etute2

Question 1

• Synthetic drug

Answer 1

: human origin, made in a lab

Question 2

• Pathogen

Answer 2

an infectious agent that causes disease or illness

Question 3

• Pathogenesis

Answer 3

development of a disease and the chain of cellular events

Question 4

• Trained investigators

Answer 4

unbiased scientically-trained observers

Question 5

• Disease biomarkers

Answer 5

measurable indictor of a disease

Question 6

• Therapeutic class

Answer 6

drug family” where you would classify them into groups

Question 7

• Drug analogue

Answer 7

: similar but not identical chemical structure

Question 8

• Small molecule

Answer 8

drugs < 500g

Question 9

• Druggable target

Answer 9

– protein with a ligand binding site to which a drug can bind to alter the function

Question 10

• Ligand

Answer 10

– a molecule that binds to a druggable target

Question 11

• Docking

Answer 11

– the interaction of a drug molecule with its binding site

Question 12

• Candidate identification

Answer 12

tinkering with lead molecules to improve their ability to bind with targets