gluconeogenisis). The primary way of regulation how pyruvate is metabolized:
Acetyl Co promotes gluconeogensis and inhibits the catabolism of pyruvate
Which of the following will low blood glucose promote:
Activation of FBPase and inactivation of Pfk-1
The primary immediate product of glycogen break down is ——glucose 1-phosphate, the immediate substrate of glycogen is:
UDP glucose
