Ex 3. L7: Nanomedicine Flashcards
1
Q
Evolution of nanomedicine
A
COVID vaccine delivers nanolipid
-Small
-Cannot see with eyes
-Need electro microscope to visualize
2
Q
Nanoparticulate drug carriers
A
-Micelles/polymeric micelles
-Liposomes
-Protein nanoparticles
3
Q
Micelles
A
Surfactant molecules aggregate in aqueous solution to form micelles at certain concentration and temperature
Surfactant
-Hydrophilic polar head -Anionic, cationic, zwitterionic, non-ionic
-Non-polar long chain tail
Block co-polymers
-Hydrophilic polymer block (e.g PEG)
-Hydrophobic polymer block (e.g. PLA)
Micelles - Emulsions
CMC - critical micelle concentration
-Keep decreasing concentration of surfactant, it will hit certain point, and form a micelle