Ex 3. L7: Nanomedicine Flashcards

1
Q

Evolution of nanomedicine

A

COVID vaccine delivers nanolipid
-Small
-Cannot see with eyes
-Need electro microscope to visualize

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2
Q

Nanoparticulate drug carriers

A

-Micelles/polymeric micelles
-Liposomes
-Protein nanoparticles

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3
Q

Micelles

A

Surfactant molecules aggregate in aqueous solution to form micelles at certain concentration and temperature
Surfactant
-Hydrophilic polar head -Anionic, cationic, zwitterionic, non-ionic
-Non-polar long chain tail

Block co-polymers
-Hydrophilic polymer block (e.g PEG)
-Hydrophobic polymer block (e.g. PLA)

Micelles - Emulsions
CMC - critical micelle concentration
-Keep decreasing concentration of surfactant, it will hit certain point, and form a micelle

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