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ABIM - Endocrinology > ESAP 2013 > Flashcards

ESAP 2013 Flashcards

1
Q

Is the tumor usually apparent if a patient has tumor-induced hypoglycemia?

A

Yes

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2
Q

Since most plasma ACTH assays cannot reliably detect subnormal or suppressed levels, experts suggest proceeding with adrenal imaging in patients with endogenous hypercortisolism who have ACTH concentrations less than ____ pg/mL.

A

25

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3
Q

Nutritional support is required when a patient has had poor nutrition for ____ days.

A

7

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4
Q

What effect does rifampin have on thyroid hormones?

A

Accelerates metabolism of T3 and T4 by augmenting deiodinases.

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5
Q

Does rifampin increase TSH?

A

Only in patients who already have hypothyroidism and are treated by levothyroxine.

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6
Q

Patient has:

  • Marked hypercalcemia
  • Renal insufficiency
  • Alkalosis

Diagnosis?

A

Milk-alkali syndrome

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7
Q

Can fenofibrate and simvastatin be used together?

A

Yes

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8
Q

How is fetal hyperthyroidism treated?

A

By administering methimazole to the mother

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9
Q

What does an ankle-brachial index of more than 1.3 suggest?

A

Non-compressible vessels

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10
Q

What are the two methods of measuring macroprolactin?

A
  • Gel filteration

- Polyethylene glycol precipitation

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11
Q

If patients are treated for Cushing’s disease with mifepristone then when does it need to be discontinued?

A

If adrenal insufficiency develops.

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12
Q

Can alendronate be used in renal transplant patients?

A

Yes

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13
Q

Which is better for localizing an insulin secreting tumor endoscopic ultrasonography or PET with F-DOPA in adults?

A

Endoscopic ultrasonography

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14
Q

Is hospitalization usually required for superficial diabetic foot ulcers?

A

No

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15
Q

What is the dose of alendronate for Paget’s disease?

A

40 mg daily for 3 - 6 months

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16
Q

What vaccination is indicated immediately after the diagnosis of diabetes?

A

Hepatitis B series

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17
Q

Patient has:

  • Bilateral pheochromocytomas
  • Signs of cerebellar dysfunction
  • Renal cell carcinoma

Diagnosis?

A

VHL (von Hippel-Lindau) syndrome

18
Q

If the total testosterone is discordant with the clinical picture then what’s the next step?

A

Free testosterone measurement

19
Q

What happens to the fluid status of a patient after a pheochromocytoma is resected?

A

They are volume depleted.

20
Q

What do you need to make sure the patient doesn’t have when you see an elevated 1,25 (OH) vitamin D level?

A

Sarcoidosis

21
Q

What should you do to screen families who have a patient in the family with medullary thyroid carcinoma?

A

Molecular genetic testing for a RET proto-oncogene mutation

22
Q

Does androgenic alopecia require further management?

A

No

23
Q

How do you diagnosis osteonecrosis?

A

MRI

24
Q

Does hypothyroidism increase cholesterol or triglycerides?

A

Both

25
Q

Metformin treatment can decrease testosterone levels in patients with PCOS.

True or false?

A

True

26
Q

How is calciphylaxis diagnosed?

A

By skin biopsy

27
Q

Which therapy provides men with gonadal protection in the setting of chemotherapy?

A

Testosterone

28
Q

Which gene mutation causes polyhormonal pituitary failure?

A

PROP 1

29
Q

What disease causes urticaria pigmentosa?

A

Systemic mastocytosis

30
Q

How is systemic mastocytosis confirmed if there are no skin findings?

A

Bone biopsy

31
Q

What is the difference between a prolactin-producing pituitary carcinoma and an aggressive prolactinoma?

A

A pituitary carcinoma has at least one other metastasis (usually intra-cranial)

32
Q

What is the treatment for bullosis diabeticorum (diabetic bullae)?

A

Reassurance

33
Q

Mutation in SCNN1B or SCNN1G causes…

A

Liddle syndrome

34
Q

Should you take out an adrenal mass in a patient with MEN2A even though the metanephrines are normal?

A

Yes

35
Q

What pregnancy category is gemfibrozil?

A

Pregnancy category C

36
Q

“Frozen shoulder” is a common complication of type 1 and type 2 diabetes.

True or false?

A

True

37
Q

Which malignancies (2) are associated with osteoblastic bone metastasis?

A
  • Prostate cancer

- Breast cancer

38
Q

Can hypocalcemia cause reversible congestive heart failure?

A

Yes - rarely

39
Q

When would you want to be careful before giving radioactive iodine in Graves’ disease?

A

When they have Graves’ ophthalmopathy

40
Q

Patient has:

  • Amenorrhea (primary)
  • Lack of secondary sexual characteristics
  • Hypertension and hypokalemia
  • Suppressed aldosterone and renin

Diagnosis?

A

17 alpha-hydroxylase (CYP17) deficiency

ABIM - Endocrinology (17 decks)

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