ER Exam 1 Flashcards
What is a nabothian cyst and its significance in a colposcopy?
mucus-filled cyst on the surface of the cervix occurs when columnar epithelium is engulfed and covered by squamous
can look abnormal because always covered with vasculature - can be mistaken for abnormal vessels but it doesn’t suggest CA
When do you do a cervical exisional procedure?
If an endocervical curretage/bx is positive
or
unsatisfactory colposcopy performed (can’t see SCJ)
or
substantial difference btw pap and biopsy
When is the estimated date of confinement (delivery)?
40 weeks after first day of last menstrual period (FDLMP)
Why do up to 40% of women have some vaginal bleeding during early pregnancy?
implantation bleeding
What level of hCG is reached about the time of expected menstruation?
What level of hCG is considered negative?
What level can a pregnancy test detect?
menses = 100
negative < 5
preg test = 25
What is the definition of a biochemical pregnancy?
presence of hCG 7-10 d after ovulation in a woman w/ regular cycles
When is the risk of fetal loss decreased to 2%?
if US reveals a live appropriately grow fetus at 8 weeks w/ + cardiac activity
What is an abortus?
fetus lost before 20 weeks
less than 500 g
How many threatened abortions eventually result in loss of pregnancy?
25-50%
Is the cervix closed or open in a complete abortion?
closed
What is the tx for a septic abortion?
ampicillin
gentamycin
clindamycin
How large is a blighted ovum?
> 25 mm
What is asherman syndrome?
rare acquired syndrome where scarring and adhesions form in the uterus due to trauma
often due to aggressive abortions –> destroys basalis layer
when does cervical incompetence typically cuase loss of pregnancy?
second trimester
What is the leading cause of maternal death in the first trimester?
ectopic pregnancy
(trophoblasts implant into mucosa of fallopian tube and rapidly erode through to the underlying blood vessels)
What is the difference in ectopic locations in natural conception vs assisted conception?
in natural, >95% are tubal
after ART, 92.7% are ampullary
What is the arias-Stella reaction?
thickened endometrial stripe seen in an ectopic pregnancy
When do you check hCG after giving a methotrexate dose for ectopic pregnancy?
day 4 and 7
will initially increase on day 4
if no decrease on day 7, give another dose
What are relative contraindications of methotrexate use for ectopic pregnancy?
gestational sac 3.5 cm or greater
embryonic cardiac motion
hCG levels > 6000
When do most ectopics resolve spontaneously?
80% will with hCG levels < 1000
What is a salpingostomy?
cut into tube to remove ectopic –> don’t sew it up, let it heal by secondary intention
(vs salpingotomy = sew it up)
What ethnic group has the most RhD negative people?
15%
How much fetal blood is needed to cause isoimmunization?
When does this blood transfer typically occur?
0.1 ml or less
usually during routine vaginal deliveries
1-2% occur in antipartum period
When do you administer rhoGam?
28 weeks
within 72 hrs after delivery of Rh D positive infant
When is the risk of intrauterine transfusion for an anemic baby greater than the risk of delivery?
at 35 weeks –> consider delivery and transfusing the neonate
What are normal cardiac sounds heard during pregnancy?
systolic murmurs
exaggerated splitting and S3
What is chadwick’s sign?
bluish discoloration of cirvix, vagina, and labia from increased blood flow
normal during pregnancy
What infections are screened for at a first prenatal visit?
rubella (vaccinate postpartum if not immune)
syphilis
Hep B surface Ag
HIV
gonorrhea and chlamydia
DM
Urine culture
When is a fetal pole seen?
6 weeks
when mean hCG is 5200
What measurements determine due date btw 6-11 weeks?
What about 12-20 weeks?
6-11 weeks –> crown rump length can det due date w/in 7 days
12-20 weeks –> femur length, biparietal diameter, and abdominal circumference can est w/in 10 days
How is fetal demise diagnosed in first trimester (based on CRL)?
if CRL > 5 mm w/ absence of fetal cardiac activity
What is the incidence for trisomy in women under 35, 35-39, 40-45, and >45?
< 35 –> 1 in 800
35-39 –> 1 in 300
40-45 –> 1 in 80
>45 –> 1 in 35
What are aminopterin and methotrexate?
both folic acid antagonists (chemo drugs)
exposure before 40 days is lethal
later exposure causes other se
How does valproid acid affect a fetus?
(anticonvulsant med)
1-2% risk of open spina bifida
some assoc w/ heart, skeletal, and craniofacial defects
What is carbamazepine and its assoc w/ pregnancy?
anticonvulsant
increased risk for spina bifida and other minor defects
What defects can retinoids cause?
CNS
cardiovascular
craniofacial (microcephaly w/ severe ear abn, microtia and cleft palate)