Exam 1

Question 1

Affinity

Answer 1

Extent or fraction to which a drug birds to receptors at any given drug concentration or the firmness with which the drug binds to the receptor

Question 2

Plateau or steady state

Answer 2

When the quantity of drug eliminated in the unit of time equals the quantity of the drug that reaches the systemic circulation in the unit of time

( Average amount in body stays stable)

Question 3

First-pass effect

Answer 3

When drug is rapidly metabolized in the liver during its first pass through in the blood

Creates no therapeutic effects

Question 4

Therapeutic objective of drug therapy