Erythroid Flashcards
what are these cells?
what are aggregates and punctates, what is the differnece between the two?
these are reticulocytes (they still contain RNA)
The RNA is seen as small dots - punctate and larger clumps - aggregate
Aggregate have more RNA because they are younger
what is seen here in this reticulocyte?
polychromatophil
what are these?
ghost cell - cells that have ruptured in circulation and lost their haemoglobin
* in vitro haemolysis (artifact)
* in vivo intravascular haemolysis - will also have haemoglobinaemia and haemoglobinuria
describe the RBC shape seen here? why does this happen?
Poikilocytosis
* abnormal erythropoeisis
* diseases associated with erythrocyte fragmentation or oxidative damage
what word would you describe these cells?
Codocytes (target cells)
what word would you describe these cells?
Acanthocytes (spur cells)
From Greek acantha meaning “thorn”
what word would you describe these cells?
Echinocytes (burr cells)
From Greek ἐχῖνος (ekhînos, “hedgehog; sea urchin”)
what word would you describe these cells?
Schistocyte (or schizocyte)
From Greek σχίζω (skhízō, “I split”)
what are these cells?
Spherocytes
small, dark, spherical RBCs, lack central pallor
not typically recognized in cats, horses and cattle since normal RBCs have less of central pallor than in dogs
what abnormal structure can you see in these RBCs?
heinz bodies
what are the two cell types seen her?
- multiple, small, dark blue, punctate aggregates in RBC
- aggregates of ribosomes
what cells are seen here?
nucleated RBCs and RBCs
what is seen here?
Infectious agent -
Babesia within RBCs
what is seen here?
Howell-jolly bodies - single dark blueish bodies in RBCs of variable size
representing nuclear remnants
what is seen here?
Infectious agent - bacteria within RBCs
