Exam 1 Flashcards

1
Q

Benzodiazepines uses

A

Insomnia
Anxiety
Status epilepticus seizes
Muscle spasms

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2
Q

Benzodiazepines side effects

A
Drowsiness
Dizziness 
Confusion
Anxiety
Toxicity 
Withdrawal
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3
Q

Non-Benzodiazepines prototype

A

Zolpidem (Ambien)

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4
Q

Non-Benzodiazepines uses

A

Short term treatment of Insomnia

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5
Q

Non-Benzodiazepines side effects

A

Dizziness, Drowsiness, anxiety, confusion, diplopia (double vision), headache, amnesia

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6
Q

Non-Benzodiazepines instructions

A

Take before bed

Take on an empty stomach

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7
Q

Non-Benzodiazepines contraindications

A

Suicidal ideation

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8
Q

Benzodiazepines instructions

A

Take before bed

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9
Q

Benzodiazepines contraindications

A

Glaucoma

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10
Q

Centrally Acting Relaxants prototype

A

Baclofen (Lioresal)

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11
Q

Centrally Acting Relaxants uses

A
Relieve muscle spasms due to:
Spinal cord injury
Cerebral Palsy
Multiple Sclerosis 
Musculoskeletal injury
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12
Q

Centrally Acting Relaxants side effects

A

Drowsiness and dizziness early in treatment, constipation, nausea, withdrawal

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13
Q

Centrally Acting Relaxants instructions

A

Take with food or milk

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14
Q

Centrally Acting Relaxants interactions

A

Cyclobenzaprine (Flexeril) and MAOIs cause hypertensive crisis

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15
Q

Benzodiazepines prototype

A

Diazepam (Valium)

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16
Q

Peripherally Acting Muscle Relaxants prototype

A

Dantrolene (Dantrium)

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17
Q

Peripherally Acting Muscle Relaxants uses

A
Relax skeletal muscle spasms related to:
Cerebrovascular accident
Spinal cord injury
Multiple sclerosis
Cerebral Palsy
Prevent and treat malignant hyperthermia
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18
Q

Peripherally Acting Muscle Relaxants side/adverse effects

A

Muscle weakness, drowsiness, dizziness, diarrhea, liver toxicity

19
Q

Peripherally Acting Muscle Relaxants instructions

A

Avoid driving and activities that require mental alertness, CNS depressants (alcohol)

20
Q

Peripherally Acting Muscle Relaxants contraindications

A

Liver disease

21
Q

Peripherally Acting Muscle Relaxants interactions

A

CNS depressants such as alcohol increase the risk of severe sedation, calcium channel blockers increase risk of severe cardiac dysrhythmias,
Estrogen use

22
Q

Hydantoins prototype

A

Phenytoin (Dilantin)

23
Q

Hydantoins uses

A

Tonic-Clonic seizures

Partial seizures

24
Q

Hydantoins side/adverse effects

A

Mild drowsiness and other CNS effects,
Gingival hyperplasia,
Skin Rash,
Withdrawal symptoms

25
Q

Hydantoins instructions

A
  • Do not drive or perform other hazardous activities if experiencing CNS depressant effects.
  • Brush teeth with soft-bristled toothbrush, massage guns, and floss
  • Do not stop taking phenytoin abruptly
26
Q

Hydantoins contraindications

A
  • Bradycardia or heart block
  • Seizures caused by low blood sugar
  • Previous allergy
27
Q

Hydantoins interactions

A

IV Phenytoin is Incompatible in solution with other drugs and dextrose solution

Alcohol
CNS depressants

28
Q

Valproic Acid prototype

A

Valproic Acid (Depakote)

29
Q

Valproic Acid uses

A
  • all seizure types
  • maina associated with bipolar disorder
  • migraine headache (prevention)
30
Q

Valproic Acid side/adverse effects

A
  • Gastrointestinal upset
  • Bruising, bleeding, prolonged bleeding, decreased platelets
  • skin rash
  • liver toxicity
  • hyperammonemia
31
Q

Iminostilbenes prototype

A

Carbamazepine (Tegretol)

32
Q

Iminostilbenes uses

A
  • Partial seizures
  • Tonic-Clonic seizures
  • Bipolar disorder
  • Trigeminal neuralgia
33
Q

Iminostilbenes side effects

A
  • visual disturbances (headache, ataxia, nystagmus, blurred vision)
  • decreased excretion of water (fluid retention)
  • skin rash
  • bone marrow suppression
34
Q

Iminostilbenes instructions

A
  • begin with a low dose and gradually increase
  • take at bedtime
  • no driving
  • use sunscreen/ limit sun exposure
35
Q

Iminostilbenes contraindications

A

Hematologic disorders

Heart failure

36
Q

Iminostilbenes interactions

A

Grapefruit juice

Effectiveness of oral contraceptions

37
Q

Valproic Acid contraindications

A

Liver disorder
Thrombocytopenia
Hyperammonemia

38
Q

Valproic Acid instructions

A

Monitor bleeding time, and platelet count. Monitor blood ammonia levels.
Ensure patient takes lowest effective dose

39
Q

Valproic acid interactions

A

Topiramate (Topamax) increases risk for hyperammonemia

40
Q

Drugs for seizures

A
  • Benzodiazepines (Diazepam)
  • Hydantoins (Phenytoin)
  • Iminostilbenes (Carbamazepine)
  • Valproic Acid (valproic acid)
41
Q

Drugs for sleep disorders

A
  • Benzodiazepines (Diazepam )

- Non-Benzodiazepines (Zolpidem)

42
Q

Drugs for muscle spasms

A
  • Centrally acting muscle relaxants (Baclofen)

- Peripherally acting muscle relaxants ( Dantrolene)

43
Q

Drugs for anesthesia

A
  • Local Anesthesia (Lidocaine)
  • General Anesthesia/ Barbiturates (Sodium thiopental)
  • General anesthesia/ Benzodiazepines (Midazolam)
  • General anesthesia/ Opioids (Fentanyl)