Exam 1: 2 Flashcards
Describe the way a computer searches to identify articles
Title of the article should reflect what’s in the article, but it might not always do this, it shows key words after the abstract
evidence pyramid
- meta analysis
- systematic review (of RCTs)
- RCT (gold standard)
- cohort studies
- case control studies
- case series/case reports
- clinical experience
- animal research
Peerreviewed/juried/refereed
one’s professional colleagues evaluate in regards to quality and credibility of the article
nonpeer reviewed/nonjuried/Nonreferred
‘publications’ that one can write about whatever they want and it often gets published” so be careful and aware of where you’re getting your information
Which publications serve as a greater source of info for patient management generally?
nonrefereed
filtered studies
evaluated along with multiple similar studies by someone other than the researcher and then combined with those studies to form a comprehensive review of outcomes for a particular topic
published studies have been appraised for quality and their ability to be used as references to influence clinical practice
examples of filtered studies
- CAT
- systematic reviews
- meta analyses
- critically appraised individual articles
purpose of filtered studies
condense the enormous number of related study outcomes on a topic
unfiltered studies
methods are not evaluated piece by piece in combination with other studies
examples of unfiltered studies
published studies in the primary literature, including:
- case series reports
- cohort studies
- RCTs
search engines for identifying research evidence
- PubMed (MEDLINE)
- Cochran database
Which is the primary source for clinical effectiveness information?
Cochran database
CAT validation process
- Was the CAT focused by a well built question?
- What was the explicit process used to ID and select the evidence?
- Is it unlikely that relevant studies were missed?
- Was the evidence appraised the best available to answer the question?
- Were the appropriate validity criteria applied?
- Are the dates clearly stated?
- What is the CATs message? How strong is it? Is it expressed in terms
that will be helpful? Will the message help me in my care of patients? Can I apply the message to my setting and/or patients? Were all clinically important outcomes/benefits/harms discussed? - Criteria for authority of authors, disclosure of competing interests, and feedback mechanisms were these discussed?
PEDro
- dedicated PT database
- has scoring system
- most common device used
PEDro scale: know at least 5
- random allocation of subjects to groups
- allocation was concealed
- baseline characteristics similar between groups
- blinding of all subjects
- blinding of therapists
- blinding of all outcome assessors
- at least 85% followup
- intention to treat analysis
- between group stat comparison
- point estimates and measure dispersion
(not scored): eligibility criteria were specified