Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Roomies Collab Deck 3: Surgery, Anesthesiology, Pain, and Urology > Erectile dysfunction > Flashcards

Erectile dysfunction Flashcards

1
Q

What are the risk factors for erectile dysfunction? (5)

A 
Sedentary lifestyle
Obesity
Smoking
Hypercholesterolaemia
Metabolic syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Erectile dysfunction increases the risk of (?) disease.

A

cardiovascular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

All men with unexplained erectile dysfunction should be evaluated for the presence of (?) and any identified risk should be addressed.

A

cardiovascular risk factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the first-line drug treatment for erectile dysfunction?

A

Oral phosphodiesterase type-5 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

In the treatment of erectile dysfunction, oral phosphodiesterase type-5 inhibitors act by …

A

increasing the blood flow to the penis

They do not initiate an erection—sexual stimulation is required.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name 3 short-acting oral phosphodiesterase type-5 inhibitors

A

Avanafil
Sildenafil
Vardenafil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Avanafil, sildenafil and vardenafil are (?)-acting phosphodiesterase type-5 inhibitors

A

short

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name one longer-acting oral phosphodiesterase type-5 inhibitor

A

Tadalafil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tadalafil is a (?)-acting phosphodiesterase type-5 inhibitor

A

longer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

If a patient with erectile dysfunction would like to have spontaneous (rather than scheduled) sexual activity or has frequent sexual activity, which oral phosphodiesterase type-5 inhibitor would be preferred?

A

Tadalafil

Longer-acting drug that can be used as a regular lower daily dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A patient with erectile dysfunction should receive (?) doses of an individual phosphodiesterase type-5 inhibitor at the maximum dose (with sexual stimulation) before being classified as a non-responder.

A

six

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A patient with erectile dysfunction should receive six doses of an individual phosphodiesterase type-5 inhibitor at the maximum dose (with (?)) before being classified as a non-responder.

A

sexual stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A patient with erectile dysfunction should receive six doses of an individual phosphodiesterase type-5 inhibitor at the maximum dose (with sexual stimulation) before being classified as a (?).

A

non-responder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is a second-line therapy for erectile dysfunction?

A

Alprostadil (prostaglandin E1) by intracavernosal, intraurethral or topical application

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Patients should be advised to seek medical help if a prolonged erection lasting (?) occur

A

4 or more hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

If a patient has a prolonged erection, what can they do at home that may help by opening the venous valves?

A

Apply an ice pack to the upper-inner thigh (alternating between left and right thighs every two minutes for up to 10 minutes)

17
Q

If priapism has lasted more than 6 hours, treatment should not be delayed. What is the initial therapy?

A

Penile aspiration

Using aseptic technique, 20–50mL of blood should be aspirated using a 19–21 gauge butterfly needle inserted into the corpus cavernosum; if necessary the procedure may be repeated on the opposite side

18
Q

Adrenaline/epinephrine:

Acts on both (?) and (?) receptors and increases both heart rate and contractility (beta1 effects); it can cause peripheral vasodilation (a beta2 effect) or vasoconstriction (an alpha effect).

A

alpha

beta

19
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both (?) and (?) (beta1 effects); it can cause peripheral vasodilation (a beta2 effect) or vasoconstriction (an alpha effect).

A

heart rate

contractility

20
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both heart rate and contractility ((?) effects); it can cause peripheral vasodilation (a beta2 effect) or vasoconstriction (an alpha effect).

A

beta-1

21
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both heart rate and contractility (beta1 effects); it can cause (?) (a beta2 effect) or vasoconstriction (an alpha effect).

A

peripheral vasodilation

22
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both heart rate and contractility (beta1 effects); it can cause peripheral vasodilation (a (?) effect) or vasoconstriction (an alpha effect).

A

beta-2

23
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both heart rate and contractility (beta1 effects); it can cause peripheral vasodilation (a beta2 effect) or (?) (an alpha effect).

A

vasoconstriction

24
Q

Adrenaline/epinephrine:

Acts on both alpha and beta receptors and increases both heart rate and contractility (beta1 effects); it can cause peripheral vasodilation (a beta2 effect) or vasoconstriction (an (?) effect).

A

alpha

25
Q

What is the indication for the use of alprostadil?

A

Erectile dysfunction

26
Q

Name 3 conditions that have a predisposition to priapism

A

Sickle cell disease
Multiple myeloma
Leukaemia

CAUTION when prescribing phosphodiesterase type-5 inhibitors

27
Q

When may phosphodiesterase type-5 inhibitor prescriptions be potentially potentially inappropriate in the elderly (STOPP criteria)? (2)

A

Severe heart failure characterised by hypotension (systolic BP < 90)
Concurrent nitrate therapy for angina (risk of cardiovascular collapse)

28
Q

What are the two indications for the use of metaraminol?

A

Acute hypotension

Priapism

29
Q

What three drugs given via intracavernosal injection can be used if penile aspiration and lavage are unsuccessful in treating priapism?

A

Phenylephine hydrochloride
Adrenaline/epinephrine
Metaraminol

All are unlicensed for this indication

30
Q

What are the three indications for the use of phenylephrine hydrochloride?

A

Mydriasis
Acute hypotension
Priapism

31
Q

What are the three indications for the use of sildenafil?

A 
Pulmonary arterial hypertension 
Erectile dysfunction 
Digital ulcers (associated with systemic sclerosis)
32
Q

What are the contraindications for the use of sildenafil? (8)

A
  1. Hereditary degenerative retinal disorders
  2. History of non-arteritic anterior ischaemic optic neuropathy
  3. Recent MI
  4. Recent stroke

When used for erectile dysfunction

  1. Systolic BP < 90
  2. If vasodilation or sexual activity are inadvisable
  3. Recent unstable angina

When used for pulmonary arterial hypertension
8. Sickle cell anaemia

33
Q

What are the common side effects of sildenafil? (20)

A 
Alopecia
Anaemia
Anxiety
Cough
Diarrhoea
Dizziness
Fluid retention
GI discomfort
GI disorders
Headaches
Increased risk of infection 
Insomnia
Nasal complaints
Nausea
Night sweats 
Pain 
Skin reactions
Tremor
Vasodilation 
Vision disorders
34
Q

The onset of phosphodiesterase type-5 inhibitors when used for erectile dysfunction may be delayed if taken with (?)

A

food

35
Q

What are the three indications for the use of tadalafil?

A

Pulmonary arterial hypertension
Erectile dysfunction
Benign prostatic hyperplasia

36
Q

What is the indication for the use of vardenafil?

A

Erectile dysfunction

Roomies Collab Deck 3: Surgery, Anesthesiology, Pain, and Urology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions