Essentials of Psychosis Flashcards

1
Q

Definition of neurosis

A

A relatively mild mental illness that is not caused by organic disease, involving symptoms of stress (depression, anxiety, obsessive behaviour, preoccupation with physical illnesses) but not a radical loss of touch with reality.

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2
Q

Define psychosis

A

Psychosis can be defined as grossly impaired reality testing .i.e. persons incorrectly evaluate the accuracy of their thoughts and perceptions and make incorrect inferences about external reality, even in the presence of contrary evidence.

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3
Q

Characteristics of psychosis

A

Psychosis is a broad term but is generally associated with severe impairment of social and personal functioning characterised by social withdrawal and inability to perform the usual social and household occupational roles
Lack of insight is a key feature

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4
Q

Empathy as a tool to understand a patient’s symptoms include:

A

this involves observation, questioning, re-phrasing and checking if you’ve got it right.

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5
Q

Explain the phrase “psychosis occurs on a continuum”

A

Occur on a continuum
One pole
Grossly disorganised speech and behaviour. Difficult or impossible to get a coherent account of the symptoms.
The other pole
Symptoms are mild and difficult to distinguish from “normal”
Can be very subtle and difficult to elicit
Between the poles fall the patients who’s symptoms are easier to spot.

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6
Q

List clinical features of psychosis

A

None of the symptoms alone is definitive of any disorder
Always entertain a differential diagnosis for each symptom, then settle on a diagnosis that fits the pattern best.

Delusions 
Hallucinations
Disorganised thinking (speech)
Grossly disorganised or abnormal motor behaviour (including catatonia)
Negative symptoms
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7
Q

List examples of psychotic disorders

A
Schizophreniform psychosis
Schizophrenia
Schizoaffective disorder
Bipolar disorder
Brief psychotic disorder
Psychosis secondary to another medical condition
Substance-induced psychosis
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8
Q

Define delusion

A

fixed, firmly held, false belief which is not amenable to change even in the face of contradictory evidence
The belief is out of keeping with that of the individual’s cultural group
And is not an article of faith or a religious belief

Distinction between a strongly held belief (overvalued idea) and a delusion is sometimes difficult to make and depends on the degree of conviction with which the belief is held despite clear or reasonable contradictory evidence regarding its veracity.

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9
Q

Name some of the themes of delusions

A
persecutory
religious
grandiose
somatic
referential
nihilistic
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10
Q

Explain non-bizarre delusions

A

Within realms of possibility but patently untrue

E.g. a belief that one is under surveillance by the police, despite a lack of any convincing evidence.

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11
Q

Explain bizarre delusions

A

If clearly implausible and not understandable to same culture peers and do not derive from ordinary life experiences
E.g. A belief that someone has implanted a chip in one’s brain and that this “other” is controlling one’s actions or behaviour.

Bizarre delusions include:

  • Thought withdrawal
  • Thought insertion
  • Delusions of control
  • Thought broadcasting
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12
Q

Delusions may be:

A

Systematized and fragmentary
Systematized forms an association of ideas that fit into a coherent narrative, even though implausible
Fragmentary are bits of poorly, or non- associated ideas

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13
Q

Name causes of delusions

A
Schizophrenia 
Bipolar Disorder
Delusional disorder
Schizoaffective disorder
Dementia 
Delirium 
Neoplasms 
Epilepsy
Traumatic brain injury
Vitamin deficiencies (pellagra)
Endocrinopathies (thyroid, etc.)
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14
Q

Define hallucinations

A

A sensory perception that has the compelling sense of reality of a true perception but that occurs without external stimulation of the relevant sensory organ.

Hallucinations should be distinguished from illusions, in which an actual external stimulus is misperceived or misinterpreted.

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15
Q

Describe features of hallucinations

A

Vivid and clear with full force and impact of normal perceptions
Not under voluntary control
May occur in any sensory modality
Auditory commonest
Sensorium must be clear
Hypnagogic (falling asleep) and hypnopompic (waking up) normal
May occur in religious context in certain cultures.

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16
Q

Types of hallucinations

A

Auditory - One or more voices, familiar or unfamiliar, Commentate, command, echo thoughts
Visual - Bizarre, transient, usually terrifying, not cinematic
Gustatory - Unexplained taste
Olfactory - Unexplained smell
Tactile - ‘crawling sensation’ on skin
Somatic - Sensations within the body – electric shocks, etc.

17
Q

Causes of hallucination

A

Auditory - Schizophrenia, bipolar mood disorder, schizoaffective dis., substance abuse/intoxication, dementia, tumours
Visual - Delirium (e.g. DT’s), stroke, neoplasm
Olfactory - Epilepsy (aura)
Gustatory - Epilepsy (aura)
Tactile - Alcohol withdrawal (DT’s)
Somatic - Substance abuse/intoxication, schizophrenia, BPAD

18
Q

Explain/define disorganized thinking

A
  • Formal thought disorder- a loss of the normal flow of thought; typically inferred from the individual’s speech.
  • Derailment/loosening of associations- jumping from topic to topic
  • Tangentiality-answer to a question may be obliquely related or completely unrelated
  • Incoherence/word salad – speech that is so severely disorganised as to be incomprehensible
19
Q

Thought disorders: What is meant by “flight of ideas”?

A

A nearly continuous flow of accelerated speech with abrupt changes from topic to topic that are usually based on understandable associations, distracting stimuli, or plays on words. When severe, speech may be disorganized and incoherent.

  • Characteristic of MANIA
20
Q

Thought disorder: What is meant by “loosening of associations”?

A
  • A disturbance of thinking shown by speech in which ideas shift from one subject to another that is unrelated or minimally related to the first.
  • Statements that lack a meaningful relationship may be juxtaposed, or speech may shift suddenly from one frame of reference to another. The speaker gives no indication of being aware of the disconnectedness, contradictions, or illogicality of speech.

Characteristic of SCHIZOPHRENIA

21
Q

Thought disorder: What is meant by “circumstantially”?

A

Pattern of speech that is indirect and delayed in reaching its goal because of excessive or irrelevant detail or parenthetical remarks. The speaker does not lose the point.

22
Q

What are the features of catatonia?

A

Decreased reactivity to the environment
Decreased mobility to complete unawareness or …
Purposeless and unstimulated excessive motor activity (‘catatonic excitement’)

Rigidity and maintenance of postures (‘waxy flexibility’)
Negativism: active resistance to instructions or attempts to move them
Posturing: assuming bizarre postures
Echolalia and echopraxia

23
Q

Causes of catatonia

A
Schizophrenia
Depression
Neurological disorders: 
- CVA, neoplasms, head trauma, encephalitis,
Metabolic: 
- hypercalcaemia, diabetic ketoacidosis, homocystinuria, hepatic encephalopathy
Dementia
Delirium
24
Q

Features of disorganized behaviour

A

Poor self care
Unkempt appearance
Poor self hygiene and inability to perform activities of daily living (e.g. shopping, cooking etc)
Inappropriate and bizarre behaviour
- E.g. public masturbation, exhibitionism, unusual dress (layers
of mismatching clothing)
Child-like silliness to gross agitation

25
Q

Causes of disorganized behaviour

A

This is the most non-specific sign of psychosis.

Can be caused by any serious psychiatric or neuropsychiatric disorder

But its presence indicates severity of illness

26
Q

Explain features of schizophrenia: aetiology, tests, onset, progression of disease

A

Affects approximately 1 per 100 people across all cultures

Aetiology unknown. Likely a cluster of disorders

No specific diagnostic tests available; therefore, diagnosis made clinically based on characteristic symptoms and signs and after excluding primary organic disorders.

Onset in males tends to be younger than in females; usually late teens/early twenties; often has a poorer prognosis

Tends to run a relapsing and remitting course with gradual, progressive deterioration. However, 10-20% will have a single episode and are symptom free thereafter, although more vulnerable (e.g. unemployment, relationship conflicts, poverty, psychoactive drugs may serve as potential triggers)

27
Q

Schizophrenia symptoms

A

Symptoms divided into positive (hallucinations, delusions, disorders of thought form) and negative symptoms (loss of volition, motivation, spontaneous behaviour, social withdrawal, anhedonia, affective flattening and poverty of thought and speech, termed alogia)

28
Q

Commonest cause of premature death

A

Suicide - particularly in the first year post diagnosis. Approx. 10%

29
Q

Management of schizophrenia

A

Management plan based on biological (first and second generation antipsychotics) and non-biological (family interventions, education, supportive counselling, attending to basic needs such as accommodation) treatment approaches.

Evidence that early intervention during prodrome or first episode improves long-term prognosis. (EISH program at Valkenberg Hospital)

30
Q

Explain type 1 and type 2 diabetes

A

Bipolar disorder type 1- episodes of mania and (possibly less severe) depression. May also include “mixed episodes”, with features of mania and depression simultaneously

Bipolar disorder type 2- episodes of hypomania and (possibly more severe) depression.

If psychotic features while mood elevated=mania (type 1, even if not that energetic/disruptive)
Psychosis can occur with depressive episodes and indicate severity.