er and golgi Flashcards
1
Q
brief overview of the secretory pathway
A
nucleus > RER > transport vesicle > cis Golgi > sorting > trans Golgi > secretory granule/transport vesicle
2
Q
structure of the ER
A
continuous network of membrane tubules, continuous with nuclear envelope
3
Q
functions of ER
A
protein synthesis, glycosylation, folding, assembly of multi protein complexes, lipid synthesis - cholesterol, phospholipids, Ca2+ sequestration, detoxification by cytochrome P450 enzymes
4
Q
overview of the central dogma
A
DNA transcribed into mRNA, mRNA processed, then translated into protein