Exam 1 Flashcards
what drug class is associated with the highest risk of withdrawal symptoms → leading to seizures + death?
benzos
never stop cold turkey
Short-acting sedative-hypnotic sleep agents act on what?
gaba
meds to treat dramatic shifts in emotions, moods + energy levels. what’s an example?
mood stabilizers
ex: lithium
therapeutic + toxicity levels for lithium.
therapeutic: 0.6-1.2
toxicity: > 1.5
SE of lithium toxicity (early) (2)
tremors + diarrhea
SE of lithium toxicity (late)
cognitive changes
what should be monitored with lithium use?
1, thyroid fxn
- kidney fxn
- diet + fluids (remember that lithium acts as a salt, so dehydration could cause toxicity)
what SE should we teach about with anticonvulsants?
SJS!
what is 1st line tx for depression?
SSRIs
remeron can help with what?
appetite
2 main SE of antipsychotics (1st gen)
- EPS
- tardive dyskinesia (b/c these meds are working on dopamine = dopaminergic action) *
KNOW*
what kind of testing/monitoring should be used for antipsychotics (1st gen)?
AIMS testing (Abnormal Involuntary Movement Scale) + ongoing general monitoring
SE of antipsychotics (2nd gen)
- metabolic side effects (DM, hyperlipidemia, BMI changes)
- agranulocytosis → infection risk (specifically clozapine)
- limited risk of EPS *
what drugs decrease symptomatology w/o effects on movement?
2nd gen antipsychotics
Primary NTs associated with ADHD drugs
norepi + dopamine
1st line tx/gold standard (for post school-age children) with ADHD
stimulants
name some SE of stimulant ADHD meds (5)
- decreased appetite
- insomnia
- increased dopamine → psychosis risk
- alterations in anxiety
- “zombie look”
what are 3 examples of psychiatric medications used in an emergency situation?
haloperidol (Haldol), olanzapine (Zyprexa) + ziprasidone (Geodon)
HOZ
Dr. T mentioned to NOT give 2 drugs together b/c of risk of cardiopulmonary arrest (give 1 hr apart). what are they?
olanzapine + lorazepam
Zyprexa + Ativan
acetylcholine is associated mostly with which 2 things?
memory
movement
principle NT associated with alzheimer’s
acetylcholine
dopamine is associated mostly with which 2 things?
movement
reward center