Evolution of Populations Flashcards
What is a common misconception about evolution?
That individual organisms evolve - natural selection acts on individuals, but only populations evolve
What would happen to a population of medium found finches during a drought?
The large-beak birds are more likely to crack large seeds and survive - the finch population evolves, not its individual members
What makes evolution possible?
Genetic variation
Variation in heritable traits is prerequisite for evolution by natural selection
Phenotype is the product of inherited genotype and environmental influences
Natural selection can only act on variation with a genetic component
What can genetic variation be measured as?
Gene variability or nucleotide variability
For gene variability, average heterozygosity measures the average percent of loci that are heterozygous in a population
What does the site of nucleotide variation dictate?
The site of nucleotide variation dictates the likelihood of phenotypic variation
Differences occur in non coding regions (introns) less likely to have an effect
Variations that occur in coding regions (exons) ‘can’ change the amino acid sequences of the coded protein
What are the major sources of genetic variation?
Sexual reproduction can result in genetic variation by recombining existing alleles
New genes and alleles can arise by mutation or gene duplication
What three random sources create fresh assortments of existing alleles every generation?
- crossing over
- independent orientation of homologous chromosomes at metaphase 1 of meiosis
- random fertilization
What serves as the raw material for evolution?
Mutations -creation of new alleles
- mutations are a “two-edged sword,” most being deleterious or neutral
- some mutations can be beneficial in instances when environment is changing such that mutations that were once disadvantageous are favorable under new conditions
What are the five main kinds of mutations?
- point mutations
- insertion / deletions (“indels”)
- gene duplication
- chromosome inversions
- polyploidization
Point mutation
Single-base substitutions caused by DNA polymerase errors in either:
- DNA synthesis
- DNA repair
Often referred to as Single Nucleotide Polymerase or SNPs
What does redundancy in genetic code allow for?
It allows for silent mutations to persist
Silent mutations
Have no effect at all on the genetic code
Missense mutation
Change the amino acid coding, produces a different amino acid
Leads to a base substitution that produces an improved protein that enhances the success of the mutant organism and its descendant
Nonsense mutation
Changing of an amino acid into a stop codon
What can deletion/insertion mutations result in?
- altering of the reading frame of the mRNA, so that nucleotides are grouped into different codons
- lead to significant changes in amino acid sequence downstrene of the mutation
- produce a nonfunctional polypeptide
A deletion
The loss of a chromosomal segment
A duplication
The repeat of a chromosome segment
An inversion
The reversal of a chromosome segment
A translocation
The attachment of a segment to a non homologous chromosome that can be reciprocal
Polyploidization
- polyploid organisms have more than 2 sets of chromosomes
- polyploidy usually occurs because of a failure in reduction division at meiosis which results in a 2n gamete