Equipment Flashcards
Rodent cervical dislocator
Large & Small Animal Decapitator (Guillotine)
Microwave Fixation System: Used to euthanize rodents < 500 g; provides immediate deactivation & fixation of brain enzymes & chemicals (acetylcholine, dopamine, DOPAC, HVA, and c-AMP).
Grip Strength Meter:
measures force required to make a mouse or rat release its grip. Effects of drugs, muscle relaxants, disease, or aging or neural damage on muscle strength may be assessed.
Hole Board Test:
Measures drug effects on exploratory behavior in mice. Infrared detector in each hole records mouse probing behavior.
Activity Chambers
Eight Arm Radial Arm Maze:
Rodents in search of food use visual environmental signals and complex spatial strategies and do not return to previously-visited locations, known as the win-shift strategy. The solution to the Olton Octagonal Maze (OOM) involves Working Memory (WM).
Morris Water Maze (just add water):
MWM task involves placing the rodent in a pool of water where it must use visual cues to remember the location of a hidden platform just below the water’s surface. Probe trial (transfer tests) are also used to assess the rodent’s ability to retrieve information learned in previous hidden platform tests.
Skinner box
Skinner box
B.F. Sknner’s elaboration of the theory od reinforcement and his advocacy of its application helped to establish the Behaviorism and Programmed Insruction movement.
Malaguard Sound Attenuating Cubicle with Viewing Port (Operant Test Chamber)
Shuttle avoidance box:
Discriminated avoidance learning, shuttle box behaviors, crossing’s behavior
Shuttle avoidance box (top view)
Hot Plate Analgesia Test
Measures latency of sterotyped paw lick response after dropping mouse or rat onto how surface (30-60 C)
Plantar Analgesia Test
Measures paw sensitivity to heat stimulation similar to Hot Plate Test, however, animal is unrestrained and heat is applied to bottom of single foot after animal is at rest. Repeated testing does not result in sensitization.
Rat stereotaxic apparatus
Dog/Monkey adapter for sterotaxic apparatus:
blunt ear bars
Fluid percussion device
Used to induce brain injury in rats with cephalic caps
Fluid percussion device
Used to induce brain injury in rats with cephalic caps
Rodent treadmill
Rotarod treadmill
Used to assess effects of drugs, brain damage, or diseases on motor coordination or fatigue resistance. Mouse and rat models; constant or accelerating speed models; drum has non-slip surface.
Tail Flick Analgesia Test
Test for analgesic effects. Rodent’s tail is placed over window on platform while being restrained. Intense beam of light is applied to tail (60-170 C) and latency period is measured until tail is flicked out of the light beam.
Infant ventilator
Havard Apparatus Respiratory Pump
