etute3

Question 1

• Amoxicillin

Answer 1

• Extraction of penicillin from a fungal mould
• Broad activity against bacterial species
• Overcame limitations: sensitivity to stomach acid & resistance

Question 2

• Fexofenadine

Answer 2

• ancestor is diphenhydramine

- Overcame limitations: grogginess and sedation

Question 3

• Cefepime

Answer 3

• Extracted from acremonium mould

- Used to treat drug-resitant life-threatening infections

Question 4

• Celecoxib

Answer 4

• Overcame limitations: less damaging to gastrointestinal tract

Question 5

• Atorvastatin

Answer 5

• Used for atherosclerosis

- Overcame limitations: greater reduction in blood cholesterol

Question 6

• Atazanavir

Answer 6

• Block the enzymatic process of proteins that help with AIDS reproduction
• Overcame limitations: doesn’t disrupt lipid metabolism which causes buffalo humps