Exam 1 Flashcards

0
Q

Keratin sulfate

A

Cornea, bone, cartilage

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1
Q

Chondroitin sulfate

A

Cartilage, bone, heart valves, tendons, ligaments. Increase with compression

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2
Q

Dermatan sulfate

A

Skin, blood vessels, tendons, ligaments. Increase with tensile strength

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3
Q

Fibronectin

A

Interacts with cell surface receptors and gags. Blood clotting components, denatured collagen, cytoskeleton

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4
Q

Laminin

A

In basement membrane. Bonds type 4 collagen, HS, and integrin

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5
Q

Chondronectin

A

Found in cartilage. Attaches chondrocytes to type 2 collagen.

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6
Q

Main PG of ligaments

A

Dermatan sulfate

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7
Q

Collagen content of ligament

A

Type 1, varying amounts of 3,4,5 and elastin

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8
Q

Collagen types in tendons

A

Primarily type 1. Type 3 in tendon sheaths. Types 4 and 5 in basal lamina of fibroblasts

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9
Q

Endotendon

A

Encloses fibers to form fascicles. Contains mostly type 3 collagen fibrils

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10
Q

Tensosynovium

A

Peritendon becomes a synovium filled sheath in tendons that are subjected to high levels of friction

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11
Q

Collagen types in cartilage

A

Type 2. Type 9 to interact with proteogylcans. Type 11 regulates fibril size

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12
Q

Main PG associated with cartilage

A

KS and CS in aggrecan

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13
Q

Collagen type in fibrocartilage

A

Type 1. Where little motion occurs

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14
Q

Main type of collagen in bone

A

Type 1

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15
Q

What does SAID stand for

A

Specific adaptation to imposed demand

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16
Q

Collagen type of fibroblasts

17
Q

Collagen type of chondroblasts

18
Q

Collagen type of osteoblasts

A

Type 1 and hydroxyapatite

19
Q

Role of mast cells

A

Inflammatory mediators

20
Q

Mesenchymal cells

A

Undifferentiated cells found in embryos. Can differentiate into different CT

21
Q

Aggregan

A

Chains of KS and CS attached to hyalouranon. Creates osmotic swelling pressure in cartilage by attracting water

22
Q

Fibrous synarthroses

A

Suture, gomphoses, and syndesmoses

23
Q

Cartilaginous synarthroses

A

Symphysis and synchondroses

24
Hyalouranon
Non sulfated. Independent GAG. Maintains strength of cartilage.
25
Ruffini
Stretch (extremes of extension)
26
Pacini
Compression or changes in hydrostatic pressure
27
Golgi
Pressure and forceful joint motion
28
Unmyelinated
Noxious and non noxious mechanical or bio mechanical stress
29
Sutures
Connected by dense fibrous tissue. Edges overlap. Found in skull
30
Synostosis
Fusion of suture
31
Gomphoses
Situated like a peg in a hole. Tooth in mandible
32
Syndesmoses
Joined directly by ligament or membrane. Shaft of tibia and fibula.
33
Symphysis
Joined by fibrocartilage in form of disc or plate. Covered with lamina or hyaline cartilage. Intervertebral discs. Pubic symphysis
34
Synchondrosis
Connected by hyaline cartilage. Forms between ossifying centers in bone. Found in skull and areas of bone growth.
35
Stratum fibrosum
Outer layer of joint capsule. Type 1 collagen. Poorly vascularized, richly innervated.
36
Stratum synovium and two layers
Inner layer of joint capsule Highly vascularized poorly innervated Intima is composed of synoviocytes Subsynovial tissue is outside Intima. Highly vascularized. Contains most of the joint receptors.
37
Uniaxial joints
Hinge | Pivot
38
Biaxial joints
Condyloid | Saddle
39
Triaxial joints
Plane | Ball and socket