Exam 1 Flashcards

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0
Q

Keratin sulfate

A

Cornea, bone, cartilage

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1
Q

Chondroitin sulfate

A

Cartilage, bone, heart valves, tendons, ligaments. Increase with compression

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2
Q

Dermatan sulfate

A

Skin, blood vessels, tendons, ligaments. Increase with tensile strength

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3
Q

Fibronectin

A

Interacts with cell surface receptors and gags. Blood clotting components, denatured collagen, cytoskeleton

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4
Q

Laminin

A

In basement membrane. Bonds type 4 collagen, HS, and integrin

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5
Q

Chondronectin

A

Found in cartilage. Attaches chondrocytes to type 2 collagen.

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6
Q

Main PG of ligaments

A

Dermatan sulfate

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7
Q

Collagen content of ligament

A

Type 1, varying amounts of 3,4,5 and elastin

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8
Q

Collagen types in tendons

A

Primarily type 1. Type 3 in tendon sheaths. Types 4 and 5 in basal lamina of fibroblasts

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9
Q

Endotendon

A

Encloses fibers to form fascicles. Contains mostly type 3 collagen fibrils

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10
Q

Tensosynovium

A

Peritendon becomes a synovium filled sheath in tendons that are subjected to high levels of friction

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11
Q

Collagen types in cartilage

A

Type 2. Type 9 to interact with proteogylcans. Type 11 regulates fibril size

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12
Q

Main PG associated with cartilage

A

KS and CS in aggrecan

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13
Q

Collagen type in fibrocartilage

A

Type 1. Where little motion occurs

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14
Q

Main type of collagen in bone

A

Type 1

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15
Q

What does SAID stand for

A

Specific adaptation to imposed demand

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16
Q

Collagen type of fibroblasts

A

Type 1

17
Q

Collagen type of chondroblasts

A

Type 2

18
Q

Collagen type of osteoblasts

A

Type 1 and hydroxyapatite

19
Q

Role of mast cells

A

Inflammatory mediators

20
Q

Mesenchymal cells

A

Undifferentiated cells found in embryos. Can differentiate into different CT

21
Q

Aggregan

A

Chains of KS and CS attached to hyalouranon. Creates osmotic swelling pressure in cartilage by attracting water

22
Q

Fibrous synarthroses

A

Suture, gomphoses, and syndesmoses

23
Q

Cartilaginous synarthroses

A

Symphysis and synchondroses

24
Q

Hyalouranon

A

Non sulfated. Independent GAG. Maintains strength of cartilage.

25
Q

Ruffini

A

Stretch (extremes of extension)

26
Q

Pacini

A

Compression or changes in hydrostatic pressure

27
Q

Golgi

A

Pressure and forceful joint motion

28
Q

Unmyelinated

A

Noxious and non noxious mechanical or bio mechanical stress

29
Q

Sutures

A

Connected by dense fibrous tissue. Edges overlap. Found in skull

30
Q

Synostosis

A

Fusion of suture

31
Q

Gomphoses

A

Situated like a peg in a hole. Tooth in mandible

32
Q

Syndesmoses

A

Joined directly by ligament or membrane. Shaft of tibia and fibula.

33
Q

Symphysis

A

Joined by fibrocartilage in form of disc or plate. Covered with lamina or hyaline cartilage. Intervertebral discs. Pubic symphysis

34
Q

Synchondrosis

A

Connected by hyaline cartilage. Forms between ossifying centers in bone. Found in skull and areas of bone growth.

35
Q

Stratum fibrosum

A

Outer layer of joint capsule. Type 1 collagen. Poorly vascularized, richly innervated.

36
Q

Stratum synovium and two layers

A

Inner layer of joint capsule
Highly vascularized poorly innervated
Intima is composed of synoviocytes
Subsynovial tissue is outside Intima. Highly vascularized. Contains most of the joint receptors.

37
Q

Uniaxial joints

A

Hinge

Pivot

38
Q

Biaxial joints

A

Condyloid

Saddle

39
Q

Triaxial joints

A

Plane

Ball and socket