Ethanol Flashcards
1
Q
Elimination kinetics
A
Zero order, 0.015 BAC per hour
2
Q
Acute effects
A
Biphasic effects
Increased peripheral blood flow
Increased sociability, reduced anxiety
Spins from inner ear effects
Sedative effects
3
Q
Receptor targets
A
NMDA inhibition
Voltage gated Ca inhibition
GABA potentiation
4
Q
Tolerance mechanism
A
Upregulation of liver enzymes
Behavioral tolerance
Switch from glucose to acetate metabolism in brain
5
Q
Long term effects
A
Damage to stomach mucosa, leading to ulcers
Brain modification and damage
Decline in liver function
Increased cancer risk
