Exam 1 Flashcards
neurons
basic signaling unit
glial cells
don’t construct signals but serve various functions, provide support, electrical stimulation
oligondendrocytes
myelinate axons in brain and spinal cord
schwann cells
myelinate axons in periphery of body
microglial cells
act as immunte cells in CNS, remove damaged cells
dendrites
neuron part that receives input from other neurons
axons
neuron part that transmits electrical signals - axon terminal releases chemicals to communicate with other neurons
neuron signaling
recieve, evaluate, transmit info, transmission at synapse and most are pre and post synaptic
node of raniver
gaps in myelin, regeneration of action potential happens here through voltage gated ion channels
within neuron, between neuron
electrical, chemical
membrane potential resting state
-70mV
action potential
rapid depolarization and polarization of a small region of the membrane on a neuron’s output via its axon by the opening and closing of an ion channel
all or none law (0 or 1)
either neuron fires or it doesn’t
rate of firing
how neurons process info, speed for regeneration of action potentials is limited to about 200/ms, intensity of stimulus is coded by it
neuronal recording, single unit
how to monitor action potential
grey matter
composed of neuronal cell bodies
white matter
consists of axons and glial cells
corpus callosum
white matter structure in brain that connects L and R hemispheres
brainstem
medulla and pons and cerebellum and midbrain
cerebellum
maintain posture, walking, coordinated movement
thalamus
gateway of sensory information and sensory modalities (except olfactory) make synaptic relays in thalamus before being routed to primary sensory area
prefrontal cortex
does executive functions, higher order cognitive functions, center of cognitive control
cognitive psychology
identify internal processes for observable behaviors, mental representations and internal transformations
mental representations
internal pictures
internal transformations
stages of memory that are encoding, comparing, deciding, and responding
word superior effect
detect stimuli better when recognizable, people can recognize when presented with words as opposed to alone or with nonword strings
alzheimer’s disease
risk increases by age, degenerative, large jump at 65+
epilepsy
excessive and abnormal patterned activity in brain, seizure when transient loss of consciousness
double dissociation
offer strongest neuropsychological evidence that a patient has a selective deficit of a certain cognitive function, lesion in area X impairs ability to do A but not B and lesion to Y impairs ability to do B not A
agonist
chemical substance that binds to and activate a receptor causing a bio response ex:Ldopa
antagonist
chemical substance that binds to and blocks activation of certain receptors preventing bio response ex:halperidol
behavioral genetics
study how genetic info shapes individual behaviors, use knockout procedure
knockout procedure
inactivating certain gene, helps with behvioral genetics
DBS - deep brain stimulation
surgical implants of microelectrodes directly in the brain
optogenetics
use light to manipulate neural activities, increase or decrease it, viral transduction then protein responds to specific light frequency, opening/closing ion channels
TMS - transcranial magnetic stimulation
noninvasive stimulation method, application of magnetic field to portion of the scalp to temporarily deactivate neurons below magnet (virtual lesion) – repetitive TMS or continuous
event related potentials
align trials relative to event, see stimulus and only look at after stimulus onset
PET - positron emission tomography
invasive, because it uses radioactive tracers (not noninvasive like MRI), measure metabolic activity by monitoring distribution of a decaying injective radioactive tracer