Exam 1 Flashcards

1
Q

t(14;18)

A

Follicular lymphoma

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2
Q

+BCL2

A

Follicular lymphoma

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3
Q

MYD88

A

Lymphoplasmacytic Lymphoma

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4
Q

Two reasons for general leukocytosis

A

1) Reactive

2) Neoplastic

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5
Q

Tingible body macrophages

A

Follicular hyperplasia

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6
Q

Cytokine storm with shock like syndrome

A

HLH

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7
Q

t(12;21)

A

BALL

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8
Q

Smudge cells

A

CLL

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9
Q

Richter syndrome

A

CLL

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10
Q

Proliferation syndromes

A

CLL

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11
Q

ETV6/RUNX1

A

BALL

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12
Q

NOTCH1

A

TALL

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13
Q

+TdT

A

ALL

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14
Q

t(14;18)

A

Follicular lymphoma

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15
Q

Most common indolent NHL

A

Follicular lymphoma

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16
Q

BCL2+

A

Follicular lymphoma

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17
Q

Hepatization of spleen

A

Follicular lymphoma

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18
Q

Most common NHL

A

DLBCL

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19
Q

BCL6+

A

DLBCL

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20
Q

MYC gene

A

Burkitt lymphoma

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21
Q

Mandible/Abd viscera

A

African Endemic Burkitt lymphoma

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22
Q

Ileocecum/Peritoneum

A

Sporadic/American Burkitt Lymphoma

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23
Q

Starry sky pattern

A

Burkitt lymphoma

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24
Q

Royal blue cytoplasm

A

Burkitt lymphoma

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25
Rouleaux formation
Multiple myeloma
26
Syndecan-1
Multiple myeloma
27
Cyclin D1
Multiple myeloma | Mantle cell lymphoma
28
Serum M protein >3 gm ASx
Smoldering myeloma
29
Serum M protein < 3gm
MGUS
30
Serum M protein >3 gm Sx
Multiple myeloma
31
MYD88
Lymphoplasmacytic Lymphoma
32
Waldenstrom macroglobulinemia
Lymphoplasmacytic lymphoma
33
Hyper igM
Lymphoplasmacytic Lymphoma
34
t(11;14)
Mantle cell lymphoma
35
Polyp lesions in gut
Mantle cell lymphoma
36
BCL10
Marginal zone lymphoma
37
MALT1
Marginal zone lymphoma
38
Regress if inciting Ag is eradicated
Marginal zone lymphoma
39
Chronic inflammatory
Marginal zone lymphoma
40
BRAF
Hairy Cell Leukemia/ LHL Pulmonary
41
Dry tap
Hairy Cell Leukemia
42
CD11c
Hairy Cell Leukemia
43
Annexin A1
Hairy Cell Leukemia
44
Atypical mycobacterium
Hairy Cell Leukemia
45
Hallmark cells
Anaplastic Large Cell Lymphoma ALK Positive
46
HTLV1
Adult T Cell Leukemia lymphoma
47
Cerebriform nuclei
Mycosis fungoides, sezary syndrome
48
STAT3
Large granular lymphocytic leukemia
49
Felty syndrome
Large granular lymphocytic leukemia
50
Destructive nasopharyngeal mass
Extranodal NK T cell lymphoma
51
Deposition of collagen in bands
Nodular scerosis HL
52
t(15;17)
Acute Promyelocytic leukemia
53
Presence of at least 20% myeloid blasts
AML
54
Auer rods
AML
55
RNA splicing factors
MDS
56
Ring sideroblasts
MDS
57
JAK2 gene
MPD
58
Low EPO
PV
59
Low leukocyte alkaline phosphatase
CML
60
Imatinib
CML Tx
61
Obliterative marrow fibrosis caused by non-neoplastic fibroblasts
Primary myelofibrosis
62
Tear drop RBCs (Dacrocytes)
Primary myelofibrosis
63
Letterer-Siwe Disease
Multifocal multisystem LCH
64
Diabetes insipidus
Multifocal unisystem LCH
65
Birbeck granulues
Langerhans Cell Histiocytosis
66
What is unregulated in Mantle Cell?
NF-KB
67
BCL6/CD20
HL Lymphocyte Predominant