Exam 1 Flashcards

1
Q

Mutations in ______ cells are more important

A

sex

they are passed on to next generations.

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2
Q

Point mutation-

A

change in one nucleotide

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3
Q

Substitution point mutations can be ________ (silent) or ________ (meaningful)

A

synonymous

non-synonymous

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4
Q

Silent mutation-

A

codon from this mutation specifies the same amino acid as the non-mutated codon. No protein change.

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5
Q

Codon-

A

triplet sequence of nucleotides that specifies a particular amino acid

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6
Q

Non-synonymous (meaningful) point mutation-

A

missense, different amino acid, different protein.

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7
Q

Large sections of chromosomal mutations-

A

deletion, duplication, inversion, insertion, translocation.

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8
Q

Gene position may or may not be important in its __________

A

expression

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9
Q

Trisomy 21 is due to _________. Leads to ___________

A
  • nondisjunction, extra T21 chromosome

- Down Syndrome

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10
Q

Fusion of a chromosome might be a significant effect in __________

A

speciation

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11
Q

Estimated number of protein coding genes in humans

A

25,000

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12
Q

Gross generalization: mutation rate per generation is:

A

10^-5 or 10^-6

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13
Q

mutation rate (_______) is too low to be main force in evolution. Between _____% of us carry a genetic mutation compared to our parents. Although mutation is too low to be main force of evolution, it is the only source of ___________

A
  • .025 to .25
  • 5-44%
  • new genes in a species.
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14
Q

Mutations increase genetic variability in a _________ and between __________

A
  • population

- populations

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15
Q

Gene flow-

A

movement of alleles from one population to another due to mating between populations.

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16
Q

Gene flow inhibits speciation because ____________________

A

two populations blend their traits and they are now more similar and less likely to genetically diverge from each other.

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17
Q

Genetic drift-

A

random change in allele frequencies

18
Q

The smaller the population, the more chance of significant ________

A

mutations

19
Q

Two inferences we can make about genetic drift:

A
  1. All populations evolve every generation by genetic drift

2. magnitude of evolution by genetic drift is greater in a smaller population than a larger population

20
Q

The ultimate result of genetic drift is ___________, and all other alleles of the gene have been _______________

A
  • fixation of an allele

- eliminated from the population

21
Q

Bottleneck and Founder effects-

A

reduction in genetic variability by chance due to reduction in population size (bottleneck) or establishment of a new, founder population.

22
Q

Natural selection-

A

differences among individuals in reproductive success

23
Q

The unit of natural selection is _________; the unit of evolution is ___________

A
  • the individual organism

- the population (or species)

24
Q
  • Adaptation- result of _________

- Individuals are subject to natural selection, whereas populations (or species) _______

A
  • natural selection

- adapt

25
Q

-Adaptation occurs only if differences among individuals in reproductive success have ____________

A

some inheritable basis.

26
Q

Fundamental Theory of Natural Selection-

A

opportunity for natural selection is directly related to genetic variability in a population (or species)

27
Q

There must be ____________________ for there to be natural selection.

A

genetic differences among individuals in a population (or species), and correspondingly phenotypic differences,

28
Q

Natural selection “acts” directly on __________, and indirectly on ____________

A
  • phenotypic variability

- genetic variability

29
Q

Natural selection –

A

differential reproductive success among individuals in a population (or species).

30
Q

Three “types” of natural selection

A

stabilizing selection, directional selection, and diversifying selection

31
Q

Stabilizing selection –

-Result is to reduce variability in the _________, but no change in _______

A
  • selection against individuals at both ends of the phenotypic distribution curve.
  • distribution curve
  • the mean value
32
Q

Directional selection – ____________. Result is a change in the _____________.

A
  • selection for individuals at one end of the phenotypic distribution curve.
  • mean value of the distribution
33
Q

Diversifying selection – ____________________. Result is ______________.

A
  • selection against individuals in the intermediate range of the phenotypic distribution curve, and selection for individuals at the ends of the distribution curve
  • two modalities in phenotypic distribution
34
Q

Units of natural selection:

A
  • gene
  • individual organism
  • group (i.e., population)
  • species
35
Q

For a “unit” to be subject to natural selection, the trait _____________ and there must be __________.

A
  • must be inheritable

- variance within that unit

36
Q

Units of natural selection

  1. Gene-
  2. Individual organism-
  3. Group (i.e., population)-
  4. Species-
A
  • meiotic drive: allele is transmitted to offspring at a rate higher than 50%
  • classic Darwinian theory
  • individuals in the group sacrifice their reproductive success to ensure group survival
  • Species differ among themselves in likelihood of speciation; lineages with high speciation rates persist, whereas those with low speciation rates go extinct
37
Q

Kin selection
1.
2.
also called 3.

A
  1. just more natural selection at level of individual organism
  2. Individual may reduce her/his reproductive success by aiding the reproductive success of her/his “kin”
  3. altruism
38
Q

Kin selection is simply part of an organism’s ___________ and can be considered to be natural selection among individual organisms.

A

inclusive fitness

39
Q

Inclusive fitness:

A

an individual’s genetic contribution to the next generation is based on both one’s own reproduction and by reproduction of one’s relatives.

40
Q

5 concepts of a species:

A
  • Biological species
  • Evolutionary species
  • Morphological species
  • Ecological species
  • Recognition species
41
Q

Biological Species:

A

Group(s) of actually or potentially interbreeding organisms that are reproductively isolated from other such groups.