Exam 1 Flashcards
Mutations in ______ cells are more important
sex
they are passed on to next generations.
Point mutation-
change in one nucleotide
Substitution point mutations can be ________ (silent) or ________ (meaningful)
synonymous
non-synonymous
Silent mutation-
codon from this mutation specifies the same amino acid as the non-mutated codon. No protein change.
Codon-
triplet sequence of nucleotides that specifies a particular amino acid
Non-synonymous (meaningful) point mutation-
missense, different amino acid, different protein.
Large sections of chromosomal mutations-
deletion, duplication, inversion, insertion, translocation.
Gene position may or may not be important in its __________
expression
Trisomy 21 is due to _________. Leads to ___________
- nondisjunction, extra T21 chromosome
- Down Syndrome
Fusion of a chromosome might be a significant effect in __________
speciation
Estimated number of protein coding genes in humans
25,000
Gross generalization: mutation rate per generation is:
10^-5 or 10^-6
mutation rate (_______) is too low to be main force in evolution. Between _____% of us carry a genetic mutation compared to our parents. Although mutation is too low to be main force of evolution, it is the only source of ___________
- .025 to .25
- 5-44%
- new genes in a species.
Mutations increase genetic variability in a _________ and between __________
- population
- populations
Gene flow-
movement of alleles from one population to another due to mating between populations.
Gene flow inhibits speciation because ____________________
two populations blend their traits and they are now more similar and less likely to genetically diverge from each other.