Exam 1 Flashcards
What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?
Haloperidol (Haldol)
Chlorpromazine (Thorazine) Thioridazine (Mellaril) Perphenazine (Trilafon) Trifluoeerazine (Stelazine) Fluphenazine (Prolixin)
Loxapine (Loxitane)
Molindone (Moban)
- Schizophrenia
- 1st Generation
- Treat + S&S
What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Do they treat + or - S&S?
Aripiprazole (Abilify)
Clozapine (Clozaril)
Quetiapine (Seroquel)
Olanzapine (Zyprexa)
Asenapine (Saphris)
Risperidone (Risperdel) Paliperidone (Invega) Ziprasidone (Geodon) Iloperidone (Fanapt) Lurasidone (Latuda)
- Schizophrenia
- 2nd Generation
- Both + & - S&S
Which Generation of drugs for Schizophrenia cause MORE Extrapyramidal Side Effects (EPS)?
What are those Symptoms?
-1st Generation
- Pseudoparkinsonism
- Acute Dystonic Reactions
- Akathisia
- Tardive Dyskenesia
- Anticholenergic (↑ in 1st gen but also in 2nd gen)
What is Pseudoparkinsonism?
What is used to Treat it?
-S&S of 1st gen drugs that Mimic Parkinsons; Mask like face, Shuffling gate, Stiff/Stooped Posture, Drooling, Tremor, Pill Rolling.
- Artane,
- Benztropine (Cogentin)
What is an acute Dystonic Reaction?
What is used to treat it?
- S&S of 1st gen drugs; Contraction of tongue/jaw, face, neck, back.
- 2 types: Opisthotonos, Oculogyric Crisis
-Drugs: Benadryl, Benztropine (Cogentin)
What is Akathisia?
What is used to treat?
- S&S of 1st gen Drugs; Incessant fidgeting/rocking
- Drugs: Propranolol (Inderal), Lorazepam (Ativan), Diazapam (Valium)
What is Tardive Dyskinesia?
What is used to treat?
- S&S of 1st gen drugs; excessive Facial fidgeting r/t mouth/tongue; Choreic movements in limbs (Rapid irregular movements/Jerky), Athetoid Limb movements (Slow Serpentine like movements), Pelvic Thrusts
- No Known Treatment; Screening Q3mths (AIM Scale)
What is Neuroleptic Malignant Syndrome?
What is used to Treat it?
-SE of 1st gen Drugs; Increased autonomic System S&S: Increase RR, HR, Temp, HTN, Diaphoresis (Sweating), Rigidity
-Bromocriptine (Parlodel) Used 1st
Dantrolene (Dantrium) Used 2nd
What are the Anticholergenic S&S?
- “Can’t see, Can’t Pee, Can’t spit, Can’t Shit”
- Dry mouth, urinary retention, constipation, blurred vision, photo-sensitivity, dry eyes, Impotence
—Adjuncts to Antipsychotic Medications—
Valium, Ativan, Xanex, and Librium are all examples of what category of drug?
______ is a Mood Stabilizer.
What other category of drug is used as an adjunct?
- Benzodiazapines
- Lithium
- Antidepressants/SSRI’s used to treat Depression in Schizo Pt’s
What are the 4 A’s for Alzheimers??
- Amnesia (Memory loss)
- Aphasia (Loss of Language ability)
- Apraxia (Loss of learned motor skills (arms in pants)
- Agnosia (don’t recognize the familiar; senses)
What are these drugs used for??
Catagory and action?
Razadyne
Excelon
Aricept
Cognex (BAD S&S)
Namenda
- Alzheimer’s
- Cholinesterase Inhibitors
- Prevent Breakdown of acetylcholine
What Disorder do these drugs Tx?
Are these Drugs 1st or 2nd Generation?
Haloperidol (Haldol)
Schizophrenia
- 1st Generation
- Treat + S&S
Tx what?
1st or 2nd Generation?
Chlorpromazine (Thorazine)
Schizophrenia
- 1st Generation
- Treat + S&S
Thioridazine (Mellaril)
Tx what?
1st or 2nd Generation?
Schizophrenia
- 1st Generation
- Treat + S&S
Perphenazine (Trilafon)
Tx what?
1st or 2nd Generation?
Schizophrenia
- 1st Generation
- Treat + S&S
Trifluoeerazine (Stelazine)
Tx what?
1st or 2nd Generation?
Schizophrenia
- 1st Generation
- Treat + S&S
Fluphenazine (Prolixin)
Tx what?
1st or 2nd Generation?
Schizophrenia
- 1st Generation
- Treat + S&S