Exam 1 Flashcards

1
Q

what drug class is associated with the highest risk of withdrawal symptoms → leading to seizures + death?

A

benzos

never stop cold turkey

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Short-acting sedative-hypnotic sleep agents act on what?

A

gaba

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

meds to treat dramatic shifts in emotions, moods + energy levels. what’s an example?

A

mood stabilizers

ex: lithium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

therapeutic + toxicity levels for lithium.

A

therapeutic: 0.6-1.2
toxicity: > 1.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE of lithium toxicity (early) (2)

A

tremors + diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SE of lithium toxicity (late)

A

cognitive changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what should be monitored with lithium use?

A

1, thyroid fxn

  1. kidney fxn
  2. diet + fluids (remember that lithium acts as a salt, so dehydration could cause toxicity)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what SE should we teach about with anticonvulsants?

A

SJS!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is 1st line tx for depression?

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

remeron can help with what?

A

appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

2 main SE of antipsychotics (1st gen)

A
  1. EPS
  2. tardive dyskinesia (b/c these meds are working on dopamine = dopaminergic action) *

KNOW*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what kind of testing/monitoring should be used for antipsychotics (1st gen)?

A

AIMS testing (Abnormal Involuntary Movement Scale) + ongoing general monitoring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SE of antipsychotics (2nd gen)

A
  1. metabolic side effects (DM, hyperlipidemia, BMI changes)
  2. agranulocytosis → infection risk (specifically clozapine)
  • limited risk of EPS *
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what drugs decrease symptomatology w/o effects on movement?

A

2nd gen antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Primary NTs associated with ADHD drugs

A

norepi + dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

1st line tx/gold standard (for post school-age children) with ADHD

A

stimulants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

name some SE of stimulant ADHD meds (5)

A
  1. decreased appetite
  2. insomnia
  3. increased dopamine → psychosis risk
  4. alterations in anxiety
  5. “zombie look”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are 3 examples of psychiatric medications used in an emergency situation?

A

haloperidol (Haldol), olanzapine (Zyprexa) + ziprasidone (Geodon)

HOZ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Dr. T mentioned to NOT give 2 drugs together b/c of risk of cardiopulmonary arrest (give 1 hr apart). what are they?

A

olanzapine + lorazepam

Zyprexa + Ativan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

acetylcholine is associated mostly with which 2 things?

A

memory

movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

principle NT associated with alzheimer’s

A

acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

dopamine is associated mostly with which 2 things?

A

movement

reward center

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

too little dopamine is associated with which disorder?

what about too MUCH dopamine?

A

too little: parkinson’s

too much: schizophrenia

24
Q

norepinephrine is associated mostly with which 2 things?

A

alertness

awake/arousal

25
too little norepinephrine is associated with which condition?
depression
26
serotonin is associated mostly with which 2 things?
mood | sleep
27
what is the principle NT associated with depression + stress-related disorders?
serotonin
28
gaba is associated mostly with which 2 things?
awake/arousal | calm
29
which NT is mostly associated with anxiety disorders?
gaba
30
glutamate is associated mostly with which 2 things?
excitatory | memory
31
which NT is mostly associated with schizophrenia?
glutamate (also dopamine)
32
what medication class is decreasing dopamine → improves positive symptoms
antipsychotics
33
what things should we monitor for with antipsychotic use?
*movement disorders* -1st gen difficulty eating, breathing, talking, muscle changes (tightness, tremors), pain, dystonia metabolic issues -2nd gen agranulocytosis -clozapine
34
what is the monitoring protocol for clozapine?
1st 6 months: weekly blood monitoring f 2nd 6 months: biweekly monitoring (for agranulocytosis)
35
AE of SSRIs (4)
1. sexual dysfxn 2. insomnia 3. tremors 4. N/V
36
AE of SNRIs (5)
1. anxiety at start of therapy 2. tachycardia 3. dry mouth 4. N/V 5. fatigue
37
AE of TCAs (2)
1. anticholinergic SE | 2. suicidal thoughts
38
best patient education for MAOIs
dietary: avoidance of tyramine foods
39
how long should benzos be used? ideally
SHORT periods of time
40
things to monitor for with benzos
1. sedation 2. CNS effects 3. safety 4. dependence 5. overdose
41
what drug class can be used for PRN anxiety management? (safer/less dependence risk option)
antihistamines (hydroxyzine) *still some sedation, but not as pronounced as benzos*
42
neuroleptic malignant syndrome is associated with which drug class?
antipsychotics
43
SE of neuroleptic malignant syndrome (4)
1. fever 2. changes in LOC 3. HTN 4. sweating
44
what 3 scenarios can cause neuroleptic malignant syndrome?
1. titrating too quickly 2. switching meds 3. too high doses
45
serotonin syndrome is associated with which drug class?
anything that acts on serotonin and creates an environment where we have more of it (SSRIs, SNRIs)
46
SE of serotonin syndrome (5)
1. mental status change 2. hyperactivity 3. tremors 4. neuromuscular abnormalities 5. GI too much serotonin
47
tx for serotonin syndrome
1. stop med 2. treat symptoms 3. supportive therapies for the SE
48
what is the best model of care?
integrated
49
this model is patient centered and holistic. adjectives to describe it are empowered, strengths-based, peer support, respect, responsibility, hope....
recovery model
50
what are our vulnerable populations in mental health care?
older adults + children
51
reasons for involuntary admission
1. Mentally ill 2. Danger to self or others 3. Cannot meet basic necessities 4. Cognitive or substance challenges → may have to get court-ordered treatment **Does NOT mean patient loses their rights**
52
name these levels of prevention: - ongoing management - screening measures - education on mental health and wellness before any symptomatology
- tertiary - secondary - primary (our goal)
53
what is the evidenced-based 1st line tx for anxiety + depression? (not pharmacology)
cognitive behavioral treatment (CBT)
54
describe CBT
Exploring ways of thinking about problems and associated behaviors → transform maladaptive behaviors into healthy coping strategies
55
a person’s ability to cope + strategies they use to cope is referring to what?
resiliency
56
what should we be assessing with hallucinations?
1. are they command hallucinations? (telling patient to do something specific) 2. ask for content