Exam 1 Flashcards

1
Q

Adipose Tissue

A

Vascular loose connective tissue that stores fat and provides energy, cushioning and insulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Basement Membrane

A

Thin, acellular layer separating the epidermis from the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Blisters

A

Collection of fluid at the junction between the dermis and epidermis due to friction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Callus

A

Localized buildup of the stratum corneum cells due to pressure or friction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Collagen

A

main structural protein of the various connective tissues in animals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dermal Papillae

A

The ridges and valles of the superior surface of the dermis that conforms with the contours of the epidermal stratum basale to help anchor the two layers together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Elastin

A

protein in connective tissue that is elastic and allows many tissues in the body to resume their shape after stretching or contracting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Epidermis

A

Outer, avascular layer of skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Fascia

A

Fibrous connective tissue that separates and surrounds structures and facilitates movement between adjacent structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Fibroblasts

A

Dermal cell that produces collagen, elastin, granulation tissue and growth factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Full-thickness Wound

A

Wound that extends through the epidermis and dermis and into or through the subcutaneous tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Hair

A

Epidermal appendages located within the dermis that are made of soft keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Histamine

A

Chemical mediator released by mast cells that causes vasodilation, increases vessel wall permeability, and attracts other cells to the area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Keratin

A

A protein produced by keratinocytes. Nails are made of hard keratin; hair is made of soft keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Keratinocytes

A

Epidermal cell that resurfaces a wound and produces keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Langerhan’s Cells

A

Epidermal cells that assist with infection control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Macrophages

A

Cell that directs the repair process, secretes growth factors and enzymes and destroys bacteria and debris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Mast Cells

A

Cell that helps initiate inflammation, secretes histamine, enzymes, and chemical mediators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Melanin

A

Pigment produced by melanocytes that helps protect the body from UV radiation, and is a major determinant in skin color

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Melanocytes

A

Pigment producing cells within the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Merkel Cells

A

Sensory receptor within the epidermis providing information on light touch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Nails

A

Epidermal appendage made of hard keratin and located at the dorsal tips of digits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Open Wound

A

Damage to the skin resulting in a loss of skin integrity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Papillary Dermis

A

Thin superficial dermal layer consisting of loosely arranged connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Partial-Thickness Wound

A

Wound involving the epidermis and part of the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Phagocytizing

A

Process of engulfing and destroying bacteria or debris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Rete pegs

A

Protrustions of the epidermal stratum basale that extends into the papillary dermis to help anchor the two layers together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Reticular Dermis

A

Thick, deep dermal layer consisting of dense, irregularly arranged connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Sebaceous Gland

A

Oil gland, epidermal appendage located within the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Sebum

A

Oily substance that lubricates the skin and hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Stratum Basale

A

Deepest epithelial cell layers, contains continuously dividing cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Stratum Corneum

A

Outermost epithelial cell layer, consists of dead keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Stratum Granulosum

A

Epithelial cell layer located between the stratum spinosum and straum lucidum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Stratum Lucidum

A

Epithelial cell layer located between the stratum corneum and stratum granulosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Stratum Spinosum

A

Epithelial cell layer located between the statum basale and stratum granulosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Subcutaneous Tissue

A

Composed of adipose tissue and fascia; located beneath the dermis; helps support the skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Sudoriferous Glands

A

Sweat glands, epidermal appendage located within the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Superficial Wound

A

Wound involving only the epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

White Blood Cells

A

Cell that helps fight infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

CHAPTER 2: Wound Healing

A

Wound Healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Abrasion

A

Wound caused by scraping or friction to the skin’s surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Angioblasts

A

Endothelial cell that lines vessel walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Angiogenesis

A

Formation of new blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Chemotactic agents

A

Substance that attracts cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Chemotaxis

A

Movement along a chemical gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Closed wound

A

A wound in which the epithelial integrity has been restored

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Collagenases

A

Enzyme that breaks down collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Contracture

A

Pathological shortening of scar tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Current of Injury

A

Local change of polarity at the site of integument injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Cytokines

A

Signaling protein during the inflammatory phase of would healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Cytotoxic Agents

A

Substance that is poisonous to human cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Dehiscence

A

Separation of wound margins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Delayed Primary Closure

A

A combination of primary and secondary wound healing processes in which the wound is first observed before primary closure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Diapedesis

A

The movement of PMNs through capillary walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Epibole

A

Keratinocyte migration over the lip or margin of the dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Epithelialization

A

Process by which keratinocytes resurface the wound defect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Exudate

A

Mixture of fluid, high levels of protein and cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

Fibroblast

A

Dermal cells that produce collagen, elastin, granulation tissue and growth factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Granulation Tissue

A

Temporary structure composed of vascularized connective tissue that fills the wound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

Growth Factors

A

Growth promoting substance that increases or enhances cell size, proliferation or activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Healed Wound

A

A closed wound with tissue strength approaching normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

Histamine

A

Chemical mediator released by mast cells that causes vasodilation, increases vessel wall permeability, and attracts other cells to the area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

Hypergranulation

A

Error of the proliferative phase in which too much granulation tissue is formed and epithelialization is delayed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

Hypertrophic Scarring

A

Overproduction of collagen that stays within the confines of the original wound

65
Q

Hypogranular

A

A pothole-type wound that fails to build a sufficient granulation tissue matrix

66
Q

Inflammation

A

First phase of wound healing, characterized by rubor, calor, tumor, dolor, functionlaesa; vascular and cellular response to injury of living tissue

67
Q

Integrins

A

Cell surface receptors that allows cells to reversibly bind to the extracellular matrix

68
Q

CHAPTER 3: FACTORS AFFECTING WOUND HEALING

A

Factors Affecting Wound Healing

69
Q

Acute Wound

A

A wound induced by surgery or trauma in an otherwise healthy individual

70
Q

Chronic Wound

A

A wound, induced by various causes, whose progression through the phases of wound healing is prolonged or arrested

71
Q

Colonization

A

Normal presence of a small number of microbes (<= 10^3 organisms/gram of tissue)

72
Q

Infection

A

Invasion and multiplication of migroorganisms within body tissues, wound cultures reveals greater than 10^5 microbes/gram of tissue

73
Q

Macerated

A

Skin is white, friable, overhydrated and wrinkled

74
Q

Necrotic

A

Dead, devitalized tissue adhered to the wound bed

75
Q

CHAPTER 4: EXAMINATION OF PATIENTS WITH OPEN WOUNDS

A

Examination of Patients with Open Wounds

76
Q

Capillary Refill

A

Indicator of surface blood flow. Normally less than 3 seconds.

77
Q

Eschar

A

Black necrotic tissue that may either be soft of hard

78
Q

Induration

A

Firm edema

79
Q

Pitting Edema

A

Swelling in which a depression remains within the involved tissues after the application of digital pressure

80
Q

Semmes-Weinstein Monofilaments

A

Tools used to assess sensory integrity

81
Q

Sinus Tract

A

An elongated cavity or abscess that drains to the body surface, may be associated with category/stave IV pressure ulcers

82
Q

Slough

A

Necrotic tissue that is yellow or tan in color and has a stringy or mucinous consistency

83
Q

Tunneling

A

A narrow passageway within a wound bed

84
Q

Undermining

A

Area of tissue under the wound edges that becomes eroded, resulting in a large wound with a small opening

85
Q

CHAPTER 5: DEBRIDEMENT

A

Debridement

86
Q

Autolytic Debridement

A

Form of debridement that uses endogenously produced enzymes to digest necrotic tissue

87
Q

Biologic Debridement

A

The use of sterile maggots to debride the wound

88
Q

Debridement

A

The removal of necrotic tissue, foreign material and or debris from a wound bed

89
Q

Enzymatic Debridement

A

Form of debridement using topically applied exogenous enzymes to remove devitalized tissue; requiring physician’s prescription

90
Q

Incision and Drainage

A

Procedure in which an abscess is surgically opened and thoroughly irrigated

91
Q

Mechanical Debridement

A

Form of debridement using force to remove devialized tissue, foreign material, and debris from a wound bed

92
Q

Nonselective Debridement

A

The removal of non specific areas of devitalized tissue. May include mechanical or surgical debridement

93
Q

Selective Debridement

A

Removal of specific areas of devitalized tissue, may include sharp, enzymatic or autolytic debridement

94
Q

Selective Sharp Debridement

A

Form of sharp debridement using scissors or scalpel to cut along the lines of demarcation between viable and nonviable tissue

95
Q

Serial Instrumental Debridement

A

Form of sharp debridement using forceps and scissors to remove loosely adherent devitalized tissue. Usually occurs over a number of visits and may require prior tissue prep

96
Q

Sharp Debridement

A

Selective debridement using forceps, scissors, or a scalpel

97
Q

Surfactants

A

Cytotoxic substances within wound cleansers that lower surface tension of loose particulate matter on a wound bed

98
Q

Surgical Debridement

A

The use of scalpels, scissors, or lasers in a sterile environment by a physician by a podiatrist to remove necrotic tissue, foreign material and debris from wound beds

99
Q

Wet-to-Dry Dressing

A

Not used much. Consist of moistened gauze placed in or on a wound, left until dry and then removed

100
Q

Wound Cleanser

A

Commercially available antiseptic containing surfactants. Not regulated by FDA

101
Q

Wound Cleansing

A

The delivery of a wound cleanser to the wound surface using mechanical force to remove lightly adhered necrotic tissue, debris and bacteria

102
Q

Wound Scrubbing

A

Mechanical debridement using a sponge, brush or gauze along with a fluid to break the adherence of devitalized tissue and debris from the wound bed

103
Q

CHAPTER 17: BASIC DERMATOLOGY

A

Basic Dermatology

104
Q

Abscess

A

Localized collection of purulent material in a cavity formed by necrosis and disintegration of tissues

105
Q

Alopecia

A

Absence of hair in normally hairy areas of skin

106
Q

Aphtha

A

Small ulcers of the mucous membranes

107
Q

Bulla

A

A rounded or irregularly shaped blister greater than .5 cm in diameter, containing serous or seropurulent material

108
Q

Burrow

A

Small and short (as in scabies) or long and tortuous tunnels in the epidermis

109
Q

Carbuncle

A

Necrotizing infection of the skin and subcutaneous tissues composed of a group of furnuncles (boils)

110
Q

Cellulitis (Erysipelas)

A

Inflammation of cellular tissue, purulent inflammation of the dermis, subcutaneous tissue and soft tissues

111
Q

Comedo/Comedones

A

Plug of keratin and sebum in an orifice, blackhead

112
Q

Crusts

A

Dried blood, serum or pus mixed with epithelial and bacterial debris

113
Q

Cutaneous Horn

A

Localized spike-shaped area of marked overgrowth of keratin; can stick out above the skin a half an inch or more

114
Q

Denune

A

Loss of epidermis

115
Q

Ecchymosis

A

A macular red or purplish-blue hemorrhage in the skin or mucous membrane more than 2 cm in diameter

116
Q

Erosion

A

Loss of all or potions of the epidermis; heals without scar tissue

117
Q

Erythroderma

A

A generalized redness of the skin

118
Q

Excoriation

A

Linear of punctate abrasion produced by mechanical trauma

119
Q

Fibrosis

A

Formation of excessive fibous collagen in the tissues

120
Q

Fissure

A

Linear crack or cleft through the epidermis and often into the dermis

121
Q

Follicular Plugs

A

Keratin plugs in the hair follicle 1-3 mm in size

122
Q

Furnuncle

A

A localized pygoenic infection originating in a hair follicle

123
Q

Granuloma

A

Chronic inflammatory tissue composed of macrophages, fibroblasts, and granulation tissue

124
Q

Keratoderma

A

Hyperplasia of the stratum corneum

125
Q

Keratosis

A

Horny thickening of the skin

126
Q

Kerion

A

Nodular inflammatory, pustular lesion due to fungal infection

127
Q

Lesion

A

Pathological or traumatic loss of normal tissue continuity, structure, or function

128
Q

Lichenification

A

Chronic thickening of the epidermis with exaggeration of its normal markings, often from excessive rubbing or scratching

129
Q

Macule

A

Small, circumscribed change in skin color, nonpalpable, present in various shapes

130
Q

Malperforans Ulcer

A

Seen in diabetics and Hansen’s disease: associated with neuropathy so the ulcers are painless yet deep and destructive

131
Q

Milia/Milium

A

Whitish papules, 1-2 mm in diameter with no visible opening onto skin surface

132
Q

Necrobiosis

A

Describes partial degeneration of tissue

133
Q

Nodule

A

Papule greater than 1 cm in diameter, deeper and firmer than a papule; centered in the dermis or subcutaneous adipose

134
Q

Papilloma

A

Benign tumor projecting from the skin

135
Q

Papule

A

Circumscribed, solid elevations up to .5 cm in diameter, present in various shapes

136
Q

Patch

A

Macule greater than 1 cm in diameter

137
Q

Petechia

A

Punctate hemorrhage spot 1-2 mm in diameter

138
Q

Plaque

A

Papule greater than .5 cm in diamter; often formed by coalescence of papules, generally flat but may have central depressions

139
Q

Poikiloderma

A

Dermatosis characterized by variegated cutaneous pigmentation, atrophy and telangiectasia

140
Q

Primary Lesion

A

Lesion that appears first

141
Q

Pruritus

A

Irritating skin sensation that elicits the scratch response; itch

142
Q

Pupura

A

Discoloration of the skin and mucosa due to extravasation of blood

143
Q

Pustule

A

Small elevations of the skin containing purulent material

144
Q

Rash

A

Temporary eruptions of the skin

145
Q

Scales

A

Dry or greasy laminated masses of keratin

146
Q

Scar

A

Collagen and connective tissue that replaces lost dermis

147
Q

Sclerosis

A

Hardening or induration of the skin often due to fibrosis

148
Q

Secondary Lesion

A

Primary lesion that has been modified by trauma, regression or other extraneous factors

149
Q

Sinus

A

Cavity of channel in the tissue

150
Q

Stria Cutis Distensae

A

A band or streak of linear, atrophic, pink, white, or purple lesions of the skin due to changes in connective tissue

151
Q

Sycosis

A

Chronic pustular folliculitis and perifolliculitis involving the beard area

152
Q

Telangiectasia

A

Visible vascular lesion formed by dilation of small cutaneous blood vessels

153
Q

Tumor

A

Soft or firm, movable or fixed mass of various shape, larger than 2 cm

154
Q

Vegetation

A

A growth of pathological tissue consisting of multiple closely set papillary masses

155
Q

Verruca

A

Epidermal tumor caused by a papillary virus, describes lesion with a warty surface

156
Q

Vesicle

A

Circumscribed, fluid containing, epidermal elevation 1-10 mm in size

157
Q

Vibex

A

A narrow linear mark; usually hemorrhage from scratching

158
Q

Wheal

A

Localized skin edema of irregular shape and variable size that is transient and superficial

159
Q

Xerosis

A

Dryness of the skin, usually presents and scaling, superficial fissures and pruritus