Evasion of Innate Immunity Flashcards

1
Q

Which organism hijacks regulatory macrophages?

A

Leishmania overactivates

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2
Q

What part of immunity do listeria and TB evade?

A

Phagosome maturation

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3
Q

How is AIM2 avoided by Yersina?

A

Injects molecules into robust vacuoles not cytoplasm

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4
Q

How does KSHV evade inflammasome?

A

Encodes decoy that canny dimerise

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5
Q

How can bacteria/fungi/viruses/parasites evade complement?

A

Regulator mimics
Depletion of proteins
Antagonistic signalling

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6
Q

How can miRNA pathways be manipulated?

A

Bacteria use miRNA to induce latency

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7
Q

How does Anaplasma evade killing?

A

Hijacks vacuoles to evade ROS

Downregulates NADPH oxidase to reduce ROS

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