Eukaryotic gene transcription

Question 1

Result of a metabolic enzyme effecting transcription

Answer 1

Altered metabolism

Question 2

Results of a gene regulatory protein effecting transcription

Answer 2

Altered gene expression

Question 3

What is the result of a cytoskeletal protein effecting transcription

Answer 3

Altered cell shape or movement

Question 4

Remodelling of chromatin:

Answer 4

Results in increased promoter accessibility for transcription to initiate

Question 5

Where does an activator protein bind

Answer 5

The enhancer

Question 6

Where do regulatory proteins bind

Answer 6

The promoter (the promoter proximal elements region specifically)

Question 7

Activation domain of a transcriptional activator

Answer 7

Transcriptional activation (co-activators contains chromatin remodelling enzymes, co-activators/repressors, general transcription machinery)

Question 8

Regulatory domain

Answer 8

Responsible for dimerisation, nuclear transport, auto inhibition, cooperativity in DNA binding

Question 9

DNA binding domain

Answer 9

bring the transcription-activation domain into the vicinity of the promoter