Exam 1 Flashcards
What are schedule 2 opioids?
Fentanyl, hydromirphone, methadone, morphine, oxymorons, & oxymorphone
Cyclobenzaprine
Centrally acting skeletal muscle relaxant
Depressed motor activity in the brain stem
Reputable inhibitor similar to TCAs
What to give a patient with EPS?
Benzotropine (cogentin)
Anticholinergic
Common skeletal muscle relaxants
Cuclobenzaprine
Baclofen
GABA agonists
Imidazolines
Skeletal muscle drug
-Nidine
Can benzodiazepines treat skeletal muscle hyperactivity?
Yes
Most important skeletal muscle relaxant?
Dantrolene
-interferes with calcium release from skeletal muscle
RISK FOR HEPATOTOXICITY
Neuromuscular blockers
Are depolarizing or nondepolarizing
Succinylcholine
Depolarizing blocker at NMJ
Prevents voluntary contraction
OD/ overrelaxation: causes difficulty swallowing and breathing
Risk for malignant hyperthermia
Dantrolene sodium (Dantrium)
Antispasmodic for head and neck
Interferes with release of calcium from skeletal muscle
Helps preoperatively < probability of malignant hyperthermia
Hepatoxicity
What is the preferred drug to treat partial and tonic clonic seizures?
Carbamazepine
Two drugs that treat all seizures
Valproic acid
Lamotrigine
Risperidone side effects
Increased prolactin levels
Atypical antipsychotics have what endings?
- pine (Clonzapine)
- done (Risperidone)
Buspirone
Sleep aid
Zolpidem (Ambien)
Good to help sleep through early morning hours
OD? - use flumazenil
Sympathominetics/catecholamines,noncatecholamines
Epi, NE, DA
Phenlyphrine- nasal decongestant only alpha 1 Receptors
Constricts blood vessels
Alpha Adrenergic Antagonists
Prazosin (minipress)
Antihypertensive
Phentolamine treats MAOI crisis
Mostly used for antihypertension
Propranolol
Beta1 and 2 blocker
Treats hypertension, HF
What is more addictive
Buprenorphine or
Pentazocine. Butophenol
Pentazocine and butophenol
Block Mu receptor
but use Kappa
Atypical Antipsychotics end in
- pine Clonzapine
- done
DA-serotonin System Stabilizers
Atypical Antipsychotic
Abilify
End in
-ZOLE
Cymbalta
Atypical antidepressant
SNRI
Treats neuropathic pain
Phenobarbitol can have what symptoms
Death lol
Agranulocytosis
Steven-Johnson’s syndrome
Adjuvant analgesics
Tregretol- treats trigrminal neuropathy
Valproic acid: treats migraines
Gabapentin: posttherpeutic neuroglia
Phenelzine (Nardil)
MAOI
Volatile liquids have what ending
-fluranes
Cause surgical level anesthesia
Excellent muscle relaxant
Don’t give with catecholamines
Lennox- GASTAUT
Bad seizures treated with valproic acid
Valproic acid is really bad for your
LIVER
Mechanisms of action for anti seizure
STIMULATE Cl- into cell
DELAY INFLUX NA AND CA
Taurine
< glutamate
What prevents malignant hyperthermia?
Dantrolene
Succinylcholine
DEPOLARIZING Neuromuscular blocker
Intubation necessary
How to treat lidocaine overdose?
Lipid Transfusion
Immunomodulators
Interferons
Glantiraner
Donepezil
> Ach
Only works if Neurons aren’t dead-> can’t use in later dementia
Cholinergic effects
Alzheimer drugs also < glutamate
Benztropine (cogentin)
Antiparkensins drug
Centrally acting Cholinergic receptor blocker
Anticholinergic side effects dry mouth, constipation, tachycardia
Efffects if antiparkinson’s drugs
Acute MI SHOCK NMS Hallucinations Angranulocytosis Depression EPS LIVER FAILURE
What bests relieves positive schizophrenic symptoms
Phenithiazines
-AZINE
