Exam 1 Flashcards
Is the nucleus of origin motor or sensory in function
Motor
Is the nuclei of termination motor or sensory in function
Sensory
How many pairs of spinal nerves are there?
31
What does the dura become after leaving CNS while surrounding nerves
Epineurium
Are DRG’s associated with the anterior or posterior horn
Posterior
What neurotransmitter do the somatic nerve fibers release at target? Is there is a ganglion before on the way to target?
ACH
No, straight from CNS to target
Glands, Cardiac tissue, and smooth muscle are all examples of what part of the nervous system
Autonomic (Visceral)
What vertebral levels would you find autonomic sympathetic fibers? Are there ganglion in the pathway? If so, where are they located?
T1-L2
Yes, they are right outside the CNS (sympathetic trunk)
What neurotransmitters are released in the autonomic sympathetic nervous system
ACH at ganglion, Norepinephrine at target
True or false; autonomic sacral splanchnic fibers are parasympathetic
False, they are sympathetic (“S” in Sacral for Sympathetic)
All of the sympathetic splanchnics are: Greater, Lesser, Least, and Sacral
True or false; autonomic pelvic splanchnic fibers are parasympathetic
True, the “P” in pelvic for parasympathetic
Where do autonomic parasympathetic fibers originate from? Are there ganglion in the pathway? If so, where are they located
From brain or S2-S4 (Pelvic splanchnics)
Yes, and close to the target organ
What neurotransmitters are released in the autonomic parasympathetic system
ACH at ganglion and ACH at target
True or false; the parasympathetic system supplies essentially the same organs as the sympathetic with fewer blood vessels
True
True or False; lower motor neurons are primarily in the anterior horn
True
Where do the typical first order neuron somatic sensory fibers lie in?
Dorsal root spinal ganglion
Where do the typical second order neurons in the somatic sensory pathway travel and communicate with?
they decussate and go to thalamus
Where do third order neurons relay information in the somatic sensory pathway
Cerebral cortex
True or false, a thin layer or mucus covers the olfactory epithelium
True
What kind of cell are olfactory neurons?
Bipolar
How many central processes (axons) are there typically in olfactory pathway? Where do they convey information?
10 to 20
Olfactory bulbs
True or false; olfactory neurons are myelinated?
False, they are covered in schwann cells
Where is the first place olfactory neurons synapse?
After they pass through the cribiform plate they synapse on dendrites of mitral cells
True or false; at olfactory neurons first synapse, synaptic glomeruli are formed
True
What are mitral cells associated with?
Olfaction
True or false; mitral cells send information posterior via the olfactory tract and splitting into the medial and lateral olfactory striae
True
Where do medial stria fibers run in olfactory pathway?
They cross midline via anterior commissure and travel to opposite olfactory bulb
True or false; Lateral stria fibers carry information to primary olfactory cortex?
True
The periamygdaloid and prepiroform area, including the uncus and broad man areas 34 and 28 are all part of what?
Primary olfactory cortex
True or false; in the olfactory pathway, there is a synapse in the thalamus
False
True or false; all sensory information in the cranial nerves travels through the thalamus except olfaction
True
What is anosmia
Loss of olfaction
Why is the vomernasal nerve important in animals? Is it important in humans?
It allows animals to track
No, it isn’t developed well in humans
True or false; CN 2 is afferent only?
True
True or false; the eyeball is composed of 4 layers
False, it is composed of 3
What are the 2 layers of the outermost layer of the eyeball called?
Sclera (white) and Cornea (clear)
Name the 3 parts of the middle layer of the eyeball
Ciliary body
Iris
Choroid
How many layers are there in the innermost layer of the eyeball?
10
How many types of cones are there in the eye?
3; red, green, and blue
Where do we have the clearest vision? What is more concentrated here?
Fovea centralis- more cones
True or False; there are no rods in fovea
True
The periphery of the retina is almost completely composed of what kind of cell?
Rods
When depolarized who do photoreceptors relay information to? Where is this?
Bipolar cells in outer plexiform layer
Where are bipolar cells in the CN 2 pathway typically found?
inner nuclear layer
In the CN 2 pathway, bipolar cells relay information to ganglion cells, the synapse occurs in what layer?
Inner plexiform layer
Where do the optic nerves enter the skull? What do they unite to form?
through optic canal
optic chiasma
Are optic nerve axons myelinated
Yes
What cells for myelin?
Olegodendrocytes
What two muscles are influenced by the tectospinal tract
SCM and Trapezius
True or false; the optic tract travels around the cerebral peduncles and fibers synapse on one of 3 nuclei or termination
True
What the nuclei or termination for most fibers in the optic tract?
