Ethical and Professional Practice of Science Flashcards

(98 cards)

1
Q

Define

Stanford prison experiment

A

a 1971 social psychology experiment, with questionable ethics, that attempted to investigate the psychological effects of perceived power, focusing on the struggle between prisoners and prison officers

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2
Q

Define

Informed consent

A

permission granted in full knowledge of the possible consequences, typically that which is given by a patient to a doctor for treatment with knowledge of the possible risks and benefits

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3
Q

Definition

guiding principles for more ethical use of animals in testing. They include: replacement, reduction and refinement

A

The 3Rs

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4
Q

Define

STAR technique

A

a structured manner of responding to a behavioral-based interview question by discussing the specific situation, task, action, and result of the situation you are describing

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5
Q

Definition

a type of bias that occurs in published academic research. It occurs when the outcome of an experiment or research study influences the decision whether to publish or otherwise distribute it

A

Publication bias

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6
Q

Definition

One of the 3Rs which specifies that, where possible, methods that minimise the number of animals used per experiment should be used in scientific research

A

Reduction

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7
Q

What are the two approaches to animal research?

A

Utilitarian view

Deontological view

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8
Q

Definition

animals that have a backbone or spinal column, also called vertebrae. These animals include fish, birds, mammals, amphibians, and reptiles

A

Vertebrate

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9
Q

Define

Andrew Wakefield

A

a discredited former British doctor who became an anti-vaccine activist. He was a gastroenterologist until he was struck off the UK medical register for unethical behaviour, misconduct and fraud

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10
Q

Define

Nuremberg code

A

a set of research ethics principles for human experimentation set as a result of the subsequent Nuremberg trials at the end of the Second World War

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11
Q

Who was the first person to clone a dog?

A

Woo Suk Hwang

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12
Q

Definition

a discredited former British doctor who became an anti-vaccine activist. He was a gastroenterologist until he was struck off the UK medical register for unethical behaviour, misconduct and fraud

A

Andrew Wakefield

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13
Q

Define

Declaration of Helsinki

A

a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and data

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14
Q

Define

Peer review

A

evaluation of scientific, academic, or professional work by others working in the same field

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15
Q

Define

Ethics

A

a set of moral principles, especially ones relating to or affirming a specified group, field, or form of conduct

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16
Q

What are the three ideals of science?

A
  1. Universalism
  2. Peer review
  3. Repetition
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17
Q

What type of animals do ethical procedures apply to?

A

Live, non-human vertebrates and most crustaceans

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18
Q

Define

Imperfect/stressful environment theory

A

a way of looking at human error that maintains that misconduct occurs because various institutional pressures, incentives, and constraints encourage people to commit misconduct

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19
Q

Definition

a structured manner of responding to a behavioral-based interview question by discussing the specific situation, task, action, and result of the situation you are describing

A

STAR technique

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20
Q

Definition

ethical theories that place special emphasis on the relationship between duty and the morality of human actions

A

Deontological approach

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21
Q

Definition

a set of research ethics principles for human experimentation set as a result of the subsequent Nuremberg trials at the end of the Second World War

A

Nuremberg code

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22
Q

Define

Replacement

A

One of the 3Rs which specifies that, where possible, animals should avoided or substituted for other methods in scientific research

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23
Q

Definition

results and ideas are judged by their own merit, not by the status or authority of the person presenting them

A

Universalism

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24
Q

Why was the Nuremberg code developed?

A

This was a direct response to the atrocities committed by some Nazis in the name of medical research

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25
# Definition a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and data
Declaration of Helsinki
26
# Definition a series of social psychology experiments with questionable ethics conducted by Stanley Milgram addressing aspects of obedience to authority figures
Milgram's experiment
27
# Definition an arthropod of the large, mainly aquatic group Crustacea, such as a crab, lobster, shrimp, or barnacle
Crustacean
28
At Monash, 'human research' refers to what?
Research conducted with or about people, or their data or tissue
29
True or False: You don't need ethical approval for simply observing the behaviour of an animal in their natural habitat
False
30
# Definition permission granted in full knowledge of the possible consequences, typically that which is given by a patient to a doctor for treatment with knowledge of the possible risks and benefits
Informed consent
31
What did Harry Harlow do?
Dr Harry Harlow separated mothers and babies at birth, initially to prevent infection. He found that the babies developed a lot of behavioural problems and did not parent their own babies well, leading to further experimentation to examine why these behavioural problems developed in separated infants. His work was an important part of realising, for example, that human premature babies need to be handled and have skin contact and not just be kept warm and given food
32
# Define Morals
standards of behaviour; principles of right and wrong
33
What were the results of Milgram's experiment?
Sixty percent of the "teachers" obeyed orders to punish the learner to the very end of the 450-volt scale! No subject stopped before reaching 300 volts!
34
# Define Employability
the attributes of a person that make that person able to gain and maintain employment
35
What are some examples of non-traditional jobs for scientists?
Law Public policy Actuarial work Blogger/podcaster Armed forces
36
# Definition The quality of being able to be exactly copied or reproduced
Replicability
37
What does the STAR technique include?
**S**ituation **T**ask **A**ction **R** esult
38
# Define Refinement
One of the 3Rs which specifies that, where possible, methods that minimise animal suffering and improve welfare should be used in experimental research
39
Which crustaceans are not covered under ethical guidelines?
Shrimps and *Daphnia*
40
# Definition One of the 3Rs which specifies that, where possible, methods that minimise animal suffering and improve welfare should be used in experimental research
Refinement
41
# Definition a 1971 social psychology experiment, with questionable ethics, that attempted to investigate the psychological effects of perceived power, focusing on the struggle between prisoners and prison officers
Stanford prison experiment
42
# Define Transferrable skills
Aptitude and knowledge acquired through personal experience such as schooling, jobs, classes, hobbies, sports etc.
43
# Define Utilitarian approach
an ethical theory that states that the best action is the one that maximizes utility. "Utility" is defined in various ways, usually in terms of the well-being of sentient entities
44
# Definition a way of looking at human error that maintains that misconduct occurs because various institutional pressures, incentives, and constraints encourage people to commit misconduct
Imperfect/stressful environment theory
45
# Define The Piltdown hoax
a paleoanthropological hoax in which bone fragments were presented as the fossilised remains of a previously unknown early human
46
# Define Fraud
wrongful or criminal deception intended to result in financial or personal gain.
47
# Define Universalism
results and ideas are judged by their own merit, not by the status or authority of the person presenting them
48
What was the skull from the Piltdown hoax actually made up of?
Part human, part orangutan
49
# Definition wrongful or criminal deception intended to result in financial or personal gain.
Fraud
50
What is the basis of the Helsinki code?
Nuremberg code
51
# Definition an ethical theory that states that the best action is the one that maximizes utility. "Utility" is defined in various ways, usually in terms of the well-being of sentient entities
Utilitarian approach
52
Which of the three ideals of science caught Hwang out?
Repetition - Stem cell researchers became sceptical about Hwang’s work when they could not repeat it
53
What did Milgram's experiment involve?
In Milgram’s experiment, so-called "teachers" (who were actually the unknowing subjects of the experiment) were recruited by Milgram. They were asked to administer an electric shock of increasing intensity to a "learner" for each mistake made during the experiment. The fictitious story given to these "teachers" was that the experiment was exploring effects of punishment (for incorrect responses) on learning behaviour. The "teacher" was not aware that the "learner" in the study was actually an actor - merely simulating discomfort as the "teacher" increased the electric shocks.
54
# Definition The famous experiments, with questionable ethics, that psychologist Harry Harlow conducted in the 1950s on maternal deprivation in rhesus monkeys
Harlow's experiment
55
# Define Woo Suk Hwang
a South Korean stem-cell researcher at the center of one of the largest investigations of scientific fraud due to the fabrication of results
56
What happened to Woo Suk Hwang after he was caught?
His papers were retracted
57
# Definition One of the 3Rs which specifies that, where possible, animals should avoided or substituted for other methods in scientific research
Replacement
58
# Definition A former geology professor at Yale University, who was arrested on charges of sexual assault and child porn possession
Tony Lasaga
59
# Definition a way of looking at human error that maintains that complex systems would be fine, were it not for the erratic behaviour of some unreliable people in it
Bad apple theory
60
# Definition five aspects of animal welfare under human control. They include: Freedoms from hunger or thirst; Freedom from discomfort; Freedom from pain, injury or disease; Freedom to express normal behaviour; Freedom from fear and distress
Five freedoms
61
# Definition a German physicist who briefly rose to prominence after a series of apparent breakthroughs with semiconductors that were later discovered to be fraudulent after using the same data in multiple papers
Jan Hendrik Schon
62
# Define Bad apple theory
a way of looking at human error that maintains that complex systems would be fine, were it not for the erratic behaviour of some unreliable people in it
63
# Define Jan Hendrik Schon
a German physicist who briefly rose to prominence after a series of apparent breakthroughs with semiconductors that were later discovered to be fraudulent after using the same data in multiple papers
64
What are the limits of peer review in detecting fraud?
Referees assume data have been honestly collected and focus more on logic and originality
65
# Define Crustacean
an arthropod of the large, mainly aquatic group Crustacea, such as a crab, lobster, shrimp, or barnacle
66
What is an example of a drug trial where participants were not adequately warned about side-effects?
Pfizer trial in Nigeria
67
# Definition Aptitude and knowledge acquired through personal experience such as schooling, jobs, classes, hobbies, sports etc.
Transferrable skills
68
# Define Publication bias
a type of bias that occurs in published academic research. It occurs when the outcome of an experiment or research study influences the decision whether to publish or otherwise distribute it
69
Why was Zimbardo's experiment aborted less than half way through?
psychological damage to prisoners, such as depression, and sadism on the part of guards
70
Why wouldn't universalism have caught Schön out?
most of us are impressed by reputation, and Schön was working with accomplished scientists in a famous laboratory
71
# Define Vertebrate
animals that have a backbone or spinal column, also called vertebrae. These animals include fish, birds, mammals, amphibians, and reptiles
72
# Define Tony Lasaga
A former geology professor at Yale University, who was arrested on charges of sexual assault and child porn possession
73
# Definition a paleoanthropological hoax in which bone fragments were presented as the fossilised remains of a previously unknown early human
The Piltdown hoax
74
Which of the three ideals of science meant that Schön was caught?
Peer review - similar graphs were detected in different papers. Further checks revealed more examples of duplications Repetition - People trying to repeat, or extend, Schön’s work must also have become sceptical
75
Which two researchers found that given the right set of circumstances, ordinary people will do things that are immoral or unethical, and even cruel?
Milgram and Zimbardo
76
What several factors can impact employability?
1. Ability to identify suitable job opportunities 2. Knowledge and abilities relating to a specific job 3. Self-presentation 4. External factors (i.e. job market, personal circumstances etc.)
77
Present day debates about the rights of animals go back a long way, but for our purposes we can start in the mid-1600s when Descartes claimed what?
He set out his arguments for animals being distinct from humans. Humans, he thought, were capable of complex functions including thought, whereas animals reacted automatically to stimuli and did not feel pain.
78
# Define Replicability
The quality of being able to be exactly copied or reproduced
79
What did Zimbardo's experiment involve?
Volunteers were assigned roles as ‘prisoners’ or ‘guards’. A part of the design involved humiliating prisoners in various ways (e.g. stripping and searching). The guards did whatever they judged necessary to keep the prisoners in order.
80
True or False: Informed consent does not always have to be written
False
81
What are some criticisms of Zimbardo's experiment?
Criticisms of the experiment include that there were no controls, that Zimbardo was not a neutral observer because he superintended the experiment, and that it does not enlighten us about behaviour because the volunteers were role-playing.
82
# Definition inclination or prejudice for or against one person or group, especially in a way considered to be unfair
Bias
83
# Define The 3Rs
guiding principles for more ethical use of animals in testing. They include: replacement, reduction and refinement
84
# Definition a South Korean stem-cell researcher at the center of one of the largest investigations of scientific fraud due to the fabrication of results
Woo Suk Hwang
85
What are the five freedoms?
1. From Hunger and Thirst: access to fresh water and good diet 2. From Discomfort: appropriate environment including shelter, resting area 3. From Pain, Injury or Disease: prevention / treatment 4. To Express Normal Behaviour: space, facilities, company of the animal's own kind 5. From Fear and Distress: conditions and treatment which avoid mental suffering
86
What was the first major turning point regarding human ethics?
Development of the Nuremberg code after WWII
87
# Define Deontological approach
ethical theories that place special emphasis on the relationship between duty and the morality of human actions
88
# Define Reduction
One of the 3Rs which specifies that, where possible, methods that minimise the number of animals used per experiment should be used in scientific research
89
# Define Harlow's experiment
The famous experiments, with questionable ethics, that psychologist Harry Harlow conducted in the 1950s on maternal deprivation in rhesus monkeys
90
Why are Milgram and Zimbardo's experiments considered unethical?
The controversy surrounding their experiments centres on the fact that the participants were not informed about the experiment (always a problem in psychology studies), the researchers scientific competence (they participated in the experiments, and in Zimbardo’s case were not controlled studies), and that researchers ran experiments in such a way that they harmed the participants.
91
What are the 3Rs?
Replacement Reduction Refinement
92
# Define Milgram's experiment
a series of social psychology experiments with questionable ethics conducted by Stanley Milgram addressing aspects of obedience to authority figures
93
# Definition standards of behaviour; principles of right and wrong
Morals
94
# Define Five freedoms
five aspects of animal welfare under human control. They include: Freedoms from hunger or thirst; Freedom from discomfort; Freedom from pain, injury or disease; Freedom to express normal behaviour; Freedom from fear and distress
95
# Definition evaluation of scientific, academic, or professional work by others working in the same field
Peer review
96
# Definition the attributes of a person that make that person able to gain and maintain employment
Employability
97
# Define Bias
inclination or prejudice for or against one person or group, especially in a way considered to be unfair
98
# Definition a set of moral principles, especially ones relating to or affirming a specified group, field, or form of conduct
Ethics