Esophageal Cancer

Question 1

Adenocarcinoma is found in

Answer 1

distal third of the esophagus

Question 2

Adenocarcinoma is associated with

Answer 2

long-standing GERD and Barrett esophagus

Question 3

Esophageal cancer is linked to the synergistic, carcinogenic effect of

Answer 3

alcohol and tobacco use

Question 4

squamous cell cancer is found in

Answer 4

proximal two-thirds of the esophagus.

Question 5

What is the Clinical Presentation of esophageal cancer?

Answer 5

1-progressive dysphagia first for solid
food, then for liquids
2-Weight loss
3-Rarely, halitosis, regurgitation, and hoarseness
4-Hypercalcemia

Question 6

How to diagnose esophageal Cancer?

Answer 6

1-barium swallow first
2-endoscopy is mandatory because this diagnosis requires a tissue biopsy.
3-CT scan detects the degree of local spread
4-bronchoscopy detects asymptomatic spread into the bronchi
5-Endoscopic U/S is performed for staging

Question 7

What is the treatment of esophegeal cancer?

Answer 7

1-surgical resection if localized to esophagus.

2-Chemotherapy with a 5-fluorouracil combined with radiation to control locally metastatic disease.