Lateral geniculate body
Optic tract fibers synapsing on the superior colliculus tells you what muscles will be influenced?
SCM and Trapezius because part of the tectospinal tract
What is the third nuclei or termination for the optic tract? What kind of reflexes are they associated with
Pretectal nucleus of the midbrain
Fibers deal with light reflexes
True or false; you need both eyes functioning properly for good depth perception
True
True or False; CN 3 is only afferent in nature
False, it is only Efferent
CN 3 is a motor nerve supplying how many extra ocular muscles
5, CN 3 supplies all extra ocular muscles except superior oblique and lateral rectus
True or false; CN 3 carries both somatic and parasympathetic fibers
True
True or false; CN 3 nuclei are somatic nuclei of origin located in the periaqueductal gray of the midbrain
True
What part of the cerebral cortex sends axons to the oculomotor nuclei
Brodmann area 8
True or False; axons from the oculomotor nucleus do not travel through the red nucleus
False, they do
Where do nerve fibers exit the skull in the oculomotor pathway
Superior orbital fissure
True or False, once nerve fibers in the oculomotor pathway exit the SOF they split into a superior and inferior rami
True
True or false once the motor fibers of the oculomotor nerve exit the CNS they will be covered with myelin
True
What muscles are supplied by the superior ramus of the oculomotor nerve
Superior rectus and Levator palpabrae superiorus
What muscles are supplied by the inferior ramus of the oculomotor nerve
Inferior rectus (central branch) Medial rectus (medial branch) Inferior Oblique (lateral branch)
The accessory oculomotor nucleus (Edinger Westphal) contains what kind of neurons? Where do they synapse?
Preganglionic parasympathetic (autonomic) After following oculomotor nerve, synapse on ciliary ganglion
What do post ganglionic parasympathetic axons of the oculomotor nucleus supply?
Ciliaris
Pupillary constrictor
True or false opthalmic nerve fibers pass through the ciliary ganglion without synapsing
True
Where is the trochlear nucleus located? What is unique about the trochclear nerve’s apparent origin
In periaqueductal gray of the midbrain (just like oculomotor nucleus)
It is unique because it is only CN with apparent origin posterior midbrain
What part of the cerebral cortex sends axons to the trochlear nucleus
Brodmann area 8
Superior colliculi
Median longitudinal fissure
After exiting CNS trochlear nerve curves around the brainstem and enters the orbit where?
Superior orbital fissure
True or false; the trochlear nerve has communication with the cavernous plexus (sympathetic fibers)
True
What connection is there between the name “trochlear” nerve and what it supplies
it supplies the superior oblique muscle (cheaters muscle) which has a pulley-like mechanism on the medial aspect of orbit
What CN nucleus is located on caudal part of pons, on the floor of the rhomboid fossa
CN VI the abducens
Where does the abducens nerve receive information from?
Brodmann area 8
Superior colliculi
Median longitudinal fissure
After penetrating the dura and traveling along the cavernous sinus where does the abducens nerve exit the skull
Superior orbital fissure
What is strabismus (internal and external)
Internal strabismus: eyes cross
External strabismus: eyes are directed away from each other
What is diplopia
While making patient cover one eye and look at eye chart
They report double vision (no way to prove, it is subjective; on word of patient)
What is Ptosis
Eyelid droops due to weakness of levator palpebrae superioris (oculomotor nerve lesion may be the cause)
What would you expect to see in a patient with oculomotor paralysis - external ophthalmoplegia
Diverging strabismus (eye cross) Diplopia (double vision eye exam) Ptosis (eyelid droop)
What would you expect to see in a patient with oculomotor paralysis - Internal ophthalmoplegia
Would involve inability to constrict pupil as well as loss of light and accommodation reflexes
What are some possible etiologies of oculomotor paralysis
aneurysms, or diabetes
Is trochlear nerve paralysis common? What are the symptoms?
No, it is rare Internal strabismus (converging eyes), inability to look down (consequently trouble descending stairs)
Is abducens paralysis common? What are some symptoms?
yes, it is most common of the eye nerves Internal strabismus (converging eyes), can't move eye laterally, Diplopia (double vision when eye exam)
True or False; the trigeminal nerve is a mixed nerve with many more sensory fibers than motor
True
What are the 3 nuclei or termination (sensory) associated with the trigeminal nerve
Main sensory nucleus
Spinal nucleus
Trigeminal mesencephalic (near midbrain)
What is the nucleus of origin for the trigeminal nerve
Trigeminal motor nucleus
What is the peripheral ganglion associated with the trigeminal nerve
Trigeminal (semilunar) ganglion
Cell bodies in the sensory pathway of the trigeminal are located where?
Trigeminal (semilunar) ganglion
Peripheral processes from face travel to this ganglion
Where do central processes from the trigeminal ganglion go from the Trigeminal (semilunar) ganglion
They enter CNS go to main trigeminal nucleus (for touch, vibration, joint proprioception) or to the spinal nucleus (pain and temperature)
What spinal tracts are the central processes from the trigeminal ganglion to the main trigeminal nucleus or spinal nucleus akin to
The main trigeminal: are like gracilis and cunatus
Spinal: like lateral spinal thalamic
What is the only pathway to have sensory cell bodies located in the CNS?
Mesencephalic nucleus of the trigeminal
Describe the pathway for fibers going to the mesencephalic nucleus of the trigeminal
Dendrites travel from the periphery pass THROUGH the trigeminal nucleus and enter the CNS to the mesencephalic nucleus
What is unique about the mesencephalic nucleus of the trigeminal
It is the only pathway in the body to have sensory fibers located IN the CNS
What is the only branch of the trigeminal to carry motor fibers?
Mandibular
Motor fibers leave the CNS by traveling through the trigeminal nucleus with the mandibular branch
What are the 6 areas the mandibular (motor) branch of the trigeminal receives information from?
Cerebral cortex (both hemispheres) Reticular formation Red nucleus Tectum Medial longitudinal fasciculus (MLF) Mesencephalic nucleus (monosynaptic reflex)
Where is the apparent origin of the trigeminal nerve
lateral aspect of the pons
After the trigeminal nerve leaves the lateral aspect of the pons, it travels anterior ward and enters a pouch of dura called what?
Trigeminal (Meckel’s) cave
Where do the 3 branches of the trigeminal come off?
In the Trigeminal (Meckel’s) cave
Where does the opthalmic division of trigeminal enter the skull
Through the SOF just like CN III, IV, and VI
True or false; the opthalmic division of trigeminal nerve is a mixed nerve
False, it is only sensory in function
In addition to carrying sensation from skin over nose, forehead and scalp the opthalmic division of trigeminal carries sensation from where?
Mucous membranes in frontal and sphenoid sinuses and membrane covering nasal septum
What are the 4 branches given off the opthalmic division of trigeminal
Meningeal nerve, Lacrimal, Nasociliary and Frontal
Men Lack Nothing Familiar
What branch of the opthalmic division of the trigeminal is given off before entering the SOF? What does it supply
The meningeal branch
Dura lining middle cranial fossa
What is the smallest branch of the opthalmic division of trigeminal? What does it supply?
Lacrimal
Lacrimal gland (sensory only)
*Also carries some parasympathetic fibers (secretory) originating from CN VII pterygopalatine ganglion
What is the largest branch of the opthalmic division of trigeminal? What does it branch into? What does it supply?
Frontal nerve
Supratrochlear nerve: sensation from medial corner of eye
Surpaorbital: sensation from conductive, upper eyelid and forehead-mucus membrane lining frontal sinus
What is the branch of the opthalmic division of trigeminal that branches 3 times and has two terminal branches? What are these branches?
nasociliary nerve
3 branches:
communicating branch to ciliary ganglion
Long ciliary nerve supplies the eyeball
Posterior ethmoid nerve-sensation from sphenoidal and ethmoidal sinuses
2 terminal branches:
Anterior ethmoid- supplying skin over nose mucus membrane anterior part nasal septum
Infrotrochlear-supplying medial corner of eye-includes lacrimal sac
True or False; the maxillary division of trigeminal is sensory only
True
Where does the maxillary division of trigeminal enter the pterygopalatine fossa?
foramen rotundum (round foramen)
What sensory function does the maxillary division of trigeminal supply?
skin between eyes and mouth, over cheeks and temples, mucosa lining the maxillary sinuses, nasal conchae, palate and gingiva
What are the 4 branches of the maxillary division of trigeminal?
Middle meningeal nerve, Zygomatic nerve, two or three ganglionic branches, and infraorbital nerve
What is the only branch of the maxillary division of trigeminal to branch off before exiting the round foramen? What does it supply?
middle meningeal nerve- meninges of the middle cranial fossa
What branch of the maxillary division of trigeminal has 3 branches supplying skin over the face? What are they? What do they supply?
Zygomatic nerve
Communicating branch-postganglionic parasympathetic fibers to pterygopalatine ganglion to lacrimal gland
zygomaticotemporal nerve- skin over the temple
zygomaticofacial nerve- skin over the cheek
What do the two or three ganglionic branches of the maxillary division of trigeminal supply?
sensory information from the upper pharynx, nasal cavity, and palate through the pterygopalatine ganglion (NO SYNAPSE) to maxillary division
What branch of the maxillary division of trigeminal gives off 3 branches that supply teeth? What are these branches called?
Infraorbital nerve
Anterior, Middle, and Posterior alveolar nerves
Infraorbital nerve also supplies lower eyelid and maxillary sinus
True or False; branches of the maxillary division of trigeminal distribute postganglionic parasympathetic fibers from the pterygopalatine ganglion
True
True or False; postganglionic sympathetic fibers from the superior cervical ganglion pass through the pterygopalatine ganglion
True
Where does the mandibular division of the trigeminal exit the skull?
Foramen ovale
True or false; the mandibular division of trigeminal is a mixed nerve
True
What are the 4 muscles of mastication that the mandibular division of trigeminal supplies?
Masseter, Temporalis, Medial and Lateral pterygoid
The recurrent meningeal branch (nervous spinosum) is a branch of the mandibular division of trigeminal, what is unique about its course? What does it supply?
It branches off the mandibular division after V3 has left the skull, then the recurrent meningeal branch reenters the skull
Supplies dura of middle cranial fossa and anterior cranial fossa and calvarium
The medial pterygoid nerve, which is a branch of the mandibular division of trigeminal is the motor supply to what muscle? It gives rise to fibers that travel through where and supply what?
Supplies medial pterygoid muscle
Travels through Otic ganglion, supplies tensor veli palatine and tensor tympani
When the mandibular division of trigeminal divides into a anterior and posterior division are both divisions still mixed?
Not really, the anterior is predominantly motor and the posterior is predominantly sensory
The anterior division of the mandibular division of trigeminal gives rise to what 4 nerves
Masseter nerve
Deep temporal nerve
Lateral pterygoid nerve
Buccal nerve
In addition to the masseter nerve (branch off of the anterior division of the mandibular division of trigeminal) supplying motor information for the masseter muscle, what else does it supply?
sensory information from temporomandibular joint
True or False; the deep temporal nerve (a branch of the anterior division of the mandibular division of trigeminal) gives off two branches each of which supply the temporalis muscle
True
True or false; the buccal nerve (a branch of the anterior division of the mandibular division of trigeminal) is sensory only in function
True
What does the buccal nerve (a branch of the anterior division of the mandibular division of trigeminal) supply/
Sensory from cheek (skin and mucosal) and buccal gingivae of molars
Which is bigger the anterior division or posterior division of the mandibular division of trigeminal
Posterior division
What are the 3 nerves given off the posterior division of the mandibular division of trigeminal?
Auriculotemporal nerve
Lingual nerve
Inferior alveolar
What are the 2 autonomic ganglia associated with the posterior division of the mandibular division of trigeminal?
Submandibular ganglion
Otic ganglion
True or false; the auriculotemporal nerve (a branch of posterior division of the mandibular division of trigeminal) passes through parotid gland as it carries sensory info from skin of temple and ear
True
The auricotemporal nerve (a branch of the posterior division of the mandibular division of trigeminal) carries some post-ganglionic parasympathetic fibers from what ganglion?
Otic ganglion
The lingual nerve (a branch of the posterior division of the mandibular division of trigeminal) combines with this branch of CN VII in the infra temporal fossa
Chorda tympani
True or false; the inferior alveolar nerve (a branch of the posterior division of the mandibular division of trigeminal) is a mixed nerve
True
The inferior alveolar nerve (a branch of the posterior division of the mandibular division of trigeminal) has two sensory branches, what are they? What do they supply?
Incisive branch and mental nerve
Incisive-supplies incisors, canines, and 1st pre-molars
Mental-labial gingivae adjacent incisors and skin of lower lip and chin
What do the motor fibers from the inferior alveolar nerve (a branch of the posterior division of the mandibular division of trigeminal) supply?
Mylohyoid and ANTERIOR belly of digastric
The submandibular ganglion receives what kind of fibers from CN VII?
Pre-ganglionic fibers after lingual nerve combines with chorda tympani
The Otic ganglion sends fibers to where? What kind are they?
Post-ganglionic (parasympathetic) fibers to the parotid gland
What is Trigeminal neuralgia
Facial pain “described as worst pain of life”