Exam 1 Flashcards
Treatment goal for dyslipidemia
Greater than or equal to 50% reduction in LDL
Preferred treatment for dyslipidemia
-Lifestyle modifications
-Low (<7%) saturated fat; Low (<200 mg/dL) C
-Moderate-High intensity statin
Treatment goal for HTN
BP < 130/80 mmHg
Preferred treatment for HTN
-Lifestyle modification
-Therapy based on compelling indications with BB, ACEi, ARBs + others as needed
Treatment goal for DM
HbA1c < 7%
Treatment preferred for DM
-Individualize to reach goal
-T2DM with ASCVD: SGLT2 or GLP-1
Treatment goal for smoking
Complete smoking cessation/exposure
Preferred treatment for smoking
Systematic strategy, pharmacotherapy
Treatment goal for weight management
-BMI: 18.5-24.9
-Waist circumference: 40 for men and 35 for women
-Wt loss 5-10% initially
Preferred treatment for weight management
Diet/lifestyle counseling; printed educational materials and encourage
Treatment goal for physical activity
~30-60 min mod intensity activity 5-7 days/wk
~cardiac rehab/supervised
Preferred treatment for physical activity
Brisk walking, swimming, cycling; increased daily activities
Why is it not recommended to give low-dose ASA in patients who have no risk of CAD?
Greater risk of developing hemorrhagic stroke (risk outweighs potential benefit)
Which P2Y12 inhibitor is indicated following ACS
Cangrelor or Prasugrel
Which P2Y12 inhibitor is indicated following ACS or prior MI
Ticagrelor
What is the purpose of enteric coated ASA?
Protect gastritis/stomach ulcer irritation
For a patient having an MI, take ____ in addition to NGL
1 ASA tablet (can chew and swallow to help it be absorbed faster)
____-dose ASA reduces risk of future ____ substantially
Low; MACE
Which P2Y12 inhibitors are pro-drugs
Clopidogrel and Prasugrel
What is the time to peak inhibition for clopidogrel
4-5 h (300 mg); 2-3 h (600 mg)
What is the time to peak inhibition of prasugrel
2-4 h
What is the time to peak inhibition of ticagrelor
2-4 h
What is the time required for effect dissipation for clopidogrel?
5 d
What is the time required for effect dissipation for prasugrel?
7 d