Evasion of Innate Immunity Flashcards
1
Q
Which organism hijacks regulatory macrophages?
A
Leishmania overactivates
2
Q
What part of immunity do listeria and TB evade?
A
Phagosome maturation
3
Q
How is AIM2 avoided by Yersina?
A
Injects molecules into robust vacuoles not cytoplasm
4
Q
How does KSHV evade inflammasome?
A
Encodes decoy that canny dimerise
5
Q
How can bacteria/fungi/viruses/parasites evade complement?
A
Regulator mimics
Depletion of proteins
Antagonistic signalling
6
Q
How can miRNA pathways be manipulated?
A
Bacteria use miRNA to induce latency
7
Q
How does Anaplasma evade killing?
A
Hijacks vacuoles to evade ROS
Downregulates NADPH oxidase to reduce ROS