Evidence Based Flashcards
what is SIMD and how is it derived
scottish index of multiple deprivation
based on income, housing, education, employment, access to services
1 most deprived
5 least deprived
how to know if a confidence interval is significant
if it does not contain 1
what does it mean if there is a large confidence range
small sample size
variability in data
reasons for increased oral cancer risk in those in lower socioeconomic groups
smoking
excessive alcohol
lack of education
limited access to healthcare
bad OH
what is PICO
population
intervention
comparison
outcome
study - effect of manual vs powered toothbrushes on plaque reduction
group - adults at GDP
give a PICO
population - adults attending GDP
intervention - powered toothbrush
comparison - manual toothbrush
outcome - reduction of plaque
explain randomised control trials
designed to evaluate the effectiveness of interventions or treatments
good for clinical trials, gold standard
randomised
control group
blinding
outcome measures
specification of participants [inclusion/exclusion criteria]
ways to minimise bias in a study
randomisation
- computer generated
- reduces selection bias, distributes unknown and confounding factors
blinding
- helps prevent conscious/unconscious bias, reduces detection bias, double blinding best
standardisation
- use same technique, time, etc
name the standards developed to improve the reporting of RCTs
CONSORT statement
explain cohort study
estimating incidence and cause of disease
prospective study
prospective study, establish group and measure exposures, follow over time
explain case control study
potential causes of disease
retrospective study
looks back to exposure of particular risk factrs
what are roles of epidemiology
measurement of amount/distribution of disease
study of causes/determinants of disease
assess risk of disease
development of preventative programmes
define incidence
number of new disease cases developing over a specific period of time in a defined population
define prevalence
number of disease cases in a population at a given time
what type of study would provide the highest level of evidence for the effectiveness of tx
meta analysis of systematic reviews and RCTs