Essential Tremor Flashcards
motor system involved in mostly voluntary muscle movement
pyramidal
motor system that target neurons in spinal cord responsible for control of motor tone, movement amount/velocity, suppression of undesirable motor activity, and reflexes
extrapyramidal
motor system that is direct and monosynaptic
pyramidal
motor system that is indirect and polysynaptic
extrapyramidal
which component of the extrapyramidal system is responsible for excitatory output?
cerebellum
which component of the extrapyramidal system is responsible for inhibitory output?
basal nuclei
that most common cause of action (postural) tremor
essential tremor
where is the problem in essential tremor most likely localized? (2)
brainstem
cerebellum
what 2 actions can initiate an essential tremor?
voluntary movement
fixed posture against gravity
how does essential tremor affect one side of the body vs the other? (2)
bilateral
asymmetric
what part of the body is NOT involved in essential tremor?
legs
what 3 difficulties will a patient report having?
difficulty handwriting
manual skill difficulty
difficullty speaking
what makes an essential tremor worse?
anxiety/excitement
what makes an essential tremor improve?
mild alcohol consumption
what 4 criteria must be met to be diagnosed with essential tremor?
bilateral upper limb action tremor
for at least 3 years
can involve tremor in other locations
absence of other neurological signs
what should all patients with essential tremor receive?
referral to neurologist
what’s important to remember about treatment for essential tremor?
not needed if symptoms are mild
what 3 medication options can be used for mild, situational exacerbations of essential tremor?
propranolol
alprazolam
primidone
what medication can be used for persistent functional or psychological disability? (2)
propranolol
primidone
OR BOTH
what are 2 medication options if a patient has continuous symptoms despite treatment?
topiramate
gabapentin
what can be used for essential tremor in the head or voal cord if all medications fail?
botulinum toxin A
what can be used for essential tremor of the limbs if all medications fail? (2)
deep brain stimulation/thalamotomy