Eukaryotic non-coding RNA Flashcards
1
Q
How much of the transcriptional output in eukaryotes is actually encoding a protein?
A
2%
2
Q
What is non coding RNA?
A
RNA that isn’t translated into a polypeptide
3
Q
How are non-coding RNAs transcribed and regulated?
A
Same way as mRNA is
4
Q
What are 4 classes of non-coding RNA? What are they categorized by?
A
Categorized by length. There are long, short, micro, and some functional classes
5
Q
What are two reasons why we’re interested in regulatory RNAs?
A
Play important roles in disease, and therapeutic targets for cancer treatment and other diseases
6
Q
When was the first miRNA discovered?
A
1993
7
Q
When was the first lncRNA discovered?
A
1996
