Evidence Based Flashcards

1
Q

what is SIMD and how is it derived

A

scottish index of multiple deprivation

based on income, housing, education, employment, access to services

1 most deprived
5 least deprived

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2
Q

how to know if a confidence interval is significant

A

if it does not contain 1

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3
Q

what does it mean if there is a large confidence range

A

small sample size
variability in data

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4
Q

reasons for increased oral cancer risk in those in lower socioeconomic groups

A

smoking
excessive alcohol
lack of education
limited access to healthcare
bad OH

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5
Q

what is PICO

A

population
intervention
comparison
outcome

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6
Q

study - effect of manual vs powered toothbrushes on plaque reduction
group - adults at GDP

give a PICO

A

population - adults attending GDP
intervention - powered toothbrush
comparison - manual toothbrush
outcome - reduction of plaque

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7
Q

explain randomised control trials

A

designed to evaluate the effectiveness of interventions or treatments

good for clinical trials, gold standard

randomised
control group
blinding
outcome measures
specification of participants [inclusion/exclusion criteria]

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8
Q

ways to minimise bias in a study

A

randomisation
- computer generated
- reduces selection bias, distributes unknown and confounding factors

blinding
- helps prevent conscious/unconscious bias, reduces detection bias, double blinding best

standardisation
- use same technique, time, etc

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9
Q

name the standards developed to improve the reporting of RCTs

A

CONSORT statement

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10
Q

explain cohort study

A

estimating incidence and cause of disease

prospective study

prospective study, establish group and measure exposures, follow over time

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11
Q

explain case control study

A

potential causes of disease

retrospective study

looks back to exposure of particular risk factrs

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12
Q

what are roles of epidemiology

A

measurement of amount/distribution of disease
study of causes/determinants of disease
assess risk of disease
development of preventative programmes

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13
Q

define incidence

A

number of new disease cases developing over a specific period of time in a defined population

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14
Q

define prevalence

A

number of disease cases in a population at a given time

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15
Q

what type of study would provide the highest level of evidence for the effectiveness of tx

A

meta analysis of systematic reviews and RCTs

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16
Q

absolute risk difference - what is it and how to calculate

A

difference in risk between groups

risk group 1 = x/x = A
risk group 2 = x/x = B

A - B = risk difference