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HEME II > Exam 1 > Flashcards

Exam 1 Flashcards

1
Q

t(14;18)

A

Follicular lymphoma

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2
Q

+BCL2

A

Follicular lymphoma

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3
Q

MYD88

A

Lymphoplasmacytic Lymphoma

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4
Q

Two reasons for general leukocytosis

A

1) Reactive

2) Neoplastic

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5
Q

Tingible body macrophages

A

Follicular hyperplasia

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6
Q

Cytokine storm with shock like syndrome

A

HLH

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7
Q

t(12;21)

A

BALL

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8
Q

Smudge cells

A

CLL

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9
Q

Richter syndrome

A

CLL

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10
Q

Proliferation syndromes

A

CLL

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11
Q

ETV6/RUNX1

A

BALL

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12
Q

NOTCH1

A

TALL

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13
Q

+TdT

A

ALL

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14
Q

t(14;18)

A

Follicular lymphoma

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15
Q

Most common indolent NHL

A

Follicular lymphoma

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16
Q

BCL2+

A

Follicular lymphoma

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17
Q

Hepatization of spleen

A

Follicular lymphoma

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18
Q

Most common NHL

A

DLBCL

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19
Q

BCL6+

A

DLBCL

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20
Q

MYC gene

A

Burkitt lymphoma

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21
Q

Mandible/Abd viscera

A

African Endemic Burkitt lymphoma

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22
Q

Ileocecum/Peritoneum

A

Sporadic/American Burkitt Lymphoma

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23
Q

Starry sky pattern

A

Burkitt lymphoma

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24
Q

Royal blue cytoplasm

A

Burkitt lymphoma

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25
Q

Rouleaux formation

A

Multiple myeloma

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26
Q

Syndecan-1

A

Multiple myeloma

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27
Q

Cyclin D1

A

Multiple myeloma

Mantle cell lymphoma

28
Q

Serum M protein >3 gm ASx

A

Smoldering myeloma

29
Q

Serum M protein < 3gm

A

MGUS

30
Q

Serum M protein >3 gm Sx

A

Multiple myeloma

31
Q

MYD88

A

Lymphoplasmacytic Lymphoma

32
Q

Waldenstrom macroglobulinemia

A

Lymphoplasmacytic lymphoma

33
Q

Hyper igM

A

Lymphoplasmacytic Lymphoma

34
Q

t(11;14)

A

Mantle cell lymphoma

35
Q

Polyp lesions in gut

A

Mantle cell lymphoma

36
Q

BCL10

A

Marginal zone lymphoma

37
Q

MALT1

A

Marginal zone lymphoma

38
Q

Regress if inciting Ag is eradicated

A

Marginal zone lymphoma

39
Q

Chronic inflammatory

A

Marginal zone lymphoma

40
Q

BRAF

A

Hairy Cell Leukemia/ LHL Pulmonary

41
Q

Dry tap

A

Hairy Cell Leukemia

42
Q

CD11c

A

Hairy Cell Leukemia

43
Q

Annexin A1

A

Hairy Cell Leukemia

44
Q

Atypical mycobacterium

A

Hairy Cell Leukemia

45
Q

Hallmark cells

A

Anaplastic Large Cell Lymphoma ALK Positive

46
Q

HTLV1

A

Adult T Cell Leukemia lymphoma

47
Q

Cerebriform nuclei

A

Mycosis fungoides, sezary syndrome

48
Q

STAT3

A

Large granular lymphocytic leukemia

49
Q

Felty syndrome

A

Large granular lymphocytic leukemia

50
Q

Destructive nasopharyngeal mass

A

Extranodal NK T cell lymphoma

51
Q

Deposition of collagen in bands

A

Nodular scerosis HL

52
Q

t(15;17)

A

Acute Promyelocytic leukemia

53
Q

Presence of at least 20% myeloid blasts

A

AML

54
Q

Auer rods

A

AML

55
Q

RNA splicing factors

A

MDS

56
Q

Ring sideroblasts

A

MDS

57
Q

JAK2 gene

A

MPD

58
Q

Low EPO

A

PV

59
Q

Low leukocyte alkaline phosphatase

A

CML

60
Q

Imatinib

A

CML Tx

61
Q

Obliterative marrow fibrosis caused by non-neoplastic fibroblasts

A

Primary myelofibrosis

62
Q

Tear drop RBCs (Dacrocytes)

A

Primary myelofibrosis

63
Q

Letterer-Siwe Disease

A

Multifocal multisystem LCH

64
Q

Diabetes insipidus

A

Multifocal unisystem LCH

65
Q

Birbeck granulues

A

Langerhans Cell Histiocytosis

66
Q

What is unregulated in Mantle Cell?

A

NF-KB

67
Q

BCL6/CD20

A

HL Lymphocyte Predominant

HEME II (2 decks)

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