ESAP 2013 Flashcards
Is the tumor usually apparent if a patient has tumor-induced hypoglycemia?
Yes
Since most plasma ACTH assays cannot reliably detect subnormal or suppressed levels, experts suggest proceeding with adrenal imaging in patients with endogenous hypercortisolism who have ACTH concentrations less than ____ pg/mL.
25
Nutritional support is required when a patient has had poor nutrition for ____ days.
7
What effect does rifampin have on thyroid hormones?
Accelerates metabolism of T3 and T4 by augmenting deiodinases.
Does rifampin increase TSH?
Only in patients who already have hypothyroidism and are treated by levothyroxine.
Patient has:
- Marked hypercalcemia
- Renal insufficiency
- Alkalosis
Diagnosis?
Milk-alkali syndrome
Can fenofibrate and simvastatin be used together?
Yes
How is fetal hyperthyroidism treated?
By administering methimazole to the mother
What does an ankle-brachial index of more than 1.3 suggest?
Non-compressible vessels
What are the two methods of measuring macroprolactin?
- Gel filteration
- Polyethylene glycol precipitation
If patients are treated for Cushing’s disease with mifepristone then when does it need to be discontinued?
If adrenal insufficiency develops.
Can alendronate be used in renal transplant patients?
Yes
Which is better for localizing an insulin secreting tumor endoscopic ultrasonography or PET with F-DOPA in adults?
Endoscopic ultrasonography
Is hospitalization usually required for superficial diabetic foot ulcers?
No
What is the dose of alendronate for Paget’s disease?
40 mg daily for 3 - 6 months
What vaccination is indicated immediately after the diagnosis of diabetes?
Hepatitis B series
Patient has:
- Bilateral pheochromocytomas
- Signs of cerebellar dysfunction
- Renal cell carcinoma
Diagnosis?
VHL (von Hippel-Lindau) syndrome
If the total testosterone is discordant with the clinical picture then what’s the next step?
Free testosterone measurement
What happens to the fluid status of a patient after a pheochromocytoma is resected?
They are volume depleted.
What do you need to make sure the patient doesn’t have when you see an elevated 1,25 (OH) vitamin D level?
Sarcoidosis
What should you do to screen families who have a patient in the family with medullary thyroid carcinoma?
Molecular genetic testing for a RET proto-oncogene mutation
Does androgenic alopecia require further management?
No
How do you diagnosis osteonecrosis?
MRI
Does hypothyroidism increase cholesterol or triglycerides?
Both
Metformin treatment can decrease testosterone levels in patients with PCOS.
True or false?
True
How is calciphylaxis diagnosed?
By skin biopsy
Which therapy provides men with gonadal protection in the setting of chemotherapy?
Testosterone
Which gene mutation causes polyhormonal pituitary failure?
PROP 1
What disease causes urticaria pigmentosa?
Systemic mastocytosis
How is systemic mastocytosis confirmed if there are no skin findings?
Bone biopsy
What is the difference between a prolactin-producing pituitary carcinoma and an aggressive prolactinoma?
A pituitary carcinoma has at least one other metastasis (usually intra-cranial)
What is the treatment for bullosis diabeticorum (diabetic bullae)?
Reassurance
Mutation in SCNN1B or SCNN1G causes…
Liddle syndrome
Should you take out an adrenal mass in a patient with MEN2A even though the metanephrines are normal?
Yes
What pregnancy category is gemfibrozil?
Pregnancy category C
“Frozen shoulder” is a common complication of type 1 and type 2 diabetes.
True or false?
True
Which malignancies (2) are associated with osteoblastic bone metastasis?
- Prostate cancer
- Breast cancer
Can hypocalcemia cause reversible congestive heart failure?
Yes - rarely
When would you want to be careful before giving radioactive iodine in Graves’ disease?
When they have Graves’ ophthalmopathy
Patient has:
- Amenorrhea (primary)
- Lack of secondary sexual characteristics
- Hypertension and hypokalemia
- Suppressed aldosterone and renin
Diagnosis?
17 alpha-hydroxylase (CYP17) deficiency